Zobrazeno 1 - 10
of 137
pro vyhledávání: '"I Bartosek"'
Publikováno v:
British Journal of Cancer
Cis-platinum (CDDP) induces severe inhibition of cell activation and cell cycle progression in PHA-stimulated human PBL's. Applying the novel BrdU/Hoechst flow cytometric technique for high resolution cell cycle analysis we show that CDDP induced mul
Autor:
R, Gandini, C, Montalto, D, Castoldi, V, Monzani, M L, Nava, I, Scaricabarozzi, G, Vargiu, I, Bartosek
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 46(9)
The pharmacokinetics of nimesulide (4-nitro-2-phenoxymethane-sulfonanilide, NMS), a non-steroidal antiinflammatory drug, and of its 4-hydroxy metabolite (4-nitro-2-(4'-hydroxy-phenoxy)-methane sulfonanilide, OH-NMS) was studied after a single oral do
Publikováno v:
Cancer chemotherapy and pharmacology. 28(4)
The plasma and tissue pharmacokinetics of fotemustine (diethyl-1-[3-(2-chlorethyl)-3-nitrosoureido]-ethylphosphonate+ ++) and BCNU (1,3-bis-[2-chlorethyl]-1-nitrosourea) were investigated in healthy control rats and in animals bearing either the nitr
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 665:331-338
Nephrotic syndrome induced in the rat by the administration of puromycin aminonucleoside is accompanied by a hyperlipoproteinemia characterized by an elevation of all plasma lipoproteins, particularly of VLDL (1.006 g/ml) and HDL 1 (1.050–1.090 g/m
Publikováno v:
Experimental Gerontology. 24:159-171
Doxorubicin (Dx) toxicity was compared in old (24 months) and young (6 weeks) Crl:CD(SD) BR male rats, and a clear age-related increase was found. The mortality of all animals receiving a single i.v. Dx dose was followed for 270 days. Old rats died a
Publikováno v:
Pharmacology. 13(3)
Perfused livers obtained from rats fasted for 24 or 48h show a marked impairment of the N-demethylation (substrate aminopyrine) without major changes of the O-demethylation (p-nitro anisol) and hydroxylation (aniline). The infusion with nicotinic aci
Differential pulse polarographic determination of BCNU pharmacokinetics in patients with lung cancer
Publikováno v:
Cancer treatment reports. 65(7-8)
BCNU levels were determined by differential pulse polarography in 12 patients with lung cancer. A simple assay method for submicrogram quantities of nitrosoureas is described. The half-life of BCNU added to plasma in vitro was 1413 mins at 0 degrees
Publikováno v:
Complications of Cancer Chemotherapy ISBN: 9783642808500
The presence of a tumor in a host results in marked changes at the levels of various organs, including the liver. A functional change in the liver metabolism maybe detected by measuring the activity and the metabolism of drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cb947b06c80d99f8a5a219f15231a0a
https://doi.org/10.1007/978-3-642-80848-7_15
https://doi.org/10.1007/978-3-642-80848-7_15
Publikováno v:
Cancer research. 45(5)
Line A Walker carcinoma differs from line B in that it does not elicit hypercalcemia and hypercalciuria when implanted in rats at various sites (s.c, i.m., intraaortically). However, Walker 256/A, unlike line B, may invade the tibia when implanted i.
Publikováno v:
Acta biologica et medica Germanica. 8