Zobrazeno 1 - 9
of 9
pro vyhledávání: '"I B, Bronstein"'
Autor:
Thomas R. Griffiths, Svetlana Tarabykina, I. B. Bronstein, Eugene Tulchinsky, J K Mellon, Marina Kriajevska
Publikováno v:
Current Cancer Drug Targets. 7:217-228
S100A4 (also known as Mts1, metastasin, p9Ka, pEL98, CAPL, calvasculin, Fsp-1, placental calcium-binding protein) belongs to the family of EF-hand calcium-binding proteins, whose expression is elevated in a number of pathological conditions. Although
Autor:
I. B. Bronstein, Einar K. Kristoffersen, T. Wentzel‐Larsen, M. K. Fagerhol, Annette Larsen, Olav Dahl
Publikováno v:
Scandinavian Journal of Immunology. 65:192-201
S100A12 is a calcium-binding protein predominantly found in neutrophil granulocytes and monocytes. Its usefulness in monitoring inflammatory disease states depends on documentation that assay results are reliable. This study aimed at defining guideli
Publikováno v:
Anticancer research. 21(2A)
New anticancer drugs targeting DNA topoisomerase I (topo I) are showing activity against gastric carcinomas. Laboratory studies have indicated that cells responsive to topo I targeted drugs have elevated levels of topo I, require active DNA replicati
Autor:
S, Tarabykina, D J, Scott, P, Herzyk, T J, Hill, J R, Tame, M, Kriajevska, D, Lafitte, P J, Derrick, G G, Dodson, N J, Maitland, E M, Lukanidin, I B, Bronstein
Publikováno v:
The Journal of biological chemistry. 276(26)
The S100 calcium-binding proteins are implicated in signal transduction, motility, and cytoskeletal dynamics. The three-dimensional structure of several S100 proteins revealed that the proteins form non-covalent dimers. However, the mechanism of the
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 12(4)
New anticancer drugs targeting DNA topoisomerase I (Topo I) are now approved for clinical use for the treatment of colon cancer. From laboratory work, it is known that tumors cells with high Topo I are sensitive to these drugs and that tumor cells wi
Autor:
I B, Bronstein, A, Wynne-Jones, A, Sukhanova, F, Fleury, A, Ianoul, J A, Holden, A J, Alix, G G, Dodson, J C, Jardillier, I, Nabiev, A J, Wilkinson
Publikováno v:
Anticancer research. 19(1A)
The gene encoding human DNA topoisomerase (topo) I, the target of numerous anticancer drugs, has been subcloned into bacterial, yeast and baculovirus-based expression systems in attempts to overexpress the enzyme for extensive structural and function
Publikováno v:
Oncology research. 8(1)
DNA topoisomerase I (topo I) is the molecular target for the camptothecin group of anticancer drugs. These drugs are showing activity against a wide array of human tumors. Many data have indicated that the sensitivity of a tumor cell to the camptothe
Publikováno v:
Biopolymers and Cell. 1:32-40
Publikováno v:
Europe PubMed Central