Výsledky vyhledávání - "I A, Drachkova"

Akademický článek

An experimental study of the effects of SNPs in the TATA boxes of the GRIN1, ASCL3 and NOS1 genes on interactions with the TATA-binding protein

Autor: E. B. Sharypova, I. A. Drachkova, I. V. Chadaeva, M. P. Ponomarenko, L. K. Savinkova

Publikováno v: Вавиловский журнал генетики и селекции, Vol 26, Iss 3, Pp 227-233 (2022)

The GRIN1, ASCL3, and NOS1 genes are associated with various phenotypes of neuropsychiatric disorders. For instance, these genes contribute to the development of schizophrenia, Alzheimer’s and Parkinson’s diseases, and epilepsy. These genes are a

Externí odkaz: https://doaj.org/article/a23192b3b2404920b465c541ec6bf998

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Akademický článek

Candidate SNP-markers altering TBP binding affinity for promoters of the Y-linked genes CDY2A, SHOX, and ZFY are lowering many indexes of reproductive potential in men

Autor: M. P. Ponomarenko, E. B. Sharypova, I. A. Drachkova, L. K. Savinkova, I. V. Chadaeva, D. A. Rasskazov, P. M. Ponomarenko, L. V. Osadchuk, A. V. Osadchuk

Publikováno v: Вавиловский журнал генетики и селекции, Vol 24, Iss 7, Pp 785-793 (2020)

Reproductive potential is the most important conditional indicator reflecting the ability of individuals in a population to reproduce, survive and develop under optimal environmental conditions. As for humans, the concept of reproductive potential ca

Externí odkaz: https://doaj.org/article/837b58a0d0bd4f98a5e1fd7881fe8950

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Akademický článek

Сandidate SNP-markers of rheumatoid arthritis that can significantly alter the affinity of the TATA-binding protein for human gene promoters

Autor: I. V. Chadaeva, D. A. Rasskazov, E. B. Sharypova, I. A. Drachkova, E. A. Oshchepkova, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko, N. A. Kolchanov, V. A. Kozlov

Publikováno v: Вавиловский журнал генетики и селекции, Vol 23, Iss 8, Pp 1047-1058 (2020)

Rheumatoid polyarthritis (RA) is an autoimmune disease with autoantibodies, including antibodies to citrullant antigens and proinflammatory cytokines, such as TNF-α and IL-6, which are involved in the induction of chronic synovitis, bone erosion, fo

Externí odkaz: https://doaj.org/article/a4d34014ce894a0184ae1fa2ee6de0e3

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Akademický článek

AN EXPERIMENTAL STUDY OF THE EFFECT OF RARE POLYMORPHISMS OF HUMAN HBB, HBD AND F9 PROMOTER TATA BOXES ON THE KINETICS OF INTERACTION WITH THE TATA-BINDING PROTEIN

Autor: E. B. Sharypova, I. A. Drachkova, E. V. Kashina, D. A. Rasskazov, P. M. Ponomarenko, M. P. Ponomarenko, N. А. Kolchanov, L. K. Savinkova

Publikováno v: Вавиловский журнал генетики и селекции, Vol 22, Iss 1, Pp 145-152 (2018)

Human genes HBB, HBD and F9 belong to the hematopoiesis system. The deficiency or excess of these genes’ products is the cause of hereditary thalassemias of various severity and haemophilia B Leyden. Previously, it was shown that a number of annota

Externí odkaz: https://doaj.org/article/cfa553e1b2a94aae8654a585b48f74ed

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Akademický článek

Prediction and verification of the influence of the rs367781716 SN P on the interaction of ТАТА -binding protein with the promoter of the human АВСА9 gene

Autor: O. V. Arkova, I. A. Drachkova, T. V. Arshinova, D. A. Rasskazov, V. V. Suslov, P. M. Ponomarenko, M. P. Ponomarenko, N. A. Kolchanov, L. K. Savinkova

Publikováno v: Вавиловский журнал генетики и селекции, Vol 19, Iss 6, Pp 675-681 (2016)

The high-throughput sequencing project “1 000 Genomes” made it possible to catalog and utilize genetic loci and single nucleotide polymorphisms (SNPs) in medicine. Analysis of SNP markers (significantly frequent differences of individual genomes

Externí odkaz: https://doaj.org/article/716e271f58514d208139b439c432845b

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Akademický článek

SURFACE PLASMON RESONANCE STUDY OF THE INTERACTION BETWEEN THE HUMAN TATA-BOX BINDING PROTEIN AND THE TATA ELEMENT OF THE NOS2A GENE PROMOTER

Autor: I. A. Drachkova, S. V. Shekhovtsov, S. E. Peltek, P. M. Ponomarenko, T. V. Arshinova, M. P. Ponomarenko, T. I. Merkulova, L. K. Savinkova, N. A. Kolchanov

Publikováno v: Вавиловский журнал генетики и селекции, Vol 16, Iss 2, Pp 391-396 (2014)

Interaction ofthe TATA-binding protein (ТВР) with the TATA box and formation ofthe TBP/TATA complex is the first step in the transcription complex assembly and the central event in transcription regulation. It is known that some single nucleotide

Externí odkaz: https://doaj.org/article/5b1df5d30d8647e48288dfa0534a7098

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An experimental study of the effects of SNPs in the TATA boxes of the GRIN1, ASCL3 and NOS1 genes on interactions with the TATA-binding protein

Autor: E B, Sharypova, I A, Drachkova, I V, Chadaeva, M P, Ponomarenko, M P, Savinkova

Publikováno v: Vavilovskii zhurnal genetiki i selektsii. 26(3)

The GRIN1, ASCL3, and NOS1 genes are associated with various phenotypes of neuropsychiatric disorders. For instance, these genes contribute to the development of schizophrenia, Alzheimer's and Parkinson's diseases, and epilepsy. These genes are also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::80c07ccf92a7a7cbb3a0beb08a8643d1
https://pubmed.ncbi.nlm.nih.gov/35774364

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Candidate SNP Markers of Atherosclerosis That May Significantly Change the Affinity of the TATA-Binding Protein for the Human Gene Promoters

Autor: I. A. Drachkova, Ekaterina Sharypova, D. A. Rasskazov, Evgeniya Oshchepkova, Nikolay A. Kolchanov, Mikhail P. Ponomarenko, Irina Chadaeva, Ludmila Savinkova, P. M. Ponomarenko

Publikováno v: Russian Journal of Genetics. 55:1137-1151

Atherosclerosis (AS) and AS-related pathologies such as coronary heart disease, myocardial infarction, angina pectoris, and stroke are the leading causes of death in the world. The atherogenesis can be influenced by many factors, in particular, overw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c480228c06fb3731f50fa0c2ce2953e3
https://doi.org/10.1134/s1022795419090114

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A Bioinformatics Model of Human Diseases on the Basis of Differentially Expressed Genes (of Domestic versus Wild Animals) That Are Orthologs of Human Genes Associated with Reproductive-Potential Changes

Autor: Mikhail P. Ponomarenko, Ekaterina Sharypova, Nikolay A. Kolchanov, Anton Bogomolov, I. A. Drachkova, Dmitry Oshchepkov, L. V. Osadchuk, A. V. Osadchuk, D. A. Rasskazov, Irina Chadaeva, Ludmila Savinkova, Gennady Vasiliev, P. M. Ponomarenko

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 5
International Journal of Molecular Sciences, Vol 22, Iss 2346, p 2346 (2021)

Earlier, after our bioinformatic analysis of single-nucleotide polymorphisms of TATA-binding protein-binding sites within gene promoters on the human Y chromosome, we suggested that human reproductive potential diminishes during self-domestication. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af26bda40c565dd9937d2b4e2efc0bd5

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Disruptive natural selection by male reproductive potential prevents underexpression of protein-coding genes on the human Y chromosome as a self-domestication syndrome

Autor: Semyon Kolmykov, Ekaterina Sharypova, A. V. Osadchuk, D. A. Rasskazov, Elena V. Ignatieva, Anton Bogomolov, L. V. Osadchuk, Dmitry Oshchepkov, Kleshchev Ma, Gennady V. Vasiliev, Natalia Gutorova, Mikhail P. Ponomarenko, P. M. Ponomarenko, I. A. Drachkova, Irina Chadaeva, Ludmila Savinkova

Publikováno v: BMC Genetics
BMC Genetics, Vol 21, Iss S1, Pp 1-17 (2020)

Background In population ecology, the concept of reproductive potential denotes the most vital indicator of chances to produce and sustain a healthy descendant until his/her reproductive maturity under the best conditions. This concept links quality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5b0e7d560e4d6b4d659f9ea097ad3b
https://doi.org/10.1186/s12863-020-00896-6

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