Výsledky vyhledávání - "I F, Nikiforova"

Loss of heterozygosity at chromosome 17p is associated with HER-2 amplification and lack of nodal involvement in breast cancer

Autor: P G, Knyazev, E N, Imyanitov, O I, Chernitsa, I F, Nikiforova

Publikováno v: International Journal of Cancer. 53:11-16

Sixty DNA samples from breast carcinoma (BC) patients were analyzed by Southern blot to examine certain oncogene and anti-oncogene alterations. Amplification of the HER-2 oncogene was detected in 15 tumours (25%), c-myc in 2 (3%) only and HER-1 in no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ded1da5e9d3fac44e1d58731894facd
https://doi.org/10.1002/ijc.2910530104

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[Damage to the transforming growth factor TGF-beta type II receptor gene and microsatellite instability in carcinoma cells of the gastrointestinal tract]

Autor: O A, Vostriukhina, I F, Nikiforova, T A, Shtam, S L, Kantorov, V K, Kovalev, S V, Vasil'ev, K M, Pozharisskiī, V A, Lantsov

Publikováno v: Voprosy onkologii. 44(6)

In order to compare the frequency of damage to the transforming growth factor TGF-beta receptor type II gene (RII gene) and microsatellite instability (MIN) in oncogenesis of sporadic and hereditary cancer of gastrointestinal tract (GIT), 4 groups of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cfdb86843cc9df2e6728199a7c92587d
https://pubmed.ncbi.nlm.nih.gov/10087960

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[Microsatellite instability of genome in cells of sporadic and hereditary carcinoma of the gastrointestinal tract]

Autor: O A, Vostriukhina, I F, Nikiforova, T A, Shtam, S L, Kantorov, K Iu, Tutaev, A R, Shumakov, S V, Komissarova, V P, Kalinovskiĭ, S V, Vasil'ev, V K, Kovalev

Publikováno v: Voprosy onkologii. 44(5)

Microsatellite instability (MIN) of human genome, i.e. instability of very short (1-5 nt) DNA tandem repeats, points to a deficiency in the mismatch repair system (MMR). To investigate the role of MMR in sporadic and hereditary carcinogenesis in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4baa076130e8c2b5e7854455795d781c
https://pubmed.ncbi.nlm.nih.gov/9884704

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[Multiple drug resistance in yeasts and its effect on stability and karyotype of transformants]

Autor: O V, Nevzgliadova, S G, Davydenko, I F, Nikiforova, A V, Shmelev, T R, Soĭdla

Publikováno v: Molekuliarnaia biologiia. 29(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::35e0ddf696dd0f26d5e55552551e0d65
https://pubmed.ncbi.nlm.nih.gov/8538609

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[Amplification of the erbb-2 (Her-2/NEU), erbb-1 (HER-1) and c-myc oncogenes is often combined with the deletion of the short arm of chromosome 17 in human carcinoma]

Autor: E N, Imianitov, O I, Chernitsa, I F, Nikiforova, O M, Serova, S I, Sokolov, O Iu, Laur, A V, Togo, P G, Kniazev

Publikováno v: Molekuliarnaia biologiia. 27(4)

Amplification of oncogenes erbb-2, erbb-1, c-myc and losses of heterozygosity (LOH) at chromosomes 11p (probe hras-1), 17p (probe ynz-22) and 17q (probe thh-59) were studied in 165 human tumours (60 breast, 22 ovary, 40 colorectal, 23 lung, and 20 th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e43177b3ccffc42edcdc5917aae1082
https://pubmed.ncbi.nlm.nih.gov/8103188

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[Complex characteristics of the alterations of oncogenes HER-2/ERBB-2, HER-1/ERBB-1, HRAS-1, C-MYC and antioncogenes p53, RB1, as well as deletions of loci of chromosome 17 in colon carcinoma]

Autor: P G, Kniazev, E N, Imianitov, O I, Chernitsa, I F, Nikiforova, V I, Babenko, S, Bruderliaĭn, O V, Plutalo, A I, Kuz'min, O K, Kaboev, Iu A, Berlin

Publikováno v: Molekuliarnaia biologiia. 26(5)

Abnormalities of some oncogenes, antioncogenes and losses of heterozygosity (LOH) of chromosome 11p, 17p, and 17q in colorectal carcinomas (CC) was studied. Amplification of ERBB-1/HER-1 oncogene was detected in 2 of 56 cases; ERBB-2/HER-2- in 4 of 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::692d3999421f0540db31acefb2305613
https://pubmed.ncbi.nlm.nih.gov/1470178

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[The search for amplification of the ERBB-2 oncogene in human tumors]

Autor: E N, Imianitov, O I, Chernitsa, I F, Nikiforova, K V, Titov, K P, Khanson, P G, Kniazev

Publikováno v: Voprosy onkologii. 38(6)

The occurrence of ERBB-2 (HER-2/NEU) oncogene amplification was studied in 203 DNA samples obtained from 175 cancer patients. Amplification of ERBB-2 oncogene was established in 14 out of 63 (22%) patients with breast cancer, 1 out of 23 cases of ova

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https://pubmed.ncbi.nlm.nih.gov/1300765

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Molecular Mechanism of Alteration of H-RasI Oncogene in Human Breast Carcinomas: G to T Transversion in 12th Codon of the Undeleted Allele in the Case of the Loss of the Other Gene Allele

Autor: I. F. Nikiforova, P. G. Knyazev, V. I. Babenko, O. V. Plutalov, U. A. Berlin, O. M. Serova, A. A. Goltzov, G. F. Pluzhnikova, E. I. Scwartz

Publikováno v: Modern Trends in Human Leukemia IX ISBN: 9783540543602

It is widely accepted that tumor development and progression are due to illegitimate activation of cellular oncogenes by point mutation, retroviral insertion, chromosomal translocation and amplification or deletion of the gene [1–3]. Nonrandom dele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99e839df1d55d9a221f00c1e854b690c
https://doi.org/10.1007/978-3-642-76829-3_40

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[The role of the constitutional features and rearrangement of the H-ras 1 oncogene in the development of human lung cancer]

Autor: I F, Nikiforova, M G, Maksimishina, V G, Lemekhov, P G, Kniazev

Publikováno v: Voprosy meditsinskoi khimii. 37(6)

Length polymorphism of restriction fragments of oncogene HRASI was studied in 52 patients with lung cancer as compared with corresponding normal tissues and leukocytes of these patients and of healthy volunteers. Enhanced frequency of one of main all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::235cbebae05493cc614b85b0e959770d
https://pubmed.ncbi.nlm.nih.gov/1687495

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[An increased frequency of allele A6 of the proto-oncogene HRAS1 in cancer patients]

Autor: I F, Nikiforova, G F, Pluzhnikova, O M, Serova, P G, Kniazev

Publikováno v: Voprosy onkologii. 37(6)

Size and frequency of rare alleles of HRAS1 protooncogene were studied in 258 patients with various neoplasms and 32 healthy donors of the northwestern region of the USSR. Literature data on distribution of rare alleles of certain size in sick and he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c8fe48c7e516812e87baa447c099c42
https://pubmed.ncbi.nlm.nih.gov/1843147

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