Výsledky vyhledávání - "I A, Ramshaw"

IFN-γ Regulates Murine Interferon-Inducible T Cell Alpha Chemokine (I-TAC) Expression in Dendritic Cell Lines and during Experimental Autoimmune Encephalomyelitis (EAE)

Autor: N. H. R. Hamilton, J. L. Banyer, A. J. Hapel, S. Mahalingam, A. J. Ramsay, I. A. Ramshaw, S. A. Thomson

Publikováno v: Scandinavian Journal of Immunology. 55:171-177

The authors have analysed gliadin specific, CD4+ T cells isolated from small intestinal biopsies of 23 adult coeliac disease patients (20 on a gluten-free diet and three untreated) and nine control patients. The biopsies were stimulated ex vivo with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b25720a3da9088fc858f38f2a002065
https://doi.org/10.1046/j.1365-3083.1997.d01-93.x

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IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

Autor: D O Willenborg, S Fordham, C C Bernard, W B Cowden, I A Ramshaw

Publikováno v: The Journal of Immunology. 157:3223-3227

129/Sv mice are resistant to induction of experimental autoimmune encephalomyelitis (EAE) induced with myelin oligodendrocyte glycoprotein peptide (MOG35-55). Mice of this strain lacking the gene coding for the ligand-binding chain of the IFN-gamma r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1c9117e6e7e5f5ea2edce8674e2eb03
https://doi.org/10.4049/jimmunol.157.8.3223

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IFN-gamma, TNF, and IL-6 production by vaccinia virus immune spleen cells. An in vitro study

Autor: E A Carpenter, J Ruby, I A Ramshaw

Publikováno v: The Journal of Immunology. 152:2652-2659

The production of cytokines by virus immune spleen cells after in vitro restimulation was investigated. Vaccinia virus-primed spleen cells from CBA/H mice were stimulated in vitro with virus-infected UV-irradiated syngeneic cells. Both CD4+ and CD8+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::24d5e084db211e914042187030d65876
https://doi.org/10.4049/jimmunol.152.6.2652

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Immunobiology of infection with recombinant vaccinia virus encoding murine IL-2. Mechanisms of rapid viral clearance in immunocompetent mice

Autor: G Karupiah, C E Woodhams, R V Blanden, I A Ramshaw

Publikováno v: The Journal of Immunology. 147:4327-4332

CD8+ cytotoxic T (Tc) lymphocytes mediate recovery from vaccinia virus (VV) infection. In mice, anti-VV Tc cells are detectable on or after day 3 after infection, and cytolytic activity peaks between days 5 and 6. A rVV encoding murine IL-2, VV-hemag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b9c56442467c3f76cb496618f8e9031
https://doi.org/10.4049/jimmunol.147.12.4327

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Elevated natural killer cell responses in mice infected with recombinant vaccinia virus encoding murine IL-2

Autor: G Karupiah, B E Coupar, M E Andrew, D B Boyle, S M Phillips, A Müllbacher, R V Blanden, I A Ramshaw

Publikováno v: The Journal of Immunology. 144:290-298

The role of cytotoxic T cells and NK cells in the recovery of immunodeficient, athymic, nude mice infected with a recombinant vaccinia virus (VV) encoding murine IL-2 was investigated. Kinetic studies with the IL-2-encoding recombinant (VV-HA-IL2) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3827a57be174837b708d7cd5f09b36bf
https://doi.org/10.4049/jimmunol.144.1.290

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IFN-gamma regulates murine interferon-inducible T cell alpha chemokine (I-TAC) expression in dendritic cell lines and during experimental autoimmune encephalomyelitis (EAE)

Autor: N H R, Hamilton, J L, Banyer, A J, Hapel, S, Mahalingam, A J, Ramsay, I A, Ramshaw, S A, Thomson

Publikováno v: Scandinavian journal of immunology. 55(2)

Murine interferon-inducible T cell alpha chemokine (I-TAC) is a potent non-ELR Cys-X-Cys (CXC) chemokine that predominantly attracts activated T lymphocytes and binds to the receptor CXCR3. Using semiquantitative reverse transcription-polymerase chai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd87045e2cf4d0b168c2cc82413e056a
https://pubmed.ncbi.nlm.nih.gov/11896933

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Cytokines in innate and adaptive immunity

Autor: J L, Banyer, N H, Hamilton, I A, Ramshaw, A J, Ramsay

Publikováno v: Reviews in immunogenetics. 2(3)

Cytokines and chemokines are hormone-like messengers which act to regulate the development and expression of the broad array of immune responses that are mounted against a variety of pathogens. As such, they are critical determinants of the types of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d67c21d980e7bbbca947b00d5025181
https://pubmed.ncbi.nlm.nih.gov/11256745

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Induction of HIV-1-specific T-helper responses and type 1 cytokine secretion following therapeutic vaccination of macaques with a recombinant fowlpoxvirus co-expressing interferon-gamma

Autor: C J, Dale, A, Zhao, S L, Jones, D B, Boyle, I A, Ramshaw, S J, Kent

Publikováno v: Journal of medical primatology. 29(3-4)

Preventive and/or therapeutic vaccines against Human Immunodeficiency Virus (HIV-1) are urgently required. Induction of cellular immunity is favoured since these responses correlate with control of HIV-1. Recombinant fowlpoxvirus (FPV) vaccines encod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28f5dc425fc515b70ef1de7fe6a38008
https://pubmed.ncbi.nlm.nih.gov/11085586

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IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide

Autor: D O, Willenborg, S A, Fordham, M A, Staykova, I A, Ramshaw, W B, Cowden

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(10)

NO and IFN-gamma have normally been considered cytotoxic and proinflammatory molecules, respectively, in the setting of the central nervous system inflammatory disease autoimmune encephalomyelitis (EAE). Using mice lacking the ligand binding chain of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d85398d0e547e3495f6790c37276186
https://pubmed.ncbi.nlm.nih.gov/10553050

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