Zobrazeno 1 - 7
of 7
pro vyhledávání: '"I A Heijnen"'
Publikováno v:
Journal of investigational allergologyclinical immunology. 32(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c9fcc8cb71268e91e1c794d2c4efc9
https://pubmed.ncbi.nlm.nih.gov/34160350
https://pubmed.ncbi.nlm.nih.gov/34160350
Autor:
I A Heijnen, L J Rijks, A Schiel, B Stockmeyer, H H van Ojik, M Dechant, T Valerius, T Keler, A L Tutt, M J Glennie, E A van Royen, P J Capel, J G van de Winkel
Publikováno v:
The Journal of Immunology. 159:5629-5639
Abs are able to induce inflammatory antitumor responses by recruiting IgG Fc receptor (FcgammaR)-bearing cytotoxic effector cells. We recently described the capacity of the high affinity FcgammaRI (CD64) to trigger cytotoxic activity of neutrophils (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24aa769022d78f08c755736be8f2dc14
https://doi.org/10.4049/jimmunol.159.11.5629
https://doi.org/10.4049/jimmunol.159.11.5629
Publikováno v:
Blood. 96(10)
CD64 (FcgammaRI) receptors represent highly potent trigger molecules for activated polymorphonuclear cells (PMN) and mediate lysis of a range of tumors in the presence of appropriate monoclonal antibodies. An huCD64 transgenic mouse model designed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22adb27d784d4f3fd9c00d99a6dc50ff
https://pubmed.ncbi.nlm.nih.gov/11071653
https://pubmed.ncbi.nlm.nih.gov/11071653
Autor:
G, Huls, I A, Heijnen, E, Cuomo, J, van der Linden, E, Boel, J G, van de Winkel, T, Logtenberg
Publikováno v:
Cancer research. 59(22)
We have constructed a recombinant, fully human IgA1 monoclonal antibody, UBS-54/IgA1, against the tumor-associated Ep-CAM molecule and compared its tumor-killing capacity with its IgG1 counterpart in in vitro assays. The data show that phage display-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b33e473498c0c7767f213d30133d21f
https://pubmed.ncbi.nlm.nih.gov/10582699
https://pubmed.ncbi.nlm.nih.gov/10582699
Autor:
W L, Hazenbos, I A, Heijnen, D, Meyer, F M, Hofhuis, C R, Renardel de Lavalette, R E, Schmidt, P J, Capel, J G, van de Winkel, J E, Gessner, T K, van den Berg, J S, Verbeek
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(6)
Previously, we have demonstrated that phagocytosis of IgG1-coated particles by macrophages in vitro is impaired by deletion of Fc gamma RIII in mice, suggesting that IgG1 may interact preferentially with Fc gamma RIII. In the present study, the biolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb136e6abe137058dc7d6f19c85a10f5
https://pubmed.ncbi.nlm.nih.gov/9743367
https://pubmed.ncbi.nlm.nih.gov/9743367
Autor:
B, Stockmeyer, T, Valerius, R, Repp, I A, Heijnen, H J, Bühring, Y M, Deo, J R, Kalden, M, Gramatzki, J G, van de Winkel
Publikováno v:
Cancer research. 57(4)
Immunotherapies directed to the proto-oncogene product HER-2/neu, which is overexpressed on a subset of breast and other carcinomas, currently receive considerable attention. We have investigated cell-mediated effector mechanisms of HER-2/neu antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::381598fd28104998ccae3bb314ff233b
https://pubmed.ncbi.nlm.nih.gov/9044847
https://pubmed.ncbi.nlm.nih.gov/9044847
Autor:
M J, van Vugt, I A, Heijnen, P J, Capel, S Y, Park, C, Ra, T, Saito, J S, Verbeek, J G, van de Winkel
Publikováno v:
Blood. 87(9)
Most Ig receptors exist as hetero-oligomeric complexes with separate ligand binding (alpha) and signal transducing (beta, gamma, or zeta) subunits. For Fc gamma RIIIa and Fc epsilon RI, association with the FcR gamma-chain is essential for surface ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08acd3e14937947c361a6aac864cfe37
https://pubmed.ncbi.nlm.nih.gov/8611682
https://pubmed.ncbi.nlm.nih.gov/8611682