Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the ADRB1 Arg389Arg Genotype

Autor: Jonathan P. Piccini, Christopher Dufton, Ian A. Carroll, Jeff S. Healey, William T. Abraham, Yaariv Khaykin, Ryan Aleong, Steven K. Krueger, William H. Sauer, Stephen B. Wilton, Michiel Rienstra, Dirk J. van Veldhuisen, Inder S. Anand, Michel White, A. John Camm, Paul D. Ziegler, Debra Marshall, Michael R. Bristow, Stuart J. Connolly, F Ayala-Paredes, A Bakbak, ML Bernier, DH Birnie, B Coutu, E Crystal, MW Deyell, KM Dyrda, MC Hartleib, ZW Laksman, P Leong-Sit, CA Morillo, AS Pandey, F Philippon, S Vizel, P Andréka, Z Csanadi, GZ Duray, T Forster, G Kerkovits, B Merkely, AC Nagy, T Simor, D Czarnecka, JD Kasprzak, WJ Musial, G Raczak, J Szachniewicz, JK Wranicz, S Apostolović, S Hinić, V Miloradović, D Simić, GJ Milhous, A Oomen, TJ Romer, LM van Vijk, PB Adamson, JD Allred, N Amjadi, MM Bahu, AJ Bank, AE Berman, MA Bernabei, RS Bhagwat, L Borgatta, AJ Buda, RT Cole, JL Collier, SJ Compton, O Costantini, MR Costanzo, IM Dauber, MP Donahue, I Dor, GF Egnacyzk, EJ Eichhorn, CC Eiswirth, S Emani, GA Ewald, RC Forde-McLean, MD Gelernt, DE Haines, CA Henrikson, JM Herre, B Herweg, L Ilkhanoff, LR Jackson, A Lala, R Lo, B London, BD Lowes, JA Mackall, V Malhotra, FA McGrew, S Murali, A Natale, KR Nilsson, J Okolo, MV Perez, RS Phang, R Ranjan, MY Rashtian, MJ Ross, SM Samii, T Shinn, MB Shoemaker, SA Strickberger, VN Tholakanahalli, A Tzur, PJ Wang, LT Younis

Publikováno v: Circulation. Arrhythmia and Electrophysiology, 14(8):009591. LIPPINCOTT WILLIAMS & WILKINS

Background: Bucindolol is a genetically targeted β-blocker/mild vasodilator with the unique pharmacological properties of sympatholysis and ADRB1 Arg389 receptor inverse agonism. In the GENETIC-AF trial (Genotype-Directed Comparative Effectiveness T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b3b46d4e71ba0e2188b0ff7e480073
https://research.rug.nl/en/publications/e4da658b-c78f-4c9f-a6ea-3c34cd1b9426

Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial

Autor: Erin A Bohula, Benjamin M Scirica, Silvio E Inzucchi, Darren K McGuire, Anthony C Keech, Steven R Smith, Estella Kanevsky, Sabina A Murphy, Lawrence A Leiter, Jamie P Dwyer, Ramon Corbalan, Christian Hamm, Lee Kaplan, Jose Carlos Nicolau, Ton Oude Ophuis, Kausik K Ray, Mikhail Ruda, Jindrich Spinar, Tushar Patel, Wenfeng Miao, Carlos Perdomo, Bruce Francis, Shobha Dhadda, Marc P Bonaca, Christian T Ruff, Marc S Sabatine, Stephen D Wiviott, Silvio Inzucchi, Anthony Keech, Andrew Satlin, Conville Brown, Andrzej Budaj, Jamie Dwyer, Armando Garcia-Castillo, Milan Gupta, Kauski Ray, Neil Weissman, Harvey D White, J Amerena, M Arstall, D Colquhoun, R Jayasinghe, A Lee, R Lehman, R Moses, J Proietto, P Purnell, J Waites, P Blombery, D Cross, M Worthley, M d'Emden, J Selvanayagam, RE Oqueli, A Whelan, P Garrahy, F de Looze, D Ninio, J Horowitz, M William, M Suranyi, G Wittert, M Le May, AS Pandey, S Vizel, R Labonte, Y Beaudry, C Fortin, A Bell, S Kouz, É St-Amour, I Bata, F St Maurice, R Chehayeb, C Constance, G Wong, A Hess, J Liutkus, P Poirier, I Teitelbaum, J Berlingieri, J Cha, M Hartleib, M Heffernan, D Twum-Barima, V Pandith, R Aronson, R Goldenberg, B Ajala, A Jain, S Ross, H Bajaj, H Khandwala, Z Yared, N Gupta, J Bédard, S Wharton, F Blouin, D Savard, D Shukla, J Cobos, G Godoy, L Perez, C Pincetti, V Saavedra Guajardo, P Varleta, C Conejeros, F Lanas, E Bayram Llamas, E Cardona Muñoz, R Garcia, J Garza Ruiz, G Llamas Esperon, E Lopez Rosas, G Melendez Mier, G Ramos, H Hart, D Scott, I Ternouth, J Benatar, J Elliott, R Cutfield, P Manning, M Williams, K Ferrier, R Scott, S Wilson, R Leikis, BK Nirmalaraj, E Krzyżagórska, P Miękus, M Bronisz, E Mirek-Bryniarska, K Łanda, A Stasiewski, T Żechowicz, D Zytkiewicz-Jaruga, J Korecki, M Ogórek, L Pawłowicz, M Piepiorka, J Skierkowska, A Stankiewicz, E Szyprowska, R Witek, A Bochenek, P Kończakowski, Ł Wojnowski, M Wujkowski, K Cymerman, R Korzeniak, P Mąder, B Mikłaszewicz, P Stachlewski, A Goch, W Pomiećko, M Skórski, L Romanowski, K Jusiak, E Laskowska-Derlaga, R Bijata-Bronisz, J Kaźmierczak, R Goldberg, D Henderson, E Korban, K Rohr, E Claxton, R Weiss, D Angiolillo, F Boccalandro, K Chu, E Thorn, P Randhawa, N Singh, G Bittar, T Guarnieri, S Saeed, S Sharma, M Shepard, W French, P Desai, R Bernstein, W Rogers, R Singal, R Schneider, J Shanes, S Ong, J Condit, S Donahoe, D Brill, D Einhorn, R Ebrahimi, A Labroo, R Graf, J Scott, J Hoekstra, P Jetty, G Luckasen, P O'Donnell, W Gonte, D Pomposini, M Quadrel, M Koren, D Schlager, E Schramm, D Singal, S Lupovitch, A Soni, P Seigel, J Roberts, J Soufer, S Reza, E Quinlan, T Moretto, B First, M Khan, S Chilka, H Colfer, A Teklinski, K Wallace-Wilding, H Ellison, D Muse, S Aronoff, A Higgins, S Patel, V Elinoff, A Karim, V Awasty, R Chuang, H Roseman, P Dugano-Daphnis, M Albert, K Sheikh, H Bays, S Kaster, M Goldstein, D Rubino, G Calatayud, H Snyder, T Williams, K Hershon, M Hagan, S Isserman, B Kahn, J Anderson, MP Gimness, A Raisinghani, M Christina, M Raikhel, E Gillespie, E Portnay, M Heiman, M Qureshi, J Lee, R Blonder, F Cucher, G Miller, D Kotlaba, G Cornett, J Beavins, C Augenbraun, S Reinhardt, A Bartkowiak, A Salacata, T Blevins, S Benjamin, J Diener, W George, B Barker, R Richwine, D Baldari, A Alfieri, A Barreto, L Zhang, R Shah, E Hendrix, V Subramaniyam, S Hurley, M Lillestol, M O'Donoghue, S Shayani, E Ryan, R Call, L Zemel, A Chang, A Kivitz, B Freyne, V Bland, K Shore, E Mostel, E Uzoaga, N Andrawis, N Gabra, A Ghitis, K Sabatino, D Browder, S Varma, S Smith, R Fink, GR Aycock, WD Doty, T Alfonso, S Eshaghian, R Karlsberg, S Zarich, C Landau, M McKenzie, R Krause, W Davis, T Haddad, S Voyce, C Alford, J LeDoux, D O'Dea, J Park, V Aroda, A Getaneh, B Graham, R Bhagwat, D Korn, G Ruoff, A Wiseman, I Lieber, J Fialkow, JM Gonzalez-Campoy, C Bayron, B Bertolet, J Lash, C Gerrish, D Robertson, J Rosenfeld, M Seidner, J Agaiby, J Silverfield, D Sugimoto, B Lubin, M Alhaddad, H Lui, G Lakin, S Chokshi, D Donovan, W Felten, S Minton, C Kimmelstiel, J Kuvin, C Still, W Byars, J Talano, V Desai, AJ Bradley, S Baker, M Chane, A Mercado, S Baron, B Harris, N Mayer, M Concha, K Carr, L Chaykin, J Willis, A Clay, E Fenstad, J Furda, P Peterson, M Chang, L Aronne, D Jones, R Prashad, M Benson, R Stegemoller, K Longshaw, J Saleh, W Jennings, R Detweiler, D Viswanath, R Patel, S Lederman, D Weinstein, R Korabathina, V Singh, J Rosen, R Estevez, P Levin, R McNeill, V Kalen, J Reed, R Ashley, L Herman, Y Tsai, D Kayne, A White, I Hussain, L Tami, K Cohen, J Robinson, D Fuchs-Ertman, G Platt, L Belardo, R Reddy, C Rosendorff, F Saba, S Powell, K Anderson, M Abidi, S Rezkalla, A Paraschos, J Wilson, M Moursi, A Shah, V Nadar, L Stonesifer, M Bialow, K Cannon, W Ellison, M Stedman, J Brown, W Harper, KJ Lucas, M DiGiovanna, H Rodbard, M Biscoveanu, C Davis, J Hall, R Littlefield, T Gorman, D Kereiakes, FM Chang, H Tatu, D Cheung, J Kaine, T Knutson, T Logemann, G Pueblitz, J Bianco, B Henson, M Neustel, M Gelernt, W Nelson, K Moriarty, G Lefebvre, K Maw, L Rink, P Behn, H Studdard, G Argoud, T O'Connor, P Krichmar, G Raad, J Pereles-Ortiz, C Sorli, A Cohen, K Pettis, B Cavanaugh, C Phillips, J Wahlen, D Radin, J Rider, E Kosinski, W Leimbach, A Odhav, J Hakas, A Tan, M Howell, D Wombolt, N Fishman, P Shah, P Wylie, C Arauz-Pacheco, A Cavale, A George, R Kroll, J Krantzler, N Tahirkheli, M Jabro, M Newell, P Mullen, N Gencheff, J Meli, K Vora, L Kotek, K Pyzdrowski, H Paez, J Moran, A Tannenbaum, K Deck, R Busch, L Levinson, M Azizad, J Whitaker, B Fox, C Huffman, M Ashraf, J Diogo, R Kushner, J Tallet, V Channamsetty, D Suh, M Atieh, J Navas, V Young, S Shaw, I Dor, B Duffy, P Rubin, D Lewis, W Kaye, R Benton, J Burbano, D Hotchkiss, A Magno, A Alberton, J Collins, O Alvarado, M Stich, S Mahal, J Liu, M Hong, J Dy, B Block, J Lamantia, J Pritchard, M Davis, S Srivastava, S Bilazarian, R Rosario, M McCartney, V Blumberg, R Rajan, E Martin, S Wright, C Brinson, J Johnston, M Graves, M Dominguez, W McKenzie, R Abadier, C Tran, R Castello, E Morawski, J White, F Morris, A Perez, P Trueba, M Sanchez, J Andersen, R Kastelic, J Khan, H Rodriguez, W Izquierdo, A Matias, L Essandoh, C Ince

Publikováno v: Lancet (London, England). 392(10161)

BACKGROUND: There is a direct relationship between bodyweight and risk of diabetes. Lorcaserin, a selective serotonin 2C receptor agonist that suppresses appetite, has been shown to facilitate sustained weight loss in obese or overweight patients. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a4e189e200fa6beb5d4585cfb676ca
https://pubmed.ncbi.nlm.nih.gov/30740430

Simulation of performance of centrifugal circulators with vaneless diffuser for GCR applications

Autor: I. Dor, N. Tauveron

Publikováno v: Nuclear Engineering and Design. 240:2421-2435

In the frame of the international forum GenIV, CEA has selected various innovative concepts of gas-cooled nuclear reactor. Thermal hydraulic performances are a key issue for the design. For transient conditions and decay heat removal situations, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aaafa79fda5acb992a24f8cd607d1a88
https://doi.org/10.1016/j.nucengdes.2010.05.066

Développements en double phase. 3D-Poreux de CATHARE

Autor: D. Bestion, I. Dor, M. Chandesris, G. Serre, M. Valette

Publikováno v: Thermohydraulique des assemblages combustibles des réacteurs à eau légère.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::106acd227b3e5f9810d1a6a186b4cbeb
https://doi.org/10.1051/jtsfen/2013the08

Study of Nitrogen Injection to Enhance Forced Convection for GFR Demonstrator ALLEGRO

Autor: I. Dor, Fabrice Bentivoglio, Nicolas Tauveron

Publikováno v: ASME 2010 Power Conference.

In the frame of the international forum GenIV, the Gas Fast Reactor is considered as a promising concept, combining the benefits of fast spectrum and high temperature, using helium as coolant. In the Gas Fast Reactor development plan, ALLEGRO is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59fa0dc9ac65f5b7cce89449482cdbc3
https://doi.org/10.1115/power2010-27137