Výsledky vyhledávání - "I Demeestere"

Akademický článek

Ovarian toxicity of carboplatin and paclitaxel in mouse carriers of mutation in BRIP1 tumor suppressor gene

Autor: E. Ntemou, P. Diaz Vidal, C. Alexandri, G. Van den Steen, M. Lambertini, I. Demeestere

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract More than 10% of women diagnosed with breast cancer during reproductive age carry hereditary germline pathogenic variants in high-penetrance BRCA genes or in others genes involved in DNA repair mechanisms such as PALB2, BRIP or ATM. Anticanc

Externí odkaz: https://doaj.org/article/22959b2e1a85485d80796d6104edc4b0

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Akademický článek

Impact of cancer on cryopreserved sperm quality and fertility: A cohort study

Autor: David Pening, Marnie Constant, Manon Bruynbroeck, Anne Delbaere, I. Demeestere

Publikováno v: Health Science Reports, Vol 5, Iss 4, Pp n/a-n/a (2022)

Abstract Background Sperm quality at cancer diagnosis is often compromised by the disease and any given gonadotoxic treatment will further diminish fertility. Objectives Here, we aim to analyze the cryopreserved sperm quality according to the cancer

Externí odkaz: https://doaj.org/article/c168d8cde3da45ee8d37ddf9d0302cad

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P-470 Impact of patient characteristics at ovarian tissue cryopreservation on follicle activation and survival

Autor: M Devos, P. Diaz Vidal, E Anckaert, M.M Dolmans, I Demeestere

Publikováno v: Human Reproduction. 37

Study question Does first-line chemotherapy prior to ovarian tissue cryopreservation and diseases impact on the signaling pathways governing follicle activation and survival in pre-pubertal and adult patients? Summary answer Chemotherapy increases fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fb5204eff2364be27d7ac2265671ea0
https://doi.org/10.1093/humrep/deac107.442

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P-455 Laparoscopic robot-assisted autologous transplantation of cryopreserved ovarian tissue: report of an operative technique and reproductive outcomes in a case series

Autor: M Fastrez, P Simon, J Dechene, E Van Den Abbeel, A Delbaere, I Demeestere

Publikováno v: Human Reproduction. 37

Study question Is laparoscopic robot-assisted autologous transplantation of ovarian tissue feasible and is the reproductive outcome adequate in comparison with published data? Summary answer Laparoscopic robot-assisted autologous transplantation of o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1c2d19d300c0c4dff9326602fec738e
https://doi.org/10.1093/humrep/deac107.428

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P-471 Effect of verteporfin, an inhibitor of Hippo signaling pathway, on chemotherapy-induced follicle activation and survival of neonatal mice ovaries in vitro

Autor: J Dias Nunes, M Devos, I Demeestere

Publikováno v: Human Reproduction. 37

Study question Does verteporfin, an inhibitor of Hippo signaling pathway, influence mechanisms involved in chemotherapy-induced follicle activation and survival in vitro? Summary answer Verteporfin acts directly on cell growth and indirectly on phosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d06c636bf923ca6cb36edb3cdfb9fd81
https://doi.org/10.1093/humrep/deac107.443

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Akademický článek

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Safety of fertility preservation techniques before and after anticancer treatments in young women with breast cancer: a systematic review and meta-analysis

Autor: L Arecco, E Blondeaux, M Bruzzone, M Ceppi, M M Latocca, C Marrocco, A Boutros, F Spagnolo, M G Razeti, D Favero, S Spinaci, M Condorelli, C Massarotti, O Goldrat, L Del Mastro, I Demeestere, M Lambertini

STUDY QUESTION Is it safe to perform controlled ovarian stimulation (COS) for fertility preservation before starting anticancer therapies or ART after treatments in young breast cancer patients? SUMMARY ANSWER Performing COS before, or ART following

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a1c21b1a79dfd874054c957749314e
http://hdl.handle.net/11567/1074526

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P–434 Effect of let–7a mimic as a new pharmaco-protective agent against chemotherapy-induced ovarian damage on subsequent follicular development and oocyte quality using mouse ovarian transplantation model

Autor: G Va. De. Steen, A Nguyen, I Demeestere, C Alexandri

Publikováno v: Human Reproduction. 36

Study question What is the long-term impact of let–7a-mimic transfection on oocytes development in new-born mice ovaries exposed to chemotherapy in vitro following transplantation in the kidney? Summary answer The let–7a-mimic restoration protect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f46328883d64eb00e350899d144a336
https://doi.org/10.1093/humrep/deab130.433

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