Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Iñigo MA"'
Autor:
Rodrigo Berzaghi, Kristian Gundersen, Brede Dille Pedersen, Amalie Utne, Nannan Yang, Turid Hellevik, Inigo Martinez-Zubiaurre
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionCancer-associated fibroblasts (CAFs) are abundant and influential elements of the tumor microenvironment (TME), giving support to tumor development in multiple ways. Among other mechanisms, CAFs are important regulators of immunological p
Externí odkaz:
https://doaj.org/article/66bc123438cb49349ab92b11292f7c57
Autor:
Elizabeth J. Radford, Hong-Kee Tan, Malin H. L. Andersson, James D. Stephenson, Eugene J. Gardner, Holly Ironfield, Andrew J. Waters, Daniel Gitterman, Sarah Lindsay, Federico Abascal, Iñigo Martincorena, Anna Kolesnik-Taylor, Elise Ng-Cordell, Helen V. Firth, Kate Baker, John R. B. Perry, David J. Adams, Sebastian S. Gerety, Matthew E. Hurles
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Loss-of-function of DDX3X is a leading cause of neurodevelopmental disorders (NDD) in females. DDX3X is also a somatically mutated cancer driver gene proposed to have tumour promoting and suppressing effects. We perform saturation genome edi
Externí odkaz:
https://doaj.org/article/787606f0736b45d2b045e1283e0cd595
Autor:
Jenny Andrea Arévalo-Romero, Gina López-Cantillo, Sara Moreno-Jiménez, Íñigo Marcos-Alcalde, David Ros-Pardo, Bernardo Armando Camacho, Paulino Gómez-Puertas, Cesar A. Ramírez-Segura
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10802 (2024)
The COVID-19 pandemic has overwhelmed healthcare systems and triggered global economic downturns. While vaccines have reduced the lethality rate of SARS-CoV-2 to 0.9% as of October 2024, the continuous evolution of variants remains a significant publ
Externí odkaz:
https://doaj.org/article/b72004d50b8f4d53921cbb316dda87f6
Publikováno v:
Cancer Reports, Vol 7, Iss 3, Pp n/a-n/a (2024)
Abstract Background Cancer‐associated fibroblasts (CAFs) consist of heterogeneous connective tissue cells and are often constituting the most abundant cell type in the tumor stroma. Radiation effects on tumor stromal components like CAFs in the con
Externí odkaz:
https://doaj.org/article/7d650147106d4c9eb7e1c822b8934aad
Autor:
Víctor Alía Navarro, Íñigo Martínez Delfrade, Belén De Frutos González, Blanca Morón García, Ana María Barrill Corpa, Pilar Sotoca Rubio, Beatriz Peñas García, Ana Ferrer Gómez, Cristian Perna Monroy, Reyes Ferreiro Monteagudo
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 8426-8433 (2023)
Extrapulmonary small-cell carcinoma (SCC) is a rare neoplasm that shares certain features with its pulmonary counterpart and occurs predominantly in the gastrointestinal tract (GIT). It is a high-grade and poorly differentiated neuroendocrine tumor,
Externí odkaz:
https://doaj.org/article/7ebdca37fd9e4d458a3fe4f20eb24223
Autor:
Kim Wong, Federico Abascal, Latasha Ludwig, Heike Aupperle-Lellbach, Julia Grassinger, Colin W. Wright, Simon J. Allison, Emma Pinder, Roger M. Phillips, Laura P. Romero, Arnon Gal, Patrick J. Roady, Isabel Pires, Franco Guscetti, John S. Munday, Maria C. Peleteiro, Carlos A. Pinto, Tânia Carvalho, João Cota, Elizabeth C. Du Plessis, Fernando Constantino-Casas, Stephanie Plog, Lars Moe, Simone de Brot, Ingrid Bemelmans, Renée Laufer Amorim, Smitha R. Georgy, Justina Prada, Jorge del Pozo, Marianne Heimann, Louisiane de Carvalho Nunes, Outi Simola, Paolo Pazzi, Johan Steyl, Rodrigo Ubukata, Peter Vajdovich, Simon L. Priestnall, Alejandro Suárez-Bonnet, Franco Roperto, Francesca Millanta, Chiara Palmieri, Ana L. Ortiz, Claudio S. L. Barros, Aldo Gava, Minna E. Söderström, Marie O’Donnell, Robert Klopfleisch, Andrea Manrique-Rincón, Inigo Martincorena, Ingrid Ferreira, Mark J. Arends, Geoffrey A. Wood, David J. Adams, Louise van der Weyden
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-29 (2023)
Abstract Background In humans, muscle-invasive bladder cancer (MIBC) is highly aggressive and associated with a poor prognosis. With a high mutation load and large number of altered genes, strategies to delineate key driver events are necessary. Dogs
Externí odkaz:
https://doaj.org/article/7c66e401481649aaa960de808d382f15
Autor:
María San-Román-Gil, Iñigo Martínez-Delfrade, Víctor Albarrán-Fernández, Patricia Guerrero-Serrano, Javier Pozas-Pérez, Jesús Chamorro-Pérez, Diana Rosero-Rodríguez, Pilar Sotoca-Rubio, Ana Maria Barrill-Corpa, Víctor Alia-Navarro, Carlos González-Merino, Coral García-de-Quevedo-Suero, Victoria López, Ignacio Ruz-Caracuel, Cristian Perna-Monroy, Reyes Ferreiro-Monteagudo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immunotherapy has demonstrated a role in the therapeutic landscape of a small subset of patients with colorectal carcinoma (CRC) that harbor a microsatellite instability (MSI-H) status due to a deficient DNA mismatch repair (dMMR) system. The remarka
Externí odkaz:
https://doaj.org/article/764e50597193429a803f3c4afe79992e
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background The primary goal of radiotherapy (RT) is to induce cellular damage on malignant cells; however, it is becoming increasingly recognized the important role played by the tumor microenvironment (TME) in therapy outcomes. Therapeutic
Externí odkaz:
https://doaj.org/article/d008b15aabb5487aa893540f5274f7c2
Autor:
Iñigo Martínez de Alegría, Iñigo Rozas Holgado, Edorta Ibarra, Eider Robles, José Luís Martín
Publikováno v:
Energies, Vol 17, Iss 10, p 2305 (2024)
Unmanned underwater vehicles (UUVs) are key technologies to conduct preventive inspection and maintenance tasks in offshore renewable energy plants. Making such vehicles autonomous would lead to benefits such as improved availability, cost reduction
Externí odkaz:
https://doaj.org/article/8e1e6bc549a046f08788214232c41bc3
Autor:
Jesús David Urbano-Gámez, Cinzia Guzzi, Manuel Bernal, Juan Solivera, Iñigo Martínez-Zubiaurre, Carlos Caro, María Luisa García-Martín
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5213 (2024)
The application of metal-based nanoparticles (mNPs) in cancer therapy and diagnostics (theranostics) has been a hot research topic since the early days of nanotechnology, becoming even more relevant in recent years. However, the clinical translation
Externí odkaz:
https://doaj.org/article/3590ccaf06d14886b520b9f7175e1157