Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Iñigo Casafont"'
Autor:
Jorge Mata-Garrido, Yao Xiang, Yunhua Chang-Marchand, Caroline Reisacher, Elisabeth Ageron, Ida Chiara Guerrera, Iñigo Casafont, Aurelia Bruneau, Claire Cherbuy, Xavier Treton, Anne Dumay, Eric Ogier-Denis, Eric Batsché, Mickael Costallat, Gwladys Revêchon, Maria Eriksson, Christian Muchardt, Laurence Arbibe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
This study reports reduced expression of the chromatin and splicing regulator HP1γ in inflammatory bowel disease (IBD) and shows that HP1γ protects against pervasive RNA splicing leading to toxic mRNA products detected in IBD, like progerin.
Externí odkaz:
https://doaj.org/article/cd62808a02c4443c8de8c01333a7ee93
Autor:
Jorge Mata-Garrido, Laura Frizzi, Thien Nguyen, Xiangyan He, Yunhua Chang-Marchand, Yao Xiang, Caroline Reisacher, Iñigo Casafont, Laurence Arbibe
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7347 (2023)
Chronic inflammatory processes in the intestine result in serious conditions such as inflammatory bowel disease (IBD) and cancer. An increased detection of cytoplasmic DNA sensors has been reported in the IBD colon mucosa, suggesting their contributi
Externí odkaz:
https://doaj.org/article/af20f9fa78fd4eaca5993a9c6bca71c4
Autor:
Jorge Mata-Garrido, Olga Tapia, Iñigo Casafont, Maria T. Berciano, Ana Cuadrado, Miguel Lafarga
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-15 (2018)
Abstract Neurons are highly vulnerable to DNA damage induced by genotoxic agents such as topoisomerase activity, oxidative stress, ionizing radiation (IR) and chemotherapeutic drugs. To avert the detrimental effects of DNA lesions in genome stability
Externí odkaz:
https://doaj.org/article/8b8d28ba966c4b3087b36cc2fe5f69dd
Autor:
Rocío Bengoechea, Olga Tapia, Iñigo Casafont, José Berciano, Miguel Lafarga, María T. Berciano
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 1, Pp 118-129 (2012)
Nuclear speckles are essential nuclear compartments involved in the assembly, delivery and recycling of pre-mRNA processing factors, and in the post-transcriptional processing of pre-mRNAs. Oculopharyngeal muscular dystrophy (OPMD) is caused by a sma
Externí odkaz:
https://doaj.org/article/baadb5819e514ebdb57ed557f8b1bed9
Autor:
Nuria T. Villagra, Joaquin Navascues, Iñigo Casafont, J. Fernando Val-Bernal, Miguel Lafarga, Maria T. Berciano
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 1, Pp 181-193 (2006)
It is well known that the cell nucleus is organized in structural and functional compartments involved in transcription, RNA processing and protein modifications such as conjugation with SUMO-1 and proteolysis. Promyelocytic leukaemia (PML) bodies ar
Externí odkaz:
https://doaj.org/article/63d6e55f15fc48b7b828987dad2f92bf
Autor:
Nuria T Villagrá, José Berciano, Marcos Altable, Joaquı́n Navascués, Iñigo Casafont, Miguel Lafarga, Marı́a T Berciano
Publikováno v:
Neurobiology of Disease, Vol 16, Iss 1, Pp 158-168 (2004)
Acute inflammatory demyelinating polyneuropathy (AIDP) is a type of Guillain–Barré syndrome (GBS) characterized by primary nerve demyelination sometimes with secondary axonal degeneration. Studies on the fine structure of dorsal root ganglia in AI
Externí odkaz:
https://doaj.org/article/dac1c8243c8f4f14bf7330386eb0defc
Autor:
Lorena García-Hevia, Nuria Terán, Juan Gallo, Jessica Oliveira, Mónica L. Fanarraga, Iñigo Casafont, Manuel Bañobre-López
Publikováno v:
Bioact Mater . 2021 Jun 17;8:153-164
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Bioactive Materials
Bioactive Materials, Vol 8, Iss, Pp 153-164 (2022)
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Bioactive Materials
Bioactive Materials, Vol 8, Iss, Pp 153-164 (2022)
Nowadays, a number of promising strategies are being developed that aim at combining diagnostic and therapeutic capabilities into clinically effective formulations. Thus, the combination of a modified release provided by an organic encapsulation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb1386f24b3b03e1157deaf03bd645c
http://hdl.handle.net/10902/23773
http://hdl.handle.net/10902/23773
Autor:
Pena-Alonso, Emma, Rodrigo, Juan Pablo, Parra, Iñigo Casafont, Pedrero, Juana Maria Garcia, Meana, Maria Victoria Gonzalez, Nieto, Carlos Suarez, Fresno, Manuel F., Morgan, Reginald O., Fernandez, M. Pilar
Publikováno v:
In Cancer Letters 2008 263(1):89-98
Autor:
Iñigo Casafont, Rafael Valiente, Lorena García-Hevia, Mónica L. Fanarraga, Juan C. Villegas, Jesús González, Fidel Fernández
Publikováno v:
Advanced Healthcare Materials 2016, 5, 1080-1087
Understanding the molecular mechanisms underlying the biosynthetic interactions between particular nanomaterials with specific cells or proteins opens new alternatives in nanomedicine and nanotoxicology. Multiwalled carbon nanotubes (MWCNTs) have lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233f4e58322aad0baf510c7ef890362f
https://doi.org/10.1002/adhm.201500753
https://doi.org/10.1002/adhm.201500753
Autor:
Maria T. Berciano, Iñigo Casafont, Miguel Lafarga, Vanesa Lafarga, Jorge Mata-Garrido, Ana Palanca
Publikováno v:
Molecular Neurobiology. 53:6799-6808
Neurons are highly vulnerable to genotoxic agents. To restore genome integrity upon DNA lesions, neurons trigger a DNA damage response (DDR) that requires chromatin modifications and transcriptional silencing at DNA damage sites. To study the reorgan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3177a3f51b195805f3a747fbc9e0a33a
https://doi.org/10.1007/s12035-015-9565-8
https://doi.org/10.1007/s12035-015-9565-8