Recurrent disease detection after resection of pancreatic ductal adenocarcinoma using a recurrence-focused surveillance strategy (RADAR-PANC): protocol of an international randomized controlled trial according to the Trials within Cohorts design

Autor: L. A. Daamen, I. W. J. M. van Goor, V. P. Groot, P. C. M. Andel, L. A. A. Brosens, O. R. Busch, G. A. Cirkel, N. Haj Mohammad, H. D. Heerkens, I. H. J. T. de Hingh, F. Hoogwater, H. W. M. van Laarhoven, M. Los, G. J. Meijer, V. E. de Meijer, R. Pande, K. J. Roberts, J. Stoker, M. W. J. Stommel, G. van Tienhoven, R. C. Verdonk, H. M. Verkooijen, F. J. Wessels, J. W. Wilmink, M. G. Besselink, H. C. van Santvoort, M. P. W. Intven, I. Q. Molenaar, for the Dutch Pancreatic Cancer Group

Publikováno v: Trials, Vol 25, Iss 1, Pp 1-18 (2024)

Abstract Background Disease recurrence remains one of the biggest concerns in patients after resection of pancreatic ductal adenocarcinoma (PDAC). Despite (neo)adjuvant systemic therapy, most patients experience local and/or distant PDAC recurrence w

Externí odkaz: https://doaj.org/article/ba5d1663657942199349b99fc6296573

Role Of Ovarian Metastases In Colorectal Cancer (ROMIC): a Dutch study protocol to evaluate the effect of prophylactic salpingo-oophorectomy in postmenopausal women

Autor: R. Van der Meer, I. H. J. T. de Hingh, J. G. Bloemen, L. Janssen, R. M. H. Roumen

Publikováno v: BMC Women's Health, Vol 22, Iss 1, Pp 1-10 (2022)

Abstract Background The mean incidence of ovarian metastases (OM) in patients with colorectal cancer (CRC) is 3.4%. The 5-year survival of these patients, even when operated with curative intent, is remarkably low. The lifetime risk of ovarian cancer

Externí odkaz: https://doaj.org/article/338f0c84318f4c49916fe1a188c5fed6

Total neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy and adjuvant gemcitabine for resectable and borderline resectable pancreatic cancer (PREOPANC-2 trial): study protocol for a nationwide multicenter randomized controlled trial

Autor: Q. P. Janssen, J. L. van Dam, B. A. Bonsing, H. Bos, K. P. Bosscha, P. P. L. O. Coene, C. H. J. van Eijck, I. H. J. T. de Hingh, T. M. Karsten, M. B. van der Kolk, G. A. Patijn, M. S. L. Liem, H. C. van Santvoort, O. J. L. Loosveld, J. de Vos-Geelen, B. M. Zonderhuis, M. Y. V. Homs, G. van Tienhoven, M. G. Besselink, J. W. Wilmink, B. Groot Koerkamp, for the Dutch Pancreatic Cancer Group

Publikováno v: BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)

Abstract Background Neoadjuvant therapy has several potential advantages over upfront surgery in patients with localized pancreatic cancer; more patients receive systemic treatment, fewer patients undergo futile surgery, and R0 resection rates are hi

Externí odkaz: https://doaj.org/article/c4666a70be2f4516b363089ddb9e6b2b

Ovarian metastases in young women with colorectal cancer: a retrospective multicenter cohort study

Autor: R, van der Meer, C, Bakkers, J A, Wegdam, T, Lettinga, E G, Boerma, F, Aarts, I H J T, de Hingh, R M H, Roumen

Publikováno v: International journal of colorectal disease. 37(8)

Previous studies indicated that approximately 3.4% of female colorectal cancer (CRC) patients are at increased risk of developing ovarian metastases (OM). It has been suggested that young women more frequently develop this form of metastatic disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::442c6225cc5c914944e07c3904952598
https://pubmed.ncbi.nlm.nih.gov/35857105

Adhesion formation after surgery for locally advanced colonic cancer in the COLOPEC trial

Autor: E S, Zwanenburg, D D, Wisselink, C E L, Klaver, A R M, Brandt, A J A, Bremers, J W A, Burger, W M U, van Grevenstein, P H J, Hemmer, I H J T, de Hingh, N F M, Kok, M J, Wiezer, J B, Tuynman, P J, Tanis, D D E, Zimmerman

Publikováno v: Zwanenburg, E S, Wisselink, D D, Klaver, C E L, Brandt, A R M, Bremers, A J A, Burger, J W A, van Grevenstein, W M U, Hemmer, P H J, de Hingh, I H J T, Kok, N F M, Wiezer, M J, Tuynman, J B, Tanis, P J & COLOPEC trial collaborators 2022, ' Adhesion formation after surgery for locally advanced colonic cancer in the COLOPEC trial ', The British journal of surgery, vol. 109, no. 4, pp. 315-318 . https://doi.org/10.1093/bjs/znab467
The British journal of surgery, 109(4), 315-318. John Wiley and Sons Ltd
British Journal of Surgery, 109(4), 315-318. Wiley
British Journal of Surgery, 109, 315-318
British Journal of Surgery, 109, 4, pp. 315-318
British Journal of Surgery, 109(4), 315-318. OXFORD UNIV PRESS

This study investigated the impact of laparoscopic or open resection of locally advanced colonic cancer on the incidence and severity of adhesions evaluated by laparoscopy at 18 months, primarily intended to evaluate peritoneal recurrence. Open surge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdaca371cff3e2b78f556b793ad9f8e3
https://research.vumc.nl/en/publications/5404d3aa-ff7e-4663-bf8a-922fe0bd8328