Zobrazeno 1 - 10
of 46
pro vyhledávání: '"I‐Ying Kuo"'
Autor:
Pei‐Wen Lin, Man‐Ling Chu, Yu‐Wen Liu, Yu‐Cing Chen, Yao‐Hsiang Shih, Sheng‐Hui Lan, Shang‐Ying Wu, I‐Ying Kuo, Hong‐Yi Chang, Hsiao‐Sheng Liu, Ying‐Ray Lee
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 642-649 (2024)
Abstract Autophagy can be classified as degradative and secretory based on distinct functions. The small GTPase proteins Rab8a and Rab37 are responsible for secretory autophagy‐mediated exocytosis of IL‐1β, insulin, and TIMP1 (tissue inhibitor o
Externí odkaz:
https://doaj.org/article/e258c7ae7ddd4ed3a3137a5a976dbe9c
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Ubiquitination and deubiquitination are important forms of posttranslational modification that govern protein homeostasis. Deubiquitinating enzymes (DUBs), a protein superfamily consisting of more than 100 members, deconjugate ubiquitin chai
Externí odkaz:
https://doaj.org/article/be832de6c2344d1585efd96155d54739
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-20 (2024)
Abstract Background Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor expressed on the surface of T cells. High expression of PD-1 leads to T-cell dysfunction in the tumor microenvironment (TME). However, the mechanism of intrac
Externí odkaz:
https://doaj.org/article/f40fd3e99c6c4fc29da14694cc63407c
Autor:
Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-17 (2023)
Abstract Aberrant overexpression or activation of EGFR drives the development of non-small cell lung cancer (NSCLC) and acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) by secondary EGFR mutations or c-MET amplification/activation remain
Externí odkaz:
https://doaj.org/article/aaf04d699c2f45f6a88e5341ad07b036
Autor:
Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9922c5b5578240c4ba3a59bfacda25c3
Autor:
Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, I-Ying Kuo, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan, Yi-Ching Wang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is the sixth leading cause of cancer-associated death worldwide with a dismal overall 5-year survival rate of less than 20%. The standard first-line therapy for advanced ESCC is concomitan
Externí odkaz:
https://doaj.org/article/30217219feb34a9f871a60222942de23
Autor:
I-Ying Kuo, Yu-Lin Huang, Chien-Yu Lin, Chien-Hsun Lin, Wei-Lun Chang, Wu-Wei Lai, Yi-Ching Wang
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-14 (2019)
Abstract Background Prognosis of esophageal squamous cell carcinoma (ESCC) patients is poor and the concurrent chemoradiation therapy (CCRT) provided to ESCC patients often failed due to resistance. Therefore, development of biomarkers for predicting
Externí odkaz:
https://doaj.org/article/b8627b0348134ae5a2634eff53ad8a20
Autor:
Kuang-Tzu Huang, I-Ying Kuo, Ming-Chao Tsai, Chun-Hsien Wu, Li-Wen Hsu, Li-Yu Chen, Chao-Pin Kung, Yu-Fan Cheng, Shigeru Goto, Yu-Wei Chou, Chao-Long Chen, Chih-Che Lin, Kuang-Den Chen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 274-283 (2017)
Hepatocellular carcinoma (HCC) is one of the most common and aggressive malignancies worldwide. Treatment outcomes remain poor mainly due to lack of good diagnostic/prognostic markers and limited therapeutic strategies. We previously characterized ab
Externí odkaz:
https://doaj.org/article/48e5dc56d831470086092efeab740567
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-26 (2022)
Abstract All cells in the changing tumor microenvironment (TME) need a class of checkpoints to regulate the balance among exocytosis, endocytosis, recycling and degradation. The vesicular trafficking and secretion pathways regulated by the small Rab
Externí odkaz:
https://doaj.org/article/f3303bda222b456e8173532701dfca56
Autor:
I-Ying Kuo, 郭怡瑩
102
The conglomerates played an important role in the economic development in Taiwan. The local conglomerates in Taiwan established subsidiaries through horizontal integration, vertical integration, and diversification. In the expansion process,
The conglomerates played an important role in the economic development in Taiwan. The local conglomerates in Taiwan established subsidiaries through horizontal integration, vertical integration, and diversification. In the expansion process,
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/5f3xuu
