Výsledky vyhledávání - "I A, Liebson"

Buprenorphine's physical dependence potential: antagonist-precipitated withdrawal in humans

Autor: T, Eissenberg, M K, Greenwald, R E, Johnson, I A, Liebson, G E, Bigelow, M L, Stitzer

Publikováno v: The Journal of pharmacology and experimental therapeutics. 276(2)

Buprenorphine is a partial mu opioid agonist with demonstrated efficacy in the treatment of opioid dependence. One potential advantage of buprenorphine over full mu opioid agonists is its reported low physical dependence profile. This study systemati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30c1d9d55cf3d2c8f1ef63c2920d7dcf
https://pubmed.ncbi.nlm.nih.gov/8632309

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Buprenorphine effects in methadone-maintained volunteers: effects at two hours after methadone

Autor: E C, Strain, K L, Preston, I A, Liebson, G E, Bigelow

Publikováno v: The Journal of pharmacology and experimental therapeutics. 272(2)

Buprenorphine is an opioid partial agonist being developed for possible use in the treatment of opioid dependence. In a previous study up to 8 mg of buprenorphine administered 20 hr after a daily dose of methadone in methadone-maintained volunteers p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a88389c71f274709e3c3ed08110904c3
https://pubmed.ncbi.nlm.nih.gov/7853176

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Precipitated withdrawal by pentazocine in methadone-maintained volunteers

Autor: E C, Strain, K L, Preston, I A, Liebson, G E, Bigelow

Publikováno v: The Journal of pharmacology and experimental therapeutics. 267(2)

Pentazocine is a partial mu agonist opioid with one-half to one-sixth the parenteral analgesic potency of morphine. The purpose of this study was to characterize the effects of pentazocine in comparison to naloxone (an opioid antagonist), hydromorpho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab01d4497f78a5537c09cec5e223a37e
https://pubmed.ncbi.nlm.nih.gov/7504098

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Acute effects of buprenorphine, hydromorphone and naloxone in methadone-maintained volunteers

Autor: E C, Strain, K L, Preston, I A, Liebson, G E, Bigelow

Publikováno v: The Journal of pharmacology and experimental therapeutics. 261(3)

Buprenorphine is an opioid agonist-antagonist being evaluated for treatment of opioid dependence. This study characterized the effects of buprenorphine in comparison to naloxone, hydromorphone and saline, in methadone-dependent volunteers. In a resid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::70d30242f8ceaceaaf7dd1efa3546a9a
https://pubmed.ncbi.nlm.nih.gov/1376362

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Discrimination of agonist-antagonist opioids in humans trained on a two-choice saline-hydromorphone discrimination

Autor: K L, Preston, I A, Liebson, G E, Bigelow

Publikováno v: The Journal of pharmacology and experimental therapeutics. 261(1)

The stimulus properties of four opioid agonist-antagonists were assessed in postaddict volunteers trained in a two-choice drug discrimination procedure to discriminate between the effects of i.m. saline and hydromorphone (3 mg/70 kg). Behavioral, sub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c64d0f0b8b5a438048565171df1b302
https://pubmed.ncbi.nlm.nih.gov/1373189

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Relative abuse liability of lorazepam and diazepam: an evaluation in ‘recreational’ drug users

Autor: F R, Funderburk, R R, Griffiths, D R, McLeod, G E, Bigelow, A, Mackenzie, I A, Liebson, R, Nemeth-Coslett

Publikováno v: Drug and Alcohol Dependence. 22:215-222

The subjective, psychomotor and cognitive effects of oral doses of lorazepam (0, 1.5, 3 and 6 mg) and diazepam (0, 10, 20 and 40 mg) were studied under double-blind conditions in 14 volunteers with histories of ‘recreational’ benzodiazepine use/a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efba03af936bdd992500a9de16290e2d
https://doi.org/10.1016/0376-8716(88)90021-x

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Antagonist effects of nalbuphine in opioid-dependent human volunteers

Autor: K L, Preston, G E, Bigelow, I A, Liebson

Publikováno v: The Journal of pharmacology and experimental therapeutics. 248(3)

The subjective, physiological and behavioral effects of nalbuphine, an opioid mixed agonist/antagonist analgesic, naloxone and hydromorphone were studied on adult, male, methadone-dependent volunteers living on a clinical research ward. The purpose w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::858637b41072bb6b48ef98107dbd50d2
https://pubmed.ncbi.nlm.nih.gov/2467983

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