Zobrazeno 1 - 10
of 20
pro vyhledávání: '"I A, Kostanyan"'
Autor:
A. I. Autenshlus, A. V. Sosnina, E. S. Mikhailiva, A. P. Lykov, Yu. V. Tumanov, E. D. Danilanko, V. S. Samukov, I. A. Kostanyan, D. V. Morozov, M. M. Cherenkova, L. .A. Thvan, N. A. Varaksin
Publikováno v:
Медицинская иммунология, Vol 12, Iss 1-2, Pp 49-56 (2014)
Antibodies to leukemia differentiation factor (HLDF) in patients with gastrointestinal cancer Abstract. Patients with gastric cancer exhibit higher levels of IgG4-antibodies to human leukemia differentiation factor (HLDF), as compared with healthy in
Externí odkaz:
https://doaj.org/article/209c7f85a6db4c8a8c11135ce24f6dc0
Autor:
S. M. Dranitsyna, G. A. Zheltukhina, T. N. Lobanova, Marat O. Gallyamov, I. A. Kostanyan, V. E. Nebol'sin
Publikováno v:
Russian Journal of Bioorganic Chemistry. 32:179-190
A series of octa-hexapeptide fragments of HLDF and their conjugates with hemin were obtained by solid phase peptide synthesis. A relationship between the structure and the nuclease activity of the compounds was established. The effect of various fact
Publikováno v:
Pharmaceutical Chemistry Journal. 39:621-626
The key role of Bcl-2 (B-cell lymphoma) family proteins in programmed cell death (apoptosis) is reliably established, but particular molecular mechanisms of downregulation involving these anti-and pro-apoptotic proteins are still insufficiently clear
Autor:
Marat O. Gallyamov, I. A. Kostanyan, Alexei R. Khokhlov, S. M. Dranitsyna, V. E. Nebol'sin, T. N. Lobanova, G. A. Zheltukhina
Publikováno v:
Doklady Physical Chemistry. 405:253-256
In this work, the highly efficient cleavage of plasmid DNA by original synthetic biodegradable and biocompatible nucleases, conjugates of natural products, was studied by different physicochemical methods. The invoking of atomic force microscopy (AFM
Autor:
S. V. Litvinova, I. A. Kostanyan, V. V. Shul'govskii, Terebilina Nn, A. L. Kalyuzhnyi, Leonid F. Panchenko, V. V. Aristova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 135:133-135
We studied the effect of bioactive peptide HLDF-6 on functional activity of the endogenous antinociceptive system in the offspring of morphine-tolerant animals. Disturbances in this system included changes in the thermonociceptive threshold and enkep
Publikováno v:
Acta Naturae
The pigment epithelium-derived factor (PEDF) is a glycoprotein with a molecular weight of 50 kDa belonging to the noninhibitory serpin family. It regulates several physiological processes, such as stimulation of retinoblastoma cell differentiation in
Autor:
V. I. Knysh, S. G. Abbasova, Valery M. Lipkin, V. V. Prorokov, T. A. Britvin, N. E. Kushlinskii, A. G. Perevoshchikov, I. A. Kostanyan
Publikováno v:
Bulletin of Experimental Biology and Medicine. 131:361-363
Serum concentration of soluble Fas antigen (sFas) was measured in 60 normal subjects and 33 patients with colon cancer. The incidence of sFas detection and its serum content were higher in patients with colon cancer compared to normal subjects. No re
Autor:
N. E. Kushlinskii, I. A. Kostanyan, S. O. Nikogosyan, Arkady N. Murashev, N. F. Bagirova, Valery M. Lipkin, N. N. Trapeznikov, S. G. Abbasova, T. A. Britvin, Yu. N. Solov'ev, M. N. Obusheva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 127:296-298
Blood concentration of soluble Fas antigen is higher in patients with benign and malignant tumors in comparison with healthy subjects, which probably suggests its involvement into tumorigenesis.
Autor:
S. V. Litvinova, Leonid F. Panchenko, I. A. Kostanyan, V. V. Aristova, A. L. Kalyuzhnyi, N. N. Terebelina, V. V. Shul'govskii
Publikováno v:
Bulletin of experimental biology and medicine. 137(5)
Experiments were performed on rats with opium abuse induced by chronic administration of morphine in increasing doses. We studied the effect of HLDF-6 peptide on symptoms of naloxone abstinence. Repeated administration of HLDF-6 peptide in a dose of
Autor:
M A, Gruden, T B, Davudova, M, Malisauskas, V V, Zamotin, R D E, Sewell, N I, Voskresenskaya, I A, Kostanyan, V V, Sherstnev, L A, Morozova-Roche
Publikováno v:
Dementia and geriatric cognitive disorders. 18(2)
We have found an increased level of serum antibodies to the prefibrillar structures of both Abeta(25-35) peptide and human lysozyme in Alzheimer's disease (AD) patients compared to age-matched controls, indicating that autoimmunity is implicated in A