Zobrazeno 1 - 10
of 107
pro vyhledávání: '"I D, Goldfine"'
Publikováno v:
Journal of Endocrinological Investigation. 20:531-536
Insulin receptor (IR) content is increased in most human breast carcinomas when compared to normal breast tissue. In the present study we investigated IR gene copy number by using both conventional DNA analysis (slot blot) and fluorescence in situ hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0b235bf5463276093107eb806885f5
https://doi.org/10.1007/bf03348015
https://doi.org/10.1007/bf03348015
Autor:
Riccardo Vigneri, Jack F. Youngren, Monica D’Adamo, P. Sbraccia, A. Buongiorno, I. D. Goldfine, Lucia Frittitta, Vincenzo Trischitta
Publikováno v:
Diabetologia. 40:282-289
In the present study we measured PC-1 content, tumour necrosis factor (TNF)-α gene expression, and insulin stimulation of insulin receptor tyrosine-kinase activity in adipose tissue from non-obese, non-diabetic subjects. These parameters were correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1b690f79bd6a71ff4362e2d9c8fd95
https://doi.org/10.1007/s001250050675
https://doi.org/10.1007/s001250050675
Autor:
I. D. Goldfine, Antonio Brunetti
Publikováno v:
Journal of Endocrinological Investigation. 18:398-405
Non-insulin-dependent diabetes mellitus (NIDDM) is one of the more common endocrine diseases, affecting about 5-7% of the population (1, 2). Its prevalence rate is even higher in certain populations such as Hispanic-Americans, and Native Americans (3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ccf2dd5dbf2dcb8c852bef0f7e20472
https://doi.org/10.1007/bf03347847
https://doi.org/10.1007/bf03347847
Autor:
P. Russo, Biancamaria Gliozzo, Vincenzo Papa, Riccardo Vigneri, I. D. Goldfine, Vincenzo Pezzino
Publikováno v:
Endocrinology. 133:1369-1376
We have recently reported that the insulin receptor (IR), a tetrameric transmembrane protein located on the surface of target cells, is present as a soluble form in human plasma. In the present study we investigated whether human cells in culture rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134755288c49305dc9c89a2a98e5b845
https://doi.org/10.1210/endo.133.3.8396017
https://doi.org/10.1210/endo.133.3.8396017
Autor:
Clarie B Hollenbeck, R. Skowronski, P. Johnston, Gerald M. Reaven, I D Goldfine, J C Zhang, Yi Chen
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 74:1020-1026
The effect of metformin treatment was studied in 13 patients with noninsulin-dependent diabetes mellitus (NIDDM), whose fasting plasma glucose concentration was greater than 10 mmol/L with maximal sulfonylurea doses. Patients were studied before and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bad21db2a58e3bf0fe89724e9976a3
https://doi.org/10.1210/jcem.74.5.1569149
https://doi.org/10.1210/jcem.74.5.1569149
Autor:
Lucia Frittitta, Riccardo Vigneri, A. Costantino, I. D. Goldfine, Vincenzo Papa, Vincenzo Pezzino, P. Russo
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 74:1116-1121
With a two-step purification procedure employing sequential affinity chromatography with insulin receptor monoclonal antibody followed by wheat germ agglutinin, we isolated from the plasma of two healthy individuals a material that reacted in a speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6f16482e2db81cfdd8c3fd2598e0fa
https://doi.org/10.1210/jcem.74.5.1314845
https://doi.org/10.1210/jcem.74.5.1314845
Autor:
P. Sbraccia, P. A. Goodman, B. A. Maddux, K. Y. Wong, Y. D. Chen, G. M. Reaven, I. D. Goldfine
Publikováno v:
Diabetes. 40:295-299
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86e310e196b9b0c704eebb646529928a
https://doi.org/10.2337/diabetes.40.2.295
https://doi.org/10.2337/diabetes.40.2.295
Autor:
I D Goldfine, Betty A. Maddux
Publikováno v:
Diabetes. 49(1)
Plasma cell membrane glycoprotein-1 (PC-1) inhibits insulin receptor (IR) tyrosine kinase activity and subsequent cellular signaling. PC-1 content is elevated in fibroblasts, muscle, and adipose tissue from insulin-resistant subjects, and its elevati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91170dc3027d921bfe12987cf634454f
https://pubmed.ncbi.nlm.nih.gov/10615944
https://pubmed.ncbi.nlm.nih.gov/10615944
Autor:
G, Pandini, R, Vigneri, A, Costantino, F, Frasca, A, Ippolito, Y, Fujita-Yamaguchi, K, Siddle, I D, Goldfine, A, Belfiore
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(7)
The insulin receptor (IR) form hybrids with the closely related insulin-like growth factor-I (IGF-I) receptor (IGF-I-R). Because most human breast carcinomas overexpress both the IR and the IGF-I-R, we evaluated whether the insulin/IGF-I hybrid recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6817026328532b9f752584fa403809ac
https://pubmed.ncbi.nlm.nih.gov/10430101
https://pubmed.ncbi.nlm.nih.gov/10430101
Publikováno v:
Molecular and cellular biochemistry. 182(1-2)
Peripheral resistance to insulin is a major component of non-insulin dependent diabetes mellitus. Defects in insulin receptor tyrosine kinase activity have been demonstrated in several tissues from insulin resistant subjects, but mutations in the ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::311d56037a78eee80cf633d3cac589f2
https://pubmed.ncbi.nlm.nih.gov/9609127
https://pubmed.ncbi.nlm.nih.gov/9609127