Zobrazeno 1 - 10
of 46
pro vyhledávání: '"I I Semina"'
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 20-25 (2024)
Relevance. Drug pollution of the environment is a global environmental problem of our time. Increased consumption of medicines directly affects the level of pollution of various ecosystems, including water resources. The insufficient efficiency of ex
Externí odkaz:
https://doaj.org/article/d485f80436f744ee88a5d2c4ff005412
Autor:
V. R. Timergalieva, A. Yu. Sitenkov, A. V. Sitenkova (Bukhovets), E. S. Elizarova, D. S. Gordeeva, I. I. Semina, R. I. Moustafine
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 4, Pp 181-188 (2023)
Introduction. Orally dispersible dosage forms are one of the new trends in the field of drug delivery systems. One type of such dosage forms is oral lyophilisates that are obtained by freeze-drying a pre-prepared mixture containing the active pharmac
Externí odkaz:
https://doaj.org/article/b7d7691515fb42caa3a2e817023d6120
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 68-76 (2023)
Relevance. It is known that the existing drug therapy for cognitive disorders is characterized by low rates of efficacy and safety, as well as symptomatic orientation. Therefore, the search for new drugs in this area is an urgent issue, the solution
Externí odkaz:
https://doaj.org/article/798900736e6d4fda80407881dc4be0fb
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 24-32 (2023)
Relevance. Alzheimer's disease (AD) is a neurodegenerative disease, the drug therapy of which can only slow the progression of the disease, due to the variety of existing pathogenetic processes. A possible effective approach to the correction of symp
Externí odkaz:
https://doaj.org/article/992ee75788a84759ae8910658ef45b05
Autor:
I. I. Semina, A. Z. Baichurina, D. O. Nikitin, A. V. Nikitina, R. I. Moustafine, V. V. Khutoryanskiy
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 1, Pp 161-181 (2023)
Introduction. Behavioral methods on laboratory animals are recognized as the main approach in studying the activity of potential psychotropic drugs and allow us to evaluate the main effects of new compounds, increase the possibility of predicting a s
Externí odkaz:
https://doaj.org/article/8ca0b309b87e4ddb85b0d8e4362ae20e
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 10, Iss 4, Pp 117-127 (2021)
Introduction. Intranasal drug delivery from nose-to-brain is one of the promising approaches for the treatment of brain diseases including neurodegenerative diseases, stroke, brain tumors, etc.Text. Delivery of drugs through the nose has a number of
Externí odkaz:
https://doaj.org/article/1ed5a0357b5547c8866e6af1727b15c3
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 10, Iss 4, Pp 117-127 (2021)
Introduction. Intranasal drug delivery from nose-to-brain is one of the promising approaches for the treatment of brain diseases including neurodegenerative diseases, stroke, brain tumors, etc.Text. Delivery of drugs through the nose has a number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ce47b0f6fa309b94672d8029253be3
https://doi.org/10.33380/2305-2066-2021-10-4-117-127
https://doi.org/10.33380/2305-2066-2021-10-4-117-127
Autor:
E V Begichev, N E Tikhonova, A Z Baychurina, D O Nikitin, E V Shilovskaya, I I Semina, A G Ovchinnikova
Publikováno v:
Kazan medical journal. 102:654-662
Aim. To study the indicators of metabolic changes in the blood and brain structures of rats after exposure to hypobaric hypoxia and to determine possible pharmacological approaches to correction these changes. Methods. Hypobaric hypoxia in rats was s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87acbb3e8d29a5483b1e5fc517a65278
https://doi.org/10.17816/kmj2021-654
https://doi.org/10.17816/kmj2021-654
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 57:404-412
One of the most widespread experimental models for studying the development of autism spectrum disorders (ASDs) and methods of their therapy is the valproic acid-induced rodent model. Individuals born to females who received injections of valproic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44316829d6c2626b55c64b4f3081d0b7
https://doi.org/10.1134/s0022093021020198
https://doi.org/10.1134/s0022093021020198
Autor:
R.D. Mukhametshina, Elena Valeeva, A.D. Mukhametshina, A.G. Mukhamedzhanova, O.A. Kravtsova, D.O. Nikitin, I. I. Semina, I.Kh. Valeeva
Publikováno v:
Biomics. 13:1-7
Stress response is a multifactorial condition which is formed under extreme environmental exposure due to various neuroendocrine systems interactions. Dopaminergic system plays a key role in stress response through the dopamine which effect is realiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f03bc4ef482d2023b0e30d90ba7dd73d
https://doi.org/10.31301/2221-6197.bmcs.2021-1
https://doi.org/10.31301/2221-6197.bmcs.2021-1