Zobrazeno 1 - 10
of 18
pro vyhledávání: '"I D, Horak"'
Autor:
I. D. Horak, Wm. Kevin Kelly, Morton K. Schwartz, Howard I. Scher, Weiping Wang, Zuo-Feng Zhang, A. B. Kremer, Min Sun, P. Ouyang, C. Ding
Publikováno v:
JNCI Journal of the National Cancer Institute. 91:244-251
Background: With an hypothesis that post-chemotherapy changes in serum prostate-specific antigen (PSA) levels might serve as a surrogate marker for assessing prostate cancer outcome (i.e., survival), we studied the relationship between pretherapy and
Publikováno v:
Neoplasma. 46(6)
G0 cells in a tumor are insensitive to the chemotherapeutical agents. The nature of this resistance is not completely understood. One of the factors modulating sensitivity of cells may be DNA repair of drug induced DNA damage. In this study we have c
Autor:
S J, Knox, M L, Goris, M, Tempero, P L, Weiden, L, Gentner, H, Breitz, G P, Adams, D, Axworthy, S, Gaffigan, K, Bryan, D R, Fisher, D, Colcher, I D, Horak, L M, Weiner
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(2)
A Phase II study of yttrium-90-tetra-azacyclododecanetetra-acetic acid-biotin (90Y-DOTA-biotin) pretargeted by NR-LU-10 antibody/streptavidin (SA) was performed. The primary objectives of the study were to evaluate the efficacy and safety of this the
Autor:
M, Adde, A, Shad, D, Venzon, C, Arndt, J, Gootenberg, J, Neely, M, Nieder, W, Owen, N, Seibel, W, Wilson, I D, Horak, I, Magrath
Publikováno v:
Seminars in oncology. 25(2 Suppl 4)
We report the updated results of an intensive treatment protocol for children (18 years) and adults (or = 18 years) with advanced B-cell lymphomas. The protocol consists of two chemotherapy regimens: A, consisting of cyclophosphamide, doxorubicin, vi
Autor:
F, Hartmann, E M, Horak, C, Cho, R, Lupu, J B, Bolen, M A, Stetler-Stevenson, M, Pfreundschuh, T A, Waldmann, I D, Horak
Publikováno v:
International journal of cancer. 70(2)
Geldanamycin belongs to the family of benzoquinoid ansamycin tyrosine-kinase inhibitors. We have examined its effects on Her-2/neu kinase activity, protein expression level, and proliferation of Her-2+ malignant cells. In SK-BR-3 breast-cancer cells,
Publikováno v:
Bailliere's clinical haematology. 9(4)
The NHLs are a group of neoplasms that share a common target tissue, and are characterized by a high degree of biological and clinical heterogeneity. Adult lymphomas with a high propensity for CNS involvement comprise SNCC, lymphoma (ATLL), LL, and P
Autor:
C Arndt, Melissa Adde, J. Neely, David Venzon, J Gootenberg, R. A. Wittes, Ian Magrath, I D Horak, Elaine S. Jaffe, M. Nieder, Aziza T. Shad, Nita L. Seibel
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 14(3)
PURPOSE We have used identical treatment protocols for adults and children with small non-cleaved-cell lymphoma (SNCL) for many years and report here the results of two successive treatment regimens in these age groups. PATIENTS AND METHODS Seventy-t
Autor:
I D Horak, Ian T. Magrath, M. Nieder, Nita L. Seibel, Melissa Adde, J Gootenberg, David Venzon, J. Neely, C Arndt, Michael Weintraub, Aziza T. Shad
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 14(3)
PURPOSE We have observed a severe atypical neuropathy (SAN) in patients with small non-cleaved-cell (SNCL) and large-cell lymphoma (LCL) treated with intensive chemotherapy and hematopoietic colony-stimulating factors (CSFs). The present analysis was
Publikováno v:
The Journal of biological chemistry. 268(28)
Bacterial lipopolysaccharide (LPS) induces a pleiotropic activation of the immune system which might subsequently result in septic shock. One of the cell surface receptors for LPS is the glycophosphatidylinositol-anchored protein CD14. Binding of LPS
Autor:
T A, Waldmann, J D, White, C K, Goldman, L, Top, A, Grant, R, Bamford, E, Roessler, I D, Horak, S, Zaknoen, C, Kasten-Sportes
Publikováno v:
Blood. 82(6)
Adult T-cell leukemia (ATL) is a malignancy of mature lymphocytes caused by the retrovirus human T-cell lymphotrophic virus-I (HTLV-I). It is an aggressive leukemia with an overall mortality rate of 50% within 5 months; no conventional chemotherapy r