Zobrazeno 1 - 10
of 295
pro vyhledávání: '"I B Weinstein"'
Autor:
I. B. Weinstein, D. Grunberger
Publikováno v:
Chemical Carcinogens and DNA ISBN: 9780429260698
This chapter reviews the conformational changes in nucleic acids associated with noncovalent binding and intercalation with certain drugs and carcinogens. Conformational changes associated with covalent modification by chemical carcinogens can be stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b6c68a5028832119e5efd38397af7a9
https://doi.org/10.1201/9780429260698-3
https://doi.org/10.1201/9780429260698-3
Autor:
David J. Zegarelli, Angela J. Yoon, Rongzhen Chen, Jing Shen, Regina M. Santella, I. B. Weinstein
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 16:2768-2772
Background: Phosphoactivation of a DNA damage response molecule checkpoint kinase 2 (pChk2) may be a marker of oral epithelial cells that have entered the precancerous and squamous cell carcinoma (SCC) stages. We explored whether there was selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02994c2bb7dc998862c73bd278e79f31
https://doi.org/10.1158/1055-9965.epi-07-0659
https://doi.org/10.1158/1055-9965.epi-07-0659
Publikováno v:
Oncogene. 18:6658-6666
To clarify the roles of specific isoforms of PKC in regulating growth and cell cycle progression of the HC11 mammary epithelial cell line, we investigated the effects of activating endogenous PKC isoforms with the phorbol ester tumor promoter TPA, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa2b31cfd123956dc64685403c0ca38
https://doi.org/10.1038/sj.onc.1203083
https://doi.org/10.1038/sj.onc.1203083
Autor:
Richard J. Deckelbaum, F. X. Pi-Sunyer, R. M. Lauer, Shiriki K. Kumanyika, Mary Winston, Ernst J. Schaefer, S. T. St. Jeor, Edward A. Fisher, I. B. Weinstein
Publikováno v:
Circulation. 100:450-456
The Nutrition Committee of the American Heart Association, with cooperation and support from the Council on Cardiovascular Disease in the Young and the Council on Epidemiology and Prevention, convened a scientific conference on “Preventive Nutritio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84e540e44cb58371ed9dccbb9c5581e6
https://doi.org/10.1161/01.cir.100.4.450
https://doi.org/10.1161/01.cir.100.4.450
Autor:
Jae-Won Soh, Eric D. Slosberg, Naruya Tomita, W.-Q. Xing, I. Schieren, Yao Yao, Haim Shirin, Hirofumi Yamamoto, I. B. Weinstein, J. T. E. Lim
Publikováno v:
Oncogene. 18:103-115
Recent studies have shown that decreased expression of p27Kip1 is associated with high grade tumors and an unfavorable prognosis in several types of human cancer. To clarify the role of p27Kip1 in colon cancer, we have overexpressed this protein in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d444d40e9b1fc5014acd64bbb9d9174
https://doi.org/10.1038/sj.onc.1202269
https://doi.org/10.1038/sj.onc.1202269
Publikováno v:
APOPTOSIS. 4:213-219
It is now apparent that apoptosis is closely linked to the control of cell cycle progression. During the G1 to S progression, cyclin D1, p53, and the cyclin dependent kinase inhibitors p21WAF1 and p27kip1 can play roles in induction of apoptosis. Dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ff3d3d31e510df415649132f3230408
https://doi.org/10.1023/a:1009618824145
https://doi.org/10.1023/a:1009618824145
Publikováno v:
Japanese Journal of Cancer Research : Gann
By using a retrovirus-derived system we generated derivatives of the human colon adenocarcinoma cell line LS174T (ATCC CL 188) that stably overexpress a full-length cDNA encoding the beta 1 isoform of bovine phosphoinositides-specific phospholipase C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97123ea8ad3987ae005f72423fabc503
https://doi.org/10.1111/j.1349-7006.1998.tb00522.x
https://doi.org/10.1111/j.1349-7006.1998.tb00522.x
Publikováno v:
The Prostate. 35:95-101
Background The cyclin D1 gene is amplified and/or overexpressed in several types of human cancer, including cancers of the breast, esophagus, head, and neck. However, the role of cyclin D1 in prostate cancer has not been previously studied in detail.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0d557872d2e918bf98e32158e35fc7c
https://doi.org/10.1002/(sici)1097-0045(19980501)35:2<95::aid-pros2>3.0.co
https://doi.org/10.1002/(sici)1097-0045(19980501)35:2<95::aid-pros2>3.0.co
Autor:
V. S. Venkatraj, Jeffrey N. Bruce, A. Sobrino, I. B. Weinstein, Dorothy Warburton, Martin Begemann
Publikováno v:
Journal of Neuro-Oncology. 36:141-148
Comparative genomic hybridization serves as a screening test for regions of copy number changes in tumor genomes. We have applied the technique to map DNA gains and losses in 5 cell lines derived from glioblastoma multiforme, the most common primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f117fa56ece4a262240b71bc42d9574
https://doi.org/10.1023/a:1005859318971
https://doi.org/10.1023/a:1005859318971
Autor:
Peter R. Holt, Christopher M. Weghorst, Thomas Delohery, N Arber, Dennis J. Ahnen, G. A. Piazza, N.-H. Kim, J. C. Reed, E. K.-H. Han, R. Pamukcu, Martin Begemann, Alessandro Sgambato, I. B. Weinstein
Publikováno v:
Gastroenterology. 113:1892-1900
BACKGROUND & AIMS: Mutations of c-K-ras occur commonly in colonic neoplasms. The aim of this study was to determine how c-K-ras mutations alter the responses to the chemopreventive agent sulindac. METHODS: The parental rat intestinal cell line IEC-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1825bb77694184b7526b4d4498e2ff6c
https://doi.org/10.1016/s0016-5085(97)70008-8
https://doi.org/10.1016/s0016-5085(97)70008-8