Simulación de poblaciones celulares en dispositivos Organ-On-Chip: de los modelos clásicos a las simulaciones guiadas por datos

Autor: Teodora Randelovic, Mohamed Hamdy Doweidar, Jacobo Ayensa-Jiménez, Marina Pérez-Aliacar, Iñaki Ochoa, Manuel Doblaré, Sara Oliván

Publikováno v: Jornada de Jóvenes Investigadores del I3A. 6

Los microentornos celulares multi fenotípicos que se reproducen en dispositivos microfluídicos Organ-On-Chip son sistemas biológicos extremadamente complejos de modelar. Para diferentes poblaciones celulares, se deben considerar las interacciones

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bc7b8bf8522258a8b2237c1217b8abe
https://doi.org/10.26754/jji-i3a.201802850

Thermoplastic elastomer with advanced hydrophilization and bonding performances for rapid (30 s) and easy molding of microfluidic devices

Autor: Cecile M. Perrault, David Olea Duplan, Luis J. Fernández, Pei-Yun Jenny Wu, Clara Alcaine, Emmanuel Roy, Damien Coudreuse, Olaf Mercier, Iñaki Ochoa, Julie Lachaux, Blanca Gómez-Escoda

Publikováno v: Lab on a Chip
Lab on a Chip, Royal Society of Chemistry, 2017, 17 (15), pp.2581--2594. ⟨10.1039/c7lc00488e⟩
Lab on a Chip, 2017, 17 (15), pp.2581--2594. ⟨10.1039/c7lc00488e⟩

International audience; One of the most important areas of research on microfluidic technologies focuses on the identification and characterisation of novel materials with enhanced properties and versatility. Here we present a fast, easy and inexpens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd22cf1ba6d24d6dc7a2fcc109b88634
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01578073

Engineering glioblastoma microenvironment in a chip to study cell response

Autor: Jose M. Ayuso, Manuel Doblaré, María Virumbrales-Muñoz, Luis J. Fernández, Iñaki Ochoa, Alodia Lacueva, Rosa Monge, M. Olave, Guillermo A. Llamazares

Publikováno v: European Journal of Cancer. 61:S91

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e342065f7d58c8d77f2273c040c75667
https://doi.org/10.1016/s0959-8049(16)61318-7

Integration of encapsulated cells on microfluidic systems for the generation and delivery of specific biomarker profiles

Autor: Gorka Orive, R.M. Hernández, Edorta Santos, Luis J. Fernández, N. Movilla, Rosa Monge, Guillermo A. Llamazares, J.L. Pedraz, Iñaki Ochoa, L. Saenz del Burgo

Publikováno v: Jornada de Jóvenes Investigadores del I3A. 1:16-18

This work presents the design and fabrication of a SU-8 based microfluidic chip for encapsulated myoblasts, a complete microfluidic setup for long term cell culture, together with the first profile secretion analysis results.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9645db3913a7e5ce15c53a4b0bed672c
https://doi.org/10.26754/jji-i3a.201401735

Mechanical and Topographical Characterization of Alginate Microcapsules

Autor: Iñaki Ochoa, Luis J. Fernández, María Virumbrales-Muñoz

Publikováno v: Jornada de Jóvenes Investigadores del I3A. 3:19-20

We used Atomic Force Microscopy (AFM) in order to characterize alginate microcapsules as for topography and stiffness. Thus, we intend to identify those which are theoretically most biocompatible by this technique, avoiding the need for animal testin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2da38733658d423971d83171f1fbda30
https://doi.org/10.26754/jji-i3a.201501642