Zobrazeno 1 - 10
of 676
pro vyhledávání: '"I Abrams"'
Autor:
Angela R. Omilian, Rikki Cannioto, Lucas Mendicino, Leighton Stein, Wiam Bshara, Bo Qin, Elisa V. Bandera, Nur Zeinomar, Scott I. Abrams, Chi-Chen Hong, Song Yao, Thaer Khoury, Christine B. Ambrosone
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-12 (2024)
Abstract Background Tumor-associated macrophages (TAMs) are a prominent immune subpopulation in the tumor microenvironment that could potentially serve as therapeutic targets for breast cancer. Thus, it is important to characterize this cell populati
Externí odkaz:
https://doaj.org/article/6f527a7fa43b4abe837920ef9add5330
Autor:
Jeffrey C. Martin, Tatiane da Silva Fernandes, Kanita A. Chaudhry, Masanori Oshi, Scott I. Abrams, Kazuaki Takabe, Spencer R. Rosario, Anna Bianchi-Smiraglia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Triple-negative breast cancer (TNBC) is one of the most aggressive types of cancer. Despite decades of intense investigation, treatment options remain limited, and rapid recurrence with distant metastases remains a significant challenge. Can
Externí odkaz:
https://doaj.org/article/a7c14905d0a540b290c52c0f37711b58
Autor:
Stephanie L. Tzetzo, Elliot D. Kramer, Hemn Mohammadpour, Minhyung Kim, Spencer R. Rosario, Han Yu, Melissa R. Dolan, Chetan C. Oturkar, Brian G. Morreale, Paul N. Bogner, Aimee B. Stablewski, Fernando J. Benavides, Craig M. Brackett, John M.L. Ebos, Gokul M. Das, Mateusz Opyrchal, Michael J. Nemeth, Sharon S. Evans, Scott I. Abrams
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109187- (2024)
Summary: Tissue-resident macrophages (TRMs) are abundant immune cells within pre-metastatic sites, yet their functional contributions to metastasis remain incompletely understood. Here, we show that alveolar macrophages (AMs), the main TRMs of the lu
Externí odkaz:
https://doaj.org/article/b0dead588580421280f878bb0ac7259a
Autor:
Kunle Odunsi, Takemasa Tsuji, Mark Long, Danuta Kozbor, Scott I Abrams, Emese Zsiros, A J Robert McGray, Jessie L Chiello, Kathryn Maraszek, Nicole Gaulin, Spencer R Rosario, Suzanne M Hess
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background Cancer immunotherapies can produce complete therapeutic responses, however, outcomes in ovarian cancer (OC) are modest. While adoptive T-cell transfer (ACT) has been evaluated in OC, durable effects are rare. Poor therapeutic efficacy is l
Externí odkaz:
https://doaj.org/article/9b49e6bc2cfa4280884bd9b7ea9e2876
Autor:
Elliot D. Kramer, Stephanie L. Tzetzo, Sean H. Colligan, Mary L. Hensen, Craig M. Brackett, Björn E. Clausen, Makoto M. Taketo, Scott I. Abrams
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
The main cause of malignancy-related mortality is metastasis. Although metastatic progression is driven by diverse tumor-intrinsic mechanisms, there is a growing appreciation for the contribution of tumor-extrinsic elements of the tumor microenvironm
Externí odkaz:
https://doaj.org/article/f762002b983b4170b33a8ba0a4439eaa
Autor:
Paul K Wallace, Thomas Schwaab, Scott I Abrams, Elizabeth A Repasky, Alexis Conway, Jason B Muhitch, Jacky Chow, Adil Khan, Madeline Gaudieri, Brianna J Wasik, Kah Teong Soh, Anurag K Singh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background Studies evaluating peripheral patient samples show radiation can modulate immune responses, yet the biological changes in human tumors particularly at the cellular level remain largely unknown. Here, we address how radiation treatment shap
Externí odkaz:
https://doaj.org/article/be083ad959af46eea3224d5aecd46e1e
Autor:
Donald I. Abrams, Andrew Weil
More and more people living with and beyond cancer seek integrative interventions to complement their conventional cancer care. This second edition of the highly successful Integrative Oncology provides the reader with the most updated information av
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Despite recent progress in therapeutic strategies, prognosis of metastatic triple-negative breast cancer (TNBC) remains dismal. Evidence suggests that the induction and activation of tumor-residing conventional type-1 dendritic cells (cDC1s)
Externí odkaz:
https://doaj.org/article/a47ce881037545fd9257a49e41ccbe12
Autor:
Sean H. Colligan, Andrea M. Amitrano, Robert A. Zollo, Jennifer Peresie, Elliot D. Kramer, Brian Morreale, Joseph Barbi, Prashant K. Singh, Han Yu, Jianmin Wang, Mateusz Opyrchal, David B. Sykes, Michael J. Nemeth, Scott I. Abrams
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
While immune checkpoint inhibitors (ICIs) have transformed the therapeutic landscape in oncology, they are effective in select subsets of patients. Efficacy may be limited by tumor-driven immune suppression, of which 1 key mechanism is the developmen
Externí odkaz:
https://doaj.org/article/0a0122b323af493baa53eae9ada9561e
Autor:
Jeffery A. Dusek, Qi Gao, Ryung S. Kim, Donald I. Abrams, Benjamin Kligler, Natalie L. Dyer, Kathryn Hansen, M. Diane McKee
Publikováno v:
Complementary Therapies in Medicine, Vol 71, Iss , Pp 102904- (2022)
Objective: To evaluate the real-world effectiveness of integrative medicine treatment on quality of life using the Patients Receiving Integrative Medicine Effectiveness Registry (PRIMIER). Design: A prospective, longitudinal, observational evaluation
Externí odkaz:
https://doaj.org/article/f0b3fc0e41904bfda32b67377a288056