In silico discovery of diagnostic/vaccine candidate antigenic epitopes and a multi-epitope peptide vaccine (NaeVac) design for the brain-eating amoeba Naegleria fowleri causing human meningitis.

Autor: Köseoğlu AE; Duisburg-Essen University, Faculty of Chemistry, Department of Environmental Microbiology and Biotechnology, Essen, Germany. Electronic address: ahmetefekoseoglu@gmail.com., Özgül F; Biruni University, Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, Istanbul, Turkey., Işıksal EN; Biruni University, Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, Istanbul, Turkey; Biruni University, Faculty of Pharmacy, Department of Pharmacy, Istanbul, Turkey., Şeflekçi Y; Biruni University, Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, Istanbul, Turkey., Tülümen D; Biruni University, Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, Istanbul, Turkey., Özgültekin B; Bogaziçi University, Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, Istanbul, Turkey., Deniz Köseoğlu G; Ruhr-University Bochum, Experimental Eye Research Institute, Bochum, Germany., Özyiğit S; Biruni University, Faculty of Engineering and Natural Sciences, Department of Biomedical Engineering, Istanbul, Turkey., Ihlamur M; Biruni University, Vocational School, Department of Electronics and Automation, Istanbul, Turkey; Yıldız Technical University, Graduate School of Science and Engineering, Department of Bioengineering, Istanbul, Turkey., Ekenoğlu Merdan Y; Biruni University, Faculty of Medicine, Department of Medical Microbiology, Istanbul, Turkey.

Publikováno v: Gene [Gene] 2024 Apr 15; Vol. 902, pp. 148192. Date of Electronic Publication: 2024 Jan 20.