Zobrazeno 1 - 10
of 70
pro vyhledávání: '"I Hare"'
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background The tumour stroma -or tumour microenvironment- is an important constituent of solid cancers and it is thought to be one of the main obstacles to quantitative translation of drug activity between the preclinical and clinical phases
Externí odkaz:
https://doaj.org/article/09e9c22f1aed4a779fe1d738a5c00730
Autor:
Hare, Steven R, Williams, Peter G, Jordán, Claudio Castillo, Hamer, Paul A, Hampton, William J, Lehodey, Patrick, Macdonald, Jed, Scott, Robert D, Phillips, Joe Scutt, Senina, Inna, Pilling, Graham M, I Hare, Williams, Steven R Ii, Gregory, Peter, Iii Castillo Jordán, Hamer, Claudio D Iv, Hampton, Paul A V, Lehodey, John Vi, P Vii, J Macdonald, Viii Scott, Phillips, Robert D Ix Scutt, Jordán, Castillo, C Hamer, Hampton W J Lehodey, Scutt Phillips
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15634ceb0c5cb536802bace8101dc6e8
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004550 (2015)
Xenografts--as simplified animal models of cancer-differ substantially in vasculature and stromal architecture when compared to clinical tumours. This makes mathematical model-based predictions of clinical outcome challenging. Our objective is to fur
Externí odkaz:
https://doaj.org/article/8bf1e76393de4797b3229a1ebff6d530
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 17, Iss 1, Pp 1-1 (2017)
Externí odkaz:
https://doaj.org/article/6530b3686e26425ebae4d1875e0c49e8
Autor:
Hare, Steven R, Williams, Peter G, Jord��n, Claudio Castillo, Hamer, Paul A, Hampton, William J, Scott, Robert D, Pilling, Graham M, I Hare, Williams, Steven R Ii, Gregory, Peter, Iii Castillo Jord��n, Hamer, Claudio D Iv, Hampton, Paul A V, Scott, John Vi, Vii, Robert D, Pilling, Graham Viii, Jord��n, Castillo, C Hamer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f326484a656c6202638f1be8e262b05
Autor:
Jennifer I Hare, Robert W Neijzen, Malathi Anantha, Nancy Dos Santos, Natashia Harasym, Murray S Webb, Theresa M Allen, Marcel B Bally, Dawn N Waterhouse
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62349 (2013)
To investigate the use of liposomal irinotecan (Irinophore C™) plus or minus 5-fluorouracil (5-FU) for the treatment of colorectal cancer.The effect of irinotecan (IRI) and/or 5-FU exposure times on cytotoxicity was assessed in vitro against HT-29
Externí odkaz:
https://doaj.org/article/d91877b9f732401faa35bb016a25a1b5
Autor:
Marianne Ashford, Simon T. Barry, Kevin Treacher, Michael J. Waring, Cameron Alexander, Paul D. Kemmitt, Richard M. England, Jennifer I. Hare
Publikováno v:
Polymer Chemistry. 7:4609-4617
When considering the design of an advanced drug delivery system, a common desirable attribute is to have a prolonged residence time in blood circulation so that accumulation and localised payload release may occur at the site of interest (e.g. a tumo
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 11:1247-1252
It is challenging to evaluate how tumour pathophysiology influences nanomedicine therapeutic effect; however, this is a key question in drug delivery. An advanced analytical method was developed to quantify the spatial distribution of drug-induced ef
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ross A, Little, Hervé, Barjat, Jennifer I, Hare, Mary, Jenner, Yvonne, Watson, Susan, Cheung, Katherine, Holliday, Weijuan, Zhang, James P B, O'Connor, Simon T, Barry, Sanyogitta, Puri, Geoffrey J M, Parker, John C, Waterton
Publikováno v:
Magnetic resonance imaging. 46
Solid tumours exhibit enhanced vessel permeability and fenestrated endothelium to varying degree, but it is unknown how this varies in patients between and within tumour types. Dynamic contrast-enhanced (DCE) MRI provides a measure of perfusion and p