Zobrazeno 1 - 10
of 74
pro vyhledávání: '"I I, Bykov"'
Autor:
A. F. Chernousov, T. V. Khorobrykh, I. I. Bykov, M. V. Nemtsov, A. A. Udilova, A. B. Bekshokov
Publikováno v:
Сеченовский вестник, Vol 12, Iss 2, Pp 21-26 (2022)
The article presents the results of many years work carried out at the Department of Surgery of the I.M. Sechenov First MSMU in one of the priority areas — the study of molecular-genetic markers. The possibilities of use of the molecular-genetic ma
Externí odkaz:
https://doaj.org/article/71b1d5dc15e744ed8362092d3b776e2a
Autor:
I. I. Bykov
Publikováno v:
Сеченовский вестник, Vol 0, Iss 1, Pp 59-66 (2022)
This article deals with the problem of determining of surgical treatment of the stomach cancer patients.
Externí odkaz:
https://doaj.org/article/642577d06974459a85c45e49ddfa4616
Autor:
Dmitry S. Mikhaylenko, Andrey A. Zamyatnin, Marina V. Nemtsova, Ekaterina B. Kuznetsova, I. I. Bykov
Publikováno v:
Biochemistry (Moscow). 85:735-748
Main factors involved in carcinogenesis are associated with somatic mutations in oncogenes and tumor suppressor genes representing changes in the DNA nucleotide sequence. Epigenetic changes, such as aberrant DNA methylation, modifications of histone
Autor:
Vladimir V Strelnikov, Alexander S Tanas, Dmitry S. Mikhaylenko, T. V. Khorobrykh, Marina V. Nemtsova, Ekaterina B. Kuznetsova, Irina V. Bure, A.I. Kalinkin, Ekaterina A. Alekseeva, I. I. Bykov
Publikováno v:
Cancers, Vol 13, Iss 4586, p 4586 (2021)
Cancers
Volume 13
Issue 18
Cancers
Volume 13
Issue 18
Simple Summary Epigenetic mechanisms, such as DNA methylation/demethylation, covalent modifications of histone proteins, and chromatin remodeling, create specific patterns of gene expression. Epigenetic deregulations are associated with oncogenesis,
Autor:
Vladimir V Strelnikov, Ekaterina A. Alekseeva, Alexander S Tanas, Dmitry V. Zaletaev, Irina V. Bure, I. I. Bykov, Dmitry S. Mikhaylenko, Ekaterina B. Kuznetsova, T. V. Khorobrykh, Sergey I. Kutsev, A.I. Kalinkin, Marina V. Nemtsova
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Somatic mutation profiling in gastric cancer (GC) enables main driver mutations to be identified and their clinical and prognostic value to be evaluated. We investigated 77 tumour samples of GC by next-generation sequencing (NGS) with the Ion AmpliSe
Autor:
A.I. Kalinkin, Vladimir V Strelnikov, Marina V. Nemtsova, Ekaterina B. Kuznetsova, I. I. Bykov, I.U. Efimova, E.A. Alekseeva, E. Ignatova, Alexander S Tanas, A. Alakunov
Publikováno v:
Annals of Oncology. 30:v316
Background Gastric cancer is the fifth most common malignancy in the world and the third leading cause of cancer death. Approximately 1–3% of gastric cancers are hereditary. Mutations of CDH1,the gene encoding E-cadherin, are the most common germl
Autor:
Viktoria V Rudenko, Tatiana V Kchorobrich, Alexander S Tanas, Dmitry V. Zaletaev, Marina V. Nemtsova, George E. Barreto, Gjumrakch Aliev, Yi Li, Vadim V. Tarasov, Vladimir V Strelnikov, I. I. Bykov, A.I. Glukhov
Publikováno v:
Current Genomics
Introduction We have investigated aberrant methylation of genes CDH1, RASSF1A, MLH1, N33, DAPK, expression of genes hTERT, MMP7, MMP9, BIRC5 (survivin), PTGS2, and activity of telomerase of 106 gastric tumor samples obtained intra-operatively and 53
Autor:
Vladimir V Strelnikov, Marina V. Nemtsova, Ekaterina B. Kuznetsova, Dmitry V. Zaletaev, A.I. Kalinkin, K. Kirillova, T. Kchorobryh, I. I. Bykov, E.A. Alekseeva, Alexander S Tanas
Publikováno v:
Annals of Oncology. 30:iv15
Publikováno v:
Molecular Biology. 47:727-732
Allelic imbalance and microsatellite instability in operating materials from 78 patients with gastric cancer was studied. Microsatellite polymorphism for 17p13.1 (TP53), 1p36.1 (RUNX3), 16p22 (CDH1), and MH (BAT26) was determined in tumor and adjacen
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 5:188-192
Telomerase activity was examined in tissue specimens from patients with gastric adenocarcinomas and gastric lymphoma using a modified TRAP (telomeric repeat amplification protocol) assay. Telomerase activity was found in 16 of 18 (89%) patients with