Zobrazeno 1 - 10
of 290
pro vyhledávání: '"I Bernard, Weinstein"'
Autor:
Andrew K. Joe, I. Bernard Weinstein
Publikováno v:
Encyclopedia of Cancer ISBN: 9783642278419
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8ffaeb9a31732e2194fca801720e30
https://doi.org/10.1007/978-3-662-46875-3_4222
https://doi.org/10.1007/978-3-662-46875-3_4222
Autor:
Haiyang Li, Yu-Jing Zhang, Regina M. Santella, Ming-Whei Yu, Lin Wang, I. Bernard Weinstein, Hui-Chen Wu, Po-Huang Lee, Jing Shen
Publikováno v:
Cancer Letters. 275:277-284
The Hint1 protein, a member of the histidine triad (HIT) family, is highly conserved in diverse species and ubiquitously expressed in mammalian tissues. Previous studies in mice provided evidence that Hint1 may be haploinsufficient with respect to it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085c037d6672b7122fc55fc0f50deac2
https://doi.org/10.1016/j.canlet.2008.10.042
https://doi.org/10.1016/j.canlet.2008.10.042
Publikováno v:
The Journal of Cell Biology
Hint1 is a haploinsufficient tumor suppressor gene and the underlying molecular mechanisms for its tumor suppressor function are unknown. In this study we demonstrate that HINT1 participates in ionizing radiation (IR)-induced DNA damage responses. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9a062f7c77b04c2cc33dd292cbca2d
https://doi.org/10.1083/jcb.200711150
https://doi.org/10.1083/jcb.200711150
Publikováno v:
Cancer Research. 68:5355-5362
The anticancer role of cyclic guanosine 3′,5′-monophosphate (cGMP)–dependent protein kinase G (PKG) has become of considerable interest, but the underlying mechanisms are not fully established. In this study, we examined the effects of activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78695a6dd2576893049b4e5235f8b29e
https://doi.org/10.1158/0008-5472.can-07-6869
https://doi.org/10.1158/0008-5472.can-07-6869
Autor:
I Bernard, Weinstein, Andrew, Joe
Publikováno v:
Cancer Research. 68:3077-3080
Cancer cells contain multiple genetic and epigenetic abnormalities. Despite this complexity, their growth and survival can often be impaired by the inactivation of a single oncogene. This phenomenon, called “oncogene addiction,” provides a ration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1e86df27008f6e2a956188ded7f4fc
https://doi.org/10.1158/0008-5472.can-07-3293
https://doi.org/10.1158/0008-5472.can-07-3293
Autor:
Masahito Shimizu, Hiroyasu Sakai, Takayuki Nakagawa, Yohei Shirakami, Hideharu Tatebe, Hisataka Moriwaki, I. Bernard Weinstein, Yukihiko Hara
Publikováno v:
Cancer Letters. 262:10-18
The receptor tyrosine kinase (RTK) insulin like growth factor-1 (IGF-1)/IGF-1 receptor (IGF-1R) axis plays an important role in the development of hepatocellular carcinoma (HCC). EGCG inhibits activation of the various types of RTKs and that this is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b18b7cc634f15ed0d5269fa339f0479
https://doi.org/10.1016/j.canlet.2007.11.026
https://doi.org/10.1016/j.canlet.2007.11.026
Autor:
Andrew K. Joe, Rie Matsushima-Nishiwaki, Satoshi To, Masahito Shimizu, I. Bernard Weinstein, Tomokazu Nagao, Frederick R. Maxfield, Hisataka Moriwaki, Osamu Kozawa, Seiji Adachi
Publikováno v:
Carcinogenesis. 29:1986-1993
We recently found that the inhibitory effect of (-)-epigallocatechin gallate (EGCG) on epidermal growth factor (EGF) binding to the epidermal growth factor receptor (EGFR) is associated with alterations in lipid organization in the plasma membrane of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b9961a829edba0122dba01fea8caab
https://doi.org/10.1093/carcin/bgn128
https://doi.org/10.1093/carcin/bgn128
Autor:
Hui Yang, Roberto R. Gil, Edward J. Kennelly, I. Bernard Weinstein, Kurt A. Reynertson, Mario J. Simirgiotis, Margaret J. Basile, Seiji Adachi, Satoshi To
Publikováno v:
Food Chemistry. 107:813-819
Bioassay-guided fractionation of the methanolic extracts of the pulp and seeds of the fruits of Syzygium samarangense (Blume) Merr. and L.M. Perry led to the identification of four cytotoxic compounds and eight antioxidants on the basis of HPLC-PDA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3769a9597e4b06cb70ee0da2f71fe9c0
https://doi.org/10.1016/j.foodchem.2007.08.086
https://doi.org/10.1016/j.foodchem.2007.08.086
Autor:
I. Bernard Weinstein, Iryna Voloshyna, Mireia Castillo, Richard B. Robinson, Alessandra Besana, Steven J. Feinmark, Tulio Matos, Carlos Cordon-Cardo, Mahesh Mansukhani
Publikováno v:
Cancer Research. 68:1197-1203
TREK-1 is a two-pore domain (K2P) potassium channel that carries a leak current that is time- and voltage-independent. Recently, potassium channels have been related to cell proliferation and some K2P family channels, such as TASK-3, have been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac08caaf8817ec10d2aa4674ae1674d
https://doi.org/10.1158/0008-5472.can-07-5163
https://doi.org/10.1158/0008-5472.can-07-5163
Autor:
Shizuo Komune, Muneyuki Masuda, Satoshi Toh, I. Bernard Weinstein, Yuichiro Kutratomi, Torahiko Nakashima, Ryuji Yasumatsu, Aya Ito, Hong Ying Ruan, Takahiro Wakasaki
Publikováno v:
Oral Oncology. 43:785-790
Overexpression of vascular endothelial growth factor (VEGF) is associated with angiogenic phenotypes and poor prognosis of numerous tumors, including head and neck squamous cell carcinoma (HNSCC). However, the precise mechanism that causes VEGF overe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81685121feb9b03e7be62e9c4bc9467b
https://doi.org/10.1016/j.oraloncology.2006.10.007
https://doi.org/10.1016/j.oraloncology.2006.10.007