Výsledky vyhledávání - "Işıl Nihan KORKMAZ"

Akademický článek

Santa Maria armudu püresinde LOX aktivitesi üzerine bazı katkı maddelerinin inhibisyon etkileri

Autor: Ömer İrfan Küfrevioğlu, Işıl Nihan Korkmaz, Arzu Öztürk Kesebir

Publikováno v: Journal of Ata-Chem, Vol 2, Iss 1, Pp 35-39 (2022)

Lipoksigenaz (EC 1.13.11.34.; LOX ) enzimleri; yapısında iki ya da daha fazla doymamış bağ bulunduran yağ asitlerini oksitleyen, yapılarında hem grubu bulundurmayan demir taşıyıcı dioksigenazlardır. LOX'lar bitkiler, hayvan dokuları ve

Externí odkaz: https://doaj.org/article/7b5d9f4ea5a84809982b001b32f5abf6

Zobrazit plný text záznamu

Synthesis and Anticancer Potential of New Hydroxamic Acid Derivatives as Chemotherapeutic Agents

Autor: Işıl Nihan Korkmaz, Hasan Özdemir

Publikováno v: Applied Biochemistry and Biotechnology. 194:6349-6366

Histone deacetylase (HDAC) inhibitors have been shown to induce differentiation, cell cycle arrest, and apoptosis due to their low toxicity, inhibiting migration, invasion, and angiogenesis in many cancer cells. Studies show that hydroxamic acids are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e43c0f32780d1c2450edb9e0ea68385
https://doi.org/10.1007/s12010-022-04107-z

Zobrazit plný text záznamu

In Vitro Inhibition Effects of 2-Amino Thiazole Derivatives on Lactoperoxidase Enzyme Activity

Autor: Işıl Nihan KORKMAZ

Publikováno v: Volume: 43, Issue: 1 33-37
Cumhuriyet Science Journal

Lactoperoxidase (LPO E.C. 1.11.1.7) is a member of the peroxidase family and is an important glycoprotein containing heme group in its structure and showing the antimicrobial effect on disease causing microorganisms in the digestive system of newborn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02375283c24b9463d12b4e78c7578989
https://doi.org/10.17776/csj.1017247

Zobrazit plný text záznamu

Structure‐Activity Relationship of Methyl 4‐Aminobenzoate Derivatives as Being Drug Candidate Targeting Glutathione Related Enzymes: in Vitro and in Silico Approaches

Autor: Işıl Nihan Korkmaz, Uğur Güller, Ramazan Kalın, Hasan Özdemir, Ömer İrfan Küfrevioğlu

Publikováno v: Chemistry & Biodiversity. 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a6cec06bdcb308d2486a80049e31bde
https://doi.org/10.1002/cbdv.202201220

Zobrazit plný text záznamu

Methyl benzoate derivatives: in vitro Paraoxonase 1 inhibition and in silico studies

Autor: Işıl Nihan Korkmaz, Cüneyt Türkeş, Yeliz Demir, Hasan Özdemir, Şükrü Beydemir

Publikováno v: Journal of biochemical and molecular toxicologyREFERENCES. 36(10)

Paraoxonase 1 (PON1) can metabolize some compounds such as aromatic carboxylic acid and unsaturated aliphatic esters, arylesters, cyclic carbonate, plucuronide drugs, some carbamate insecticide classes, nerve gases, and lactone compounds. Methyl benz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa9525ca6b25f6054b20843a33fe4bf
https://pubmed.ncbi.nlm.nih.gov/35708184

Zobrazit plný text záznamu

2-Amino thiazole derivatives as inhibitors of some metabolic enzymes: An in vitro and in silico study

Autor: Işıl Nihan KORKMAZ

Publikováno v: Biotechnology and applied biochemistryREFERENCES.

The thiazole derivatives are desirable compounds in the evaluation of their biological activities such as antiprotozoal antibacterial, antifungal, antituberculosis. Considering the medical application potential of 2-amino thiazole compounds, we aimed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23d53a16855a5c6e0c722d502abdede
https://pubmed.ncbi.nlm.nih.gov/35857901

Zobrazit plný text záznamu

Biological evaluation and in silico study of benzohydrazide derivatives as paraoxonase 1 inhibitors

Autor: Işıl Nihan Korkmaz, Cüneyt Türkeş, Yeliz Demir, Aykut Öztekin, Hasan Özdemir, Şükrü Beydemir

Serum paraoxonase 1 (PON1) is found in all mammalian species and is a calcium-dependent hydrolytic enzyme. PON1 hydrolyze several substrates, including carbonates, esters, and organophosphates. In the current study, we aimed to investigate the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d03ee2c36be8bba9fffe430cdde15ae
https://hdl.handle.net/20.500.12501/2642

Zobrazit plný text záznamu

In vitro Inhibition Profiles and Molecular Docking Analysis of Benzohydrazide Derivatives on Red Blood Cell Carbonic Anhydrases Isozymes

Autor: Pınar Güller, Işıl Nihan Korkmaz, Ramazan Kalın, Aykut Öztekin, Hasan Özdemir

Background: Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes that contain zinc ions on the active side and convert carbon dioxide to bicarbonate in metabolism. Human CA-I and CA-II, which are the most abundant CA isozymes in erythrocytes, hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f925b953fd70b8931a6c5c8f772a46
https://hdl.handle.net/20.500.12501/3062

Zobrazit plný text záznamu

A New Affinity Matrixe Synthesized from Aminobenzohydrazide Derivatives for Purification of Lactoperoxidase Enzyme

Autor: Neslihan Macit Kavaz, Deniz Erel, Işıl Nihan Korkmaz, Serpil Gerni, Nurgül Abul, Songül Bayrak, Zeynep Köksal, Ramazan Kalın, Aykut Öztekin, Hasan Özdemir

In this study, a new affinity process was developed for the purification of Lactoperoxidase with synthesized sixteen aminobenzohydrazide derivatives. For this purpose, ligands were covalently bound to CNBr-activated Sepharose-4B-L-tyrosine matrix and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a88584cf934d18974c47615f3b963a0
https://hdl.handle.net/20.500.12501/2664

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání