Zobrazeno 1 - 10
of 78
pro vyhledávání: '"I/R, ischemia reperfusion"'
Autor:
Min Xu, Fang Wang, Xiaoni Kong, Junzhe Jiao, Yueqiu Gao, Xuehua Sun, Hailong Wu, Jinyang Gu, Hualian Hang, Dongwei Xu, Jichang Li, Miao Huang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 567-584 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 567-584 (2021)
Background & Aims DJ-1 is universally expressed in various tissues and organs and is involved in the physiological processes in various liver diseases. However, the role of DJ-1 in liver ischemia-reperfusion (I/R) injury is largely unknown. Methods I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a2bef2e703fa3d8ef38d5240ce768c
http://europepmc.org/articles/PMC8258983
http://europepmc.org/articles/PMC8258983
Publikováno v:
JACC: Basic to Translational Science
Highlights • Autosis is an autophagy-dependent, nonapoptotic, and non-necrotic form of cell death that is characterized by unique morphological and biochemical features, including the presence of ballooning of perinuclear space (PNS) and sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c26b11eee5dfabcba5fc42e0b5bac95
http://europepmc.org/articles/PMC7452304
http://europepmc.org/articles/PMC7452304
Publikováno v:
JACC: Basic to Translational Science
Highlights • Intravenous iron supplementation provides symptomatic relief in patients with heart failure and concomitant iron deficiency. • The current definition of iron deficiency based on ferritin
Summary To date, 3 clinical trials have s
Summary To date, 3 clinical trials have s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6416c88e304c21907d8eb5ffa905104a
https://doi.org/10.1016/j.jacbts.2019.08.009
https://doi.org/10.1016/j.jacbts.2019.08.009
Autor:
Jie Cai, Xiaoge Zhang, Peng Chen, Yang Li, Songzi Liu, Qian Liu, Hanyong Zhang, Zhuyin Wu, Ke Song, Jianmiao Liu, Bo Shan, Yong Liu
Publikováno v:
The Journal of Biological Chemistry
Hepatic ischemia/reperfusion (I/R) injury is an inflammation-mediated process arising from ischemia/reperfusion-elicited stress in multiple cell types, causing liver damage during surgical procedures and often resulting in liver failure. Endoplasmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86338028f5113cd46609ec4ba5e153f
http://europepmc.org/articles/PMC8760522
http://europepmc.org/articles/PMC8760522
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Gene therapy has been widely investigated for the treatment of genetic, acquired, and infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of causing serious adverse events, resulting in th
Gene therapy has been widely investigated for the treatment of genetic, acquired, and infectious diseases. Pioneering work utilized viral vectors; however, these are suspected of causing serious adverse events, resulting in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7413733ccbe4eda7411005d2c1ea69
http://europepmc.org/articles/PMC8518240
http://europepmc.org/articles/PMC8518240
Autor:
Pavel Montes de Oca Balderas
Publikováno v:
The Journal of Biological Chemistry
Mitochondria are known as the powerhouses of eukaryotic cells; however, they perform many other functions besides oxidative phosphorylation, including Ca2+ homeostasis, lipid metabolism, antiviral response, and apoptosis. Although other hypotheses ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0293366a3da64d47abe9c126ea3f52f0
http://europepmc.org/articles/PMC8503596
http://europepmc.org/articles/PMC8503596
Autor:
Denise Veltman, Piet Claus, Ellen Caluwé, Maarten Vanhaverbeke, Uwe Himmelreich, Stefan Janssens, Peter Pokreisz, Peter Sinnaeve, Willy Gsell, Ming Wu, Hilde Gillijns
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • The role of the CLEC4E during myocardial healing after ischemia-reperfusion injury is unknown. • CLEC4E deletion is associated with reduced cardiac injury, inflammation, and left ventricular structural and functi
Highlights • The role of the CLEC4E during myocardial healing after ischemia-reperfusion injury is unknown. • CLEC4E deletion is associated with reduced cardiac injury, inflammation, and left ventricular structural and functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a46fac4ecaf99cf50513516da72175
https://lirias.kuleuven.be/handle/123456789/680542
https://lirias.kuleuven.be/handle/123456789/680542
Autor:
Genki Horitsugi, Ryoto Sakaniwa, Hirotatsu Ohkawara, Jun Hatazawa, Shigeru Miyagawa, Yuki Mori, Yoshiki Sawa, Motoko Shiozaki, Kayako Isohashi, Shin Yajima, Satsuki Fukushima, Hiroko Iseoka, Yoshiki Sakai, Yoshichika Yoshioka, Akima Harada
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 318-331 (2019)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • Intravenously injected ONO-1301–containing nanoparticles selectively accumulated in the ischemic border area of the myocardium. • Prominent up-regulation occurred of proangiogenic cytokines such as vascular end
Highlights • Intravenously injected ONO-1301–containing nanoparticles selectively accumulated in the ischemic border area of the myocardium. • Prominent up-regulation occurred of proangiogenic cytokines such as vascular end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84059de8937d3689bee1fad0c7ca2ec
http://www.sciencedirect.com/science/article/pii/S2452302X19300063
http://www.sciencedirect.com/science/article/pii/S2452302X19300063
Autor:
Michael Böhm, Prashanthan Sanders, Dominik Linz, Thomas Hübschle, Olesja Zamyatkin, Katharina Erb, Stefan Dhein, Adrian D. Elliott, Lisa Lang, Ulrich Schotten, Mathias Hohl, Wolfgang Linz, Sven Ruf, Thorsten Sadowski
Publikováno v:
JACC: Basic to Translational Science, 4(3), 332-344. Elsevier
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 332-344 (2019)
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 3, Pp 332-344 (2019)
JACC: Basic to Translational Science
Visual Abstract
Highlights • The role of the protease cathepsin A for the progression of left ventricular remote remodeling and atrial cardiomyopathy in ischemic cardiomyopathy is unknown. • In rats with ventricular ischemia and reperfusion,
Highlights • The role of the protease cathepsin A for the progression of left ventricular remote remodeling and atrial cardiomyopathy in ischemic cardiomyopathy is unknown. • In rats with ventricular ischemia and reperfusion,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29535957f1bc344d442fdc086e514b56
https://cris.maastrichtuniversity.nl/en/publications/483210d3-9772-4df8-8365-87513e71e01e
https://cris.maastrichtuniversity.nl/en/publications/483210d3-9772-4df8-8365-87513e71e01e
Autor:
George Gardner, Evangelia G. Kranias, Guo-Chang Fan, Guan-Sheng Liu, Jiang Qian, Yutian Li, Nathan Robbins, Kobra Haghighi, Jack Rubinstein, Burns C. Blaxall, Min Jiang, Joshua G. Travers
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • PKA-phosphorylation of Hsp20 is elevated in human failing hearts. • Increases in phosphorylated Hsp20 in vivo are associated with fibrotic remodeling and reduced left ventricular function. • The phosphorylated
Highlights • PKA-phosphorylation of Hsp20 is elevated in human failing hearts. • Increases in phosphorylated Hsp20 in vivo are associated with fibrotic remodeling and reduced left ventricular function. • The phosphorylated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26181058fcf099bc40c4dd72e341bce2
http://europepmc.org/articles/PMC6488766
http://europepmc.org/articles/PMC6488766