Zobrazeno 1 - 10
of 32
pro vyhledávání: '"I C, McMillen"'
Autor:
K J, Botting, K C W, Wang, M, Padhee, I C, McMillen, B, Summers-Pearce, L, Rattanatray, N, Cutri, G S, Posterino, D A, Brooks, J L, Morrison
Publikováno v:
Clinical and experimental pharmacologyphysiology. 39(9)
1. World-wide epidemiological and experimental animal studies demonstrate that adversity in fetal life, resulting in intrauterine growth restriction, programmes the offspring for a greater susceptibility to ischaemic heart disease and heart failure i
Autor:
B S, Muhlhausler, J A, Duffield, S E, Ozanne, C, Pilgrim, N, Turner, J L, Morrison, I C, McMillen
Publikováno v:
The Journal of physiology. 587(Pt 17)
A world-wide series of epidemiological and experimental studies have demonstrated that there is an association between being small at birth, accelerated growth in early postnatal life and the emergence of insulin resistance in adult life. The aim of
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(8)
Individuals exposed to an increased nutrient supply before birth have a high risk of becoming obese children and adults. It has been proposed that exposure of the fetus to high maternal nutrient intake results in permanent changes within the central
Publikováno v:
The Journal of physiology. 565(Pt 1)
Recent studies in the sheep have shown that maternal undernutrition during the periconceptional period, when the nutrient demands of the embryo are minimal, can alter the subsequent development of the metabolic, endocrine and cardiovascular systems a
Publikováno v:
Biology of reproduction. 71(2)
It is not clear if an increase in intra-adrenal cortisol is required to mediate the actions of adrenocorticotropic hormone (ACTH) on adrenal growth and steroidogenesis during the prepartum stimulation of the fetal pituitary-adrenal axis. We infused m
Autor:
B S J, Yuen, P C, Owens, M E, Symonds, D H, Keisler, J R, McFarlane, K G, Kauter, I C, McMillen
Publikováno v:
Biology of reproduction. 70(6)
We investigated whether leptin can suppress the prepartum activation of the fetal hypothalamus-pituitary-adrenal (HPA) axis and delay the timing of parturition in the sheep. First, we investigated the effects of a 4-day intravascular infusion of reco
While the impact of exogenous glucocorticoids on the fetal cardiovascular system has been well defined, relatively few studies have characterised the role of endogenous fetal glucocorticoids in the regulation of arterial blood pressure (BP) during la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64b71c37137f744dc8b7ecf4583b932
https://hdl.handle.net/1959.8/87472
https://hdl.handle.net/1959.8/87472
Publikováno v:
Biology of reproduction. 67(2)
In adults, circulating leptin concentrations are dependent on body fat content and on current nutritional status. However, the relationships among maternal nutrient intake, fetal adiposity, and circulating leptin concentrations before birth are unkno
Publikováno v:
Biochemical Society transactions. 29(Pt 2)
The elucidation of the tissue-specific profile of expression of the prolactin (PRL) and growth hormone (GH) receptors during embryonic and fetal development in a range of species has provided a new impetus for the delineation of the specific roles of
Autor:
L J, Edwards, M E, Symonds, K E, Warnes, J A, Owens, T G, Butler, A, Jurisevic, I C, McMillen
Publikováno v:
Endocrinology. 142(5)
We investigated the response of the fetal pituitary-adrenal axis to acute and chronic hypoglycemia before and after the normal prepartum activation of this axis at around 135 days gestation (term = 147 +/- 3 days). Pregnant ewes were either well nour