Zobrazeno 1 - 10
of 185
pro vyhledávání: '"I F, McKenzie"'
Publikováno v:
The Journal of Immunology. 150:1794-1803
Fc gamma RII is a low affinity FcR for IgG with two Ig-like extracellular domains (D1 gamma and D2 gamma), a transmembrane domain, and a cytoplasmic domain. The production, characterization, and epitope analysis of four anti-human Fc gamma RII mAb (8
Publikováno v:
The Journal of Immunology. 149:2615-2618
The Thb locus is responsible for the expression of 15-kDa phosphatidyl inositol anchored molecules (ThB) on murine thymocytes and B cells. Thb expression as detected with mAb is polymorphic on B cells with two alleles, Thbh and Thb1 responsible for t
Publikováno v:
The Journal of Immunology. 149:1636-1641
We describe the production and characterization of a mouse mAb, S-450-33.2, recognizing the Ly-9.2 specificity. This mAb was used to purify Ly-9 molecules from lymphoid cell lines, and the amino-terminal amino acids were determined. The mAb was also
Publikováno v:
The Journal of Immunology. 148:1570-1575
We describe the isolation and characterization of the gene encoding the mouse high affinity Fc receptor Fc gamma RI. Using a mouse cDNA Fc gamma RI probe four unique overlapping genomic clones were isolated and were found to encode the entire 9 kb of
Publikováno v:
The Journal of Immunology. 147:1863-1868
Chimeric Fc gamma R have been generated between the mouse high affinity receptor for IgG (Fc gamma RI) and the low affinity receptor for IgG (Fc gamma RII) by exchanging the first two domains of the three-domain extracellular structure of Fc gamma RI
Publikováno v:
The Journal of Immunology. 146:369-376
We have isolated and deduced the structure of the beta Fc gamma RII gene from the mouse. This gene spans approximately 18 kb of DNA; the structure and nucleotide sequence has been determined and potential regulatory sites identified. This gene is com
Publikováno v:
Transplantation. 72(6)
We previously reported the induction of transplantation tolerance by a modified wide field method of pretransplant total lymphoid irradiation (TLI), cumulative dose 800 cGy, given as 80 or 100 cGy fractions twice/week, in approximately one-third of c
Autor:
S, Nozawa, P X, Xing, G D, Wu, E, Gochi, M, Kearns-Jonker, J, Swensson, V A, Starnes, M S, Sandrin, I F, McKenzie, D V, Cramer
Publikováno v:
Transplantation. 72(1)
Natural antibodies that react with galactose-alpha(1,3)galactose [galalpha(1,3)gal] carbohydrate epitopes exist in humans and Old World primates because of the inactivation of the alpha1,3-galactosyltransferase (alpha1,3GT) gene in these species and
Publikováno v:
Current opinion in molecular therapeutics. 2(1)
The major histocompatibility complex molecules bind and present short antigenic peptide fragments on the surface of antigen presenting cells to T-cell receptors. Recognition of peptide-MHC by cytotoxic T-cells initiates a cascade of signals to T-cell
Publikováno v:
Current opinion in molecular therapeutics. 1(1)
The development of an effective immunotherapeutic approach to cancer is now a major focus of research, and despite impressive progress over the last 10 years there are still many hurdles to overcome to elicit an effective immune response which will t