Zobrazeno 1 - 10
of 10
pro vyhledávání: '"I Iu Nagaev"'
Publikováno v:
Bioorganicheskaia khimiia. 39(3)
Proteolysis of Pro-Gly-Pro-Leu, Pro-Gly-Pro-Gly and Pro-Gly-Pro were studied comparatively to Met-Glu-His-Phe-Pro-Gly-Pro (semax). It is shown that all three peptides are considerably more stable to proteolysis by N-leucine-aminopeptidase (EC 3.4.11.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff745aad672af1adf5c9a20c87486fd7
https://pubmed.ncbi.nlm.nih.gov/24397030
https://pubmed.ncbi.nlm.nih.gov/24397030
Publikováno v:
Russian Journal of Bioorganic Chemistry. 28:231-233
6-O-(3-Methoxycarbonylpropyl)- and 6-O-(3-carboxypropyl)oximes of 16 alpha,17 alpha-cyclohexanopregn-4-ene-3,6,20-trione labeled by tritium in position 1,2 were synthesized. When using homogenous catalysts, the molar radioactivity of the resulting pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f822661c42d116b686fd379d3151d14a
https://doi.org/10.1023/a:1015712505616
https://doi.org/10.1023/a:1015712505616
Publikováno v:
Bioorganicheskaia khimiia. 37(4)
Proteolysis of semax (Met-Glu-His-Phe-Pro-Gly-Pro, Sem) and its analogues ([Ala1]Sem, [Gly1]Sem, [Thr1]Sem, [Trp1]Sem) that are differ from semax in substitution of N-terminal Met residue were studied. It is shown that such replacement changes the ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::153a92e17f322199d4ee66d7b24560be
https://pubmed.ncbi.nlm.nih.gov/22096989
https://pubmed.ncbi.nlm.nih.gov/22096989
Publikováno v:
Bioorganicheskaia khimiia. 36(2)
1,2-Tritium-labeled 3-(O-carboxypropyl)- and 3-(O-carbomethoxypropyl)-oximes of 6alpha-methyl-16alpha,17alpha-cyclohexanopregn-4-ene-3,20-diones were obtained by the homogeneous catalytic hydrogenation of 1,2-dehydroprecursors with gaseous tritium an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e747d8ce5cf4443bd06800717a9eb29
https://pubmed.ncbi.nlm.nih.gov/20531488
https://pubmed.ncbi.nlm.nih.gov/20531488
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 70(5)
The direct radioreceptor assay was used to elucidate the interactions of clinically employed atypical antipsychotic drug olanzapine with the specific binding sites in rat brain membranes. Tritium-labeled olanzapine was obtained by isotope exchange me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2dca6c780121a8149fc8fc6e6c9ef19d
https://pubmed.ncbi.nlm.nih.gov/18074798
https://pubmed.ncbi.nlm.nih.gov/18074798
Autor:
N L, Sheremet, G S, Polunin, A N, Ovchinnikov, A A, Kamenskiĭ, N G, Levitskaia, L A, Andreeva, L Iu, Alfeeva, I Iu, Nagaev
Publikováno v:
Vestnik oftalmologii. 120(6)
In order to substantiate the feasibility of using the "Semax" neuroprotector in the treatment of optic-nerve diseases its pharmacokinetics in the intranasal administration was studied in experiments with rats; besides, the physical-and-chemical prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5957c0c5acb9fb0e96b11959e8042e94
https://pubmed.ncbi.nlm.nih.gov/15678666
https://pubmed.ncbi.nlm.nih.gov/15678666
Autor:
A N, Smirnov, E V, Pokrovskaia, V P, Shevchenko, I Iu, Nagaev, N F, Miasoedov, I S, Levina, L E, Kulikova, A V, Kamernitskiĭ
Publikováno v:
Bioorganicheskaia khimiia. 28(3)
The binding of [3H]progesterone and [3H] 16 alpha,17 alpha-cycloalkanoprogesterones to proteins from rat, rabbit, and human uteri and other organs was studied. We found that 16 alpha,17 alpha-cycloalkanoprogesterone derivatives display affinities for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4932aeac2409d04bc7dc622727f2d00
https://pubmed.ncbi.nlm.nih.gov/12077851
https://pubmed.ncbi.nlm.nih.gov/12077851
Publikováno v:
Bioorganicheskaia khimiia. 28(3)
6-O-(3-Methoxycarbonylpropyl)- and 6-O-(3-carboxypropyl)oximes of 16 alpha,17 alpha-cyclohexanopregn-4-ene-3,6,20-trione labeled by tritium in position 1,2 were synthesized. When using homogenous catalysts, the molar radioactivity of the resulting pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77ff958c23dffd4b5bbe281fb2f9da55
https://pubmed.ncbi.nlm.nih.gov/12077852
https://pubmed.ncbi.nlm.nih.gov/12077852
Publikováno v:
Bioorganicheskaia khimiia. 14(2)
By selecting specific activators of PGF reductase and determining their optimal ratio, we have performed the directed biosynthesis of PGF2 alpha with a 45-50% yield. With the use of [5,6,8,9,11,12,14,15-3H8]arachidonic acid, multiple-labelled PGF2 al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::374520e79942bdbe2c3492b2360d01d2
https://pubmed.ncbi.nlm.nih.gov/2838030
https://pubmed.ncbi.nlm.nih.gov/2838030
Publikováno v:
Bioorganicheskaia khimiia. 14(8)
A method has been developed that makes it possible to obtain [5,6-3H2]PGE1 with a yield of 35% and a molar radioactivity of 1.7-1.8 TBq/mmol. The binding of [5,6-3H2]PGE1 to native platelets proved to be specific, saturating and reversible. It is cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be42ea3b5ac1d166264fdf28b6eb8793
https://pubmed.ncbi.nlm.nih.gov/3219124
https://pubmed.ncbi.nlm.nih.gov/3219124