Zobrazeno 1 - 10
of 414
pro vyhledávání: '"I Boime"'
Publikováno v:
Journal of Biological Chemistry. 269:10574-10580
There are six intramolecular disulfide (S-S) bonds that form during intracellular folding of the human chorionic gonadotropin (hCG)-beta subunit. Site-directed mutagenesis of every pair of Cys residues involved in the formation of each S-S bond was u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10df0a25403b98a92c88cc4bac8cc99e
https://doi.org/10.1016/s0021-9258(17)34098-x
https://doi.org/10.1016/s0021-9258(17)34098-x
Publikováno v:
Endocrinology. 141(12)
The crystal structure of human CG reveals that each subunit is a member of the superfamily of cystine-knot growth factors. Although the distribution of the cysteine residues in all the beta-subunits is conserved, the conformation of the human FSH dim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bacc693aa4b148e495cf4fa2adf3091
https://pubmed.ncbi.nlm.nih.gov/11108290
https://pubmed.ncbi.nlm.nih.gov/11108290
Publikováno v:
European journal of immunology. 28(11)
During mammalian pregnancy, one or more semiallogeneic fetuses gestate in direct contact with the maternal circulation and uterine tissue. However, a damaging maternal immune response is not normally provoked. We studied two possible mechanisms for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f799f39bcc99d1cc7e7fa6651146000c
https://pubmed.ncbi.nlm.nih.gov/9842890
https://pubmed.ncbi.nlm.nih.gov/9842890
Autor:
T, Moriwaki, N, Suganuma, M, Furuhashi, F, Kikkawa, Y, Tomoda, I, Boime, M, Nakata, T, Mizuochi
Publikováno v:
Glycoconjugate journal. 14(2)
The human chorionic gonadotropin beta-subunit (hCGbeta) is a glycoprotein in which 12 cysteine residues pair to form six intramolecular disulfide bonds. In order to elucidate the effect of each disulfide bond on glycosylation of the molecule, we anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb3d17e2387c4a59e2fb3d5da97a3049
https://pubmed.ncbi.nlm.nih.gov/9111139
https://pubmed.ncbi.nlm.nih.gov/9111139
Publikováno v:
The Journal of biological chemistry. 271(18)
The gonadotropin/thyrotropin hormone family is characterized by a heterodimeric structure composed of a common alpha subunit noncovalently linked to a hormone-specific beta subunit. The conformation of the heterodimer is essential for controlling sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::390d127b2d062d8aadc001572bde3fd2
https://pubmed.ncbi.nlm.nih.gov/8631838
https://pubmed.ncbi.nlm.nih.gov/8631838
Autor:
D, Ben-Menahem, I, Boime
Publikováno v:
Trends in endocrinology and metabolism: TEM. 7(3)
One of the distinguishing features of the gonadotropin and thyrotropin hormone family is their heterodimeric structure; the subunits combine early in the secretory pathway and only the dimers are capable of binding to receptors. Therefore, assembly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54a5a102de25fabed4ddd003e340d928
https://pubmed.ncbi.nlm.nih.gov/18406733
https://pubmed.ncbi.nlm.nih.gov/18406733
Publikováno v:
The Journal of biological chemistry. 269(41)
Human chorionic gonadotropin (hCG) is a member of a family of heterodimeric glycoprotein hormones that contain a common alpha subunit but differ in their hormone-specific beta subunits. Site-directed mutagenesis was used to examine the role of the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::925a70bed2c5a5ccf1a7516f3e410649
https://pubmed.ncbi.nlm.nih.gov/7929256
https://pubmed.ncbi.nlm.nih.gov/7929256
Publikováno v:
The Journal of biological chemistry. 269(14)
There are six intramolecular disulfide (S-S) bonds that form during intracellular folding of the human chorionic gonadotropin (hCG)-beta subunit. Site-directed mutagenesis of every pair of Cys residues involved in the formation of each S-S bond was u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b81290646c523cc0e3f4f1dd66f8fb7a
https://pubmed.ncbi.nlm.nih.gov/8144645
https://pubmed.ncbi.nlm.nih.gov/8144645
Publikováno v:
The Journal of biological chemistry. 269(7)
Transcriptional activation of the chorionic gonadotropin (CG) genes is linked to trophoblast differentiation. In a multistep process, cytotrophoblasts expressing only the alpha subunit differentiate into intermediates that coexpress the CG beta subun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e76c88dd0a9ff46c702e410fefedc8b
https://pubmed.ncbi.nlm.nih.gov/7508931
https://pubmed.ncbi.nlm.nih.gov/7508931