Zobrazeno 1 - 10
of 40
pro vyhledávání: '"I I Akopova"'
Investigation of Antiviral Activity of Adamantan Boron Derivaties on Pandemic Influenza Virus Models
Autor:
S. G. Markushin, N. A. Kantarov, S. V. Artyushenko, I. I. Akopova, I. B. Koptyaeva, YU. N. Bubnov
Publikováno v:
Антибиотики и Химиотерапия, Vol 56, Iss 5-6, Pp 3-6 (2020)
Comparative investigation of the virus-inhibiting activity of some boron-containing compounds showed that products BG 12 and BG 4 had the highest inhibitory effect on pandemic viruses. The minimum inhibitory concentration (MIC) of the products was 0.
Externí odkaz:
https://doaj.org/article/aac65931c97f4a5099d24b779757dd88
Autor:
V. Yu. Kost, O. A. Sukhova, I. I. Akopova, E. O. Gorbacheva, K. V. Lisovskaya, A. A. Rtishchev, S. G. Markushin
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 6, Pp 21-29 (2019)
Aim. Study of changes in the phenotypic characteristics of the virulent A/WSN/33 (H1N1) strain of influenza A virus under the influence of the inclusion of site-specific mutations in the PB1-gene of this strain.Materials and methods. Using a two-step
Externí odkaz:
https://doaj.org/article/7762455f28054d108140b6358d496b16
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 2, Pp 68-76 (2019)
Aim. Study of biological properties of attenuated variants of the virulent A/WSN/33 strain of influenza virus, obtained by the site-specific mutagenesis of PB2-gene. Materials and methods. Site-specific mutants of A/WSN/33 of influenza virus, having
Externí odkaz:
https://doaj.org/article/76ab6fd5ad0c4a2ba9e1de153c1f52e7
Autor:
A. A. Rtischev, R. R. Mintaev, V. Yu. Kost, I. B. Koptyaeva, I. I. Akopova, K. V. Lisovskaya, S. G. Markushin
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 2, Pp 45-53 (2017)
Aim. Study the possibility of obtaining attenuated variants of influenza virus by including specially selected site-specific mutations into a conservative sequence of PA-gene (terminal segment of COOH-domain of the PA-gene) of a virulent strain. Mate
Externí odkaz:
https://doaj.org/article/baff44e378524d9ab29e8b874d9e4f1d
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 92, Iss 5, Pp 27-32 (2015)
Aim. Study of ts, ca, att phenotype, immunogenicity and protective effectiveness of reas-sortants, obtained by a way of recombination of a new influenza cold-adapted (ca) strain donor of attenuation A/Krasnodar/101/35/59 (H2N2) and virulent strain of
Externí odkaz:
https://doaj.org/article/bb04b7e363fe47c686a1dbc23b735d5f
Autor:
S. G. Markushin, I. I. Akopova, Inesa V. Blagodatskikh, S. N. Kulikov, A. V. Muranov, Vladimir E. Tikhonov, Igor A. Yamskov, Evgeniya A. Bezrodnykh
Publikováno v:
Applied Biochemistry and Microbiology. 54:512-517
The hemostatic and immunostimulating activity and cytotoxicity were determined for a number of chitosans differing in molecular weight (from 3 to 510 kDa) and degree of acetylation (from 1 to 25 mol%) that were used as adjuvants in inactivated poliom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73cf71a42af0bb05abe374f3b86e255f
https://doi.org/10.1134/s0003683818050149
https://doi.org/10.1134/s0003683818050149
Autor:
R R Mintaev, L B Koptyaeva, V Yu Kost, A A Rtischev, I I Akopova, K V Lisovskaya, S.G. Markushin
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 2, Pp 45-53 (2017)
Aim. Study the possibility of obtaining attenuated variants of influenza virus by including specially selected site-specific mutations into a conservative sequence of PA-gene (terminal segment of COOH-domain of the PA-gene) of a virulent strain. Mate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba8e516d31fdc690599883df046cdee
https://doi.org/10.36233/0372-9311-2017-2-45-53
https://doi.org/10.36233/0372-9311-2017-2-45-53
Autor:
A A, Rtischev, R R, Mintaev, V Yu, Kost, L B, Koptyaeva, I I, Akopova, K V, Lisovskaya, S G, Markushin
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (2)
Study the possibility of obtaining attenuated variants of influenza virus by including specially selected site-specific mutations into a conservative sequence of PA-gene (terminal segment of COOH-domain of the PA-gene) of a virulent strain.A/ WSN/33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5da6dd93668a8f17f11d0763399c5629
https://pubmed.ncbi.nlm.nih.gov/30695536
https://pubmed.ncbi.nlm.nih.gov/30695536
Autor:
Koptiaeva Ib, Markushin Sg, E. A. Nechaeva, Y. Z. Ghendon, I. I. Akopova, T.D. Kolokoltseva, Radaeva If, L.A. Mazurkova
Publikováno v:
Vaccine. 23:4678-4684
Optimal conditions are determined for growing cold-adapted reassortant strains of a live influenza vaccine in MDCK cell line cultivated in a fermenter with a serum-free medium and microcarriers. The studied MDCK cell line meet all national and WHO re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4006cfc630b9ae234659a81818dacc10
https://doi.org/10.1016/j.vaccine.2005.04.039
https://doi.org/10.1016/j.vaccine.2005.04.039
Publikováno v:
Voprosy virusologii. 58(1)
Cold-adapted (CA) strains A/Krasnodar/35 and B/Victoria/63 were isolated using passages of A/Krasnodar/101/59 and B/Victoria/2/87 wild type strains at low temperatures. The resulting CA strains possessed TS and CA phenotypes and had a reduced ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f646ff7c5951825de56320a2af8ed7ab
https://pubmed.ncbi.nlm.nih.gov/23785755
https://pubmed.ncbi.nlm.nih.gov/23785755