Zobrazeno 1 - 10
of 77
pro vyhledávání: '"I Brotherick"'
Autor:
D.A. BroweIl, Adrian Allen, JM Hanson, I Brotherick, J.R. Young, D Hemming, WJ Cunliffe, Jeffrey P. Pearson, MJ Higgs, Brian K. Shenton, J. S. Varma
Publikováno v:
Breast Cancer Research and Treatment. 67:215-222
This was a non-randomised single institution retrospective study. Forty-six banked frozen tumour specimens were obtained from a group of patients who had undergone 3 weeks of neoadjuvant treatment with tamoxifen between biopsy and surgery. Fifty-one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d397176311c61fe3504c557ea9e713b2
https://doi.org/10.1023/a:1017955726902
https://doi.org/10.1023/a:1017955726902
Autor:
Neil James Gibson, David Mark Whitcombe, Jayne C. Fox, Darren Hodgson, Peter Ceuppens, Simon J. Clayton, F Girdler, I Brotherick, David Browell, Carole A. Foy, Brian K. Shenton, Mary Stuart
Publikováno v:
Clinical Chemistry. 47:774-778
Alterations in the p53 gene have been reported in approximately one-half of human tumors (1). Much debate surrounds the clinical significance of p53 mutations as measured directly or inferred by immunohistochemical staining (2). Many studies have add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0169376e7054e5cc4501fb205fb6371
https://doi.org/10.1093/clinchem/47.4.774
https://doi.org/10.1093/clinchem/47.4.774
Autor:
I Brotherick, J. D. Hemming, Brian K. Shenton, J.R. Young, P. Scorer, F Girdler, D. A. Browell, WJ Cunliffe
Publikováno v:
Cytometry. 45:65-72
Background Oestrogen receptor beta (ERβ) is highly homologous with the classical ER (known now as ERα). The exact role of ERβ in breast cancer and its contribution in influencing patient response to endocrine therapy remains unclear. The aim of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43203723dccb5247aad11a730d0a7d58
https://doi.org/10.1002/1097-0320(20010901)45:1<65::aid-cyto1145>3.0.co
https://doi.org/10.1002/1097-0320(20010901)45:1<65::aid-cyto1145>3.0.co
Autor:
I. Brotherick, F. Girdler
Publikováno v:
The Breast. 9:194-200
One of the main prognostic markers measured in breast tumours is oestrogen receptor (ER) status. With the discovery of ER beta, it has been necessary to re-evaluate ER signalling and the role of ER in breast cancer. Preliminary reports on ER beta sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b79ac8ff6a3c04877493c9ab01fc937
https://doi.org/10.1054/brst.2000.0203
https://doi.org/10.1054/brst.2000.0203
Publikováno v:
Clinical Chemistry. 45:292-295
The search for diagnostic and prognostic factors in breast cancer has included several oncogenes, particularly c- erb -B2, which encodes a 185-kDa transmembrane glycoprotein receptor, denoted p185, with tyrosine kinase activity (1)(2). p185 is freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb06fb0980dd7902935a38672bd93bab
https://doi.org/10.1093/clinchem/45.2.292
https://doi.org/10.1093/clinchem/45.2.292
Publikováno v:
British Journal of Cancer
Increased expression of oestrogen (ER) and progesterone (PR) receptors have been reported in gastric adenocarcinoma, although results have been variable. Immunohistochemical staining methodologies, in particular in the detection of ER, have been inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6726c4cf0b35668378e5889b83e758e3
http://europepmc.org/articles/PMC2362374
http://europepmc.org/articles/PMC2362374
Autor:
J. Shenfine, L.A. Webb, D. A. Browell, Mark White, L.G. Lunt, W.J. Cunliffe, Brian K. Shenton, C.N. Robson, I Brotherick, J.R. Young, MJ Higgs, M. Egan
Publikováno v:
Cytometry. 32:301-308
Transition from a normal to a cancerous state is marked by alterations in the cytoskeletal structure of those cells involved. We have examined such changes to determine if these transitions are markers of disease progression. Cytokeratin (CK) protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::201d427855abbacfb6171d47270e422f
https://doi.org/10.1002/(sici)1097-0320(19980801)32:4<301::aid-cyto7>3.0.co
https://doi.org/10.1002/(sici)1097-0320(19980801)32:4<301::aid-cyto7>3.0.co
Autor:
L.G. Lunt, D.A. Browell, MJ Higgs, I Brotherick, J.R. Young, B.K. Shenton, M. Egan, W.E. Cunliffe
Publikováno v:
European Journal of Cancer. 32:2334-2341
The aim of this study was to measure multidrug resistance (MDR) by flow cytometry and quantify the expression of P-glycoprotein (using antibody) glutathione transferase (using alpha-GSTpi antibody) in alpha-JSB-1 and alpha-GSTpi of a series of cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1d004a68accab1d390f716f7e0b6c0
https://doi.org/10.1016/s0959-8049(96)00344-9
https://doi.org/10.1016/s0959-8049(96)00344-9
Autor:
I Brotherick, B.K. Shenton, Chw Horne, White, DM McKenna, J K Mellon, R. I. Bishop, T. R. L. Griffiths, David E. Neal
Publikováno v:
British Journal of Cancer
Scopus-Elsevier
Scopus-Elsevier
Sera from 40 patients with newly diagnosed bladder cancer (28 superficial tumours (pTa and pT1) and 12 muscle-invasive tumours) were assessed by enzyme-linked immunosorbent assay (ELISA) to determine the concentrations of soluble E-cadherin (sE-cadhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2533b1aa12f0358df12c36b4d5cde61
http://europepmc.org/articles/PMC2074678
http://europepmc.org/articles/PMC2074678
Publikováno v:
British Journal of Cancer
Fifty-three solid and 33 fine-needle aspirate (FNA) samples (20 paired) of human breast carcinomas were examined by flow cytometry. Experiments were conducted to assess whether FNA samples were phenotypically representative of the solid tumour. Quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93800ab3345d039128c76255ebd65a07
https://doi.org/10.1038/bjc.1995.402
https://doi.org/10.1038/bjc.1995.402