Zobrazeno 1 - 10
of 342
pro vyhledávání: '"I, van Wijngaarden"'
Autor:
Richard A. Glennon
Publikováno v:
Journal of Medicinal Chemistry. 41:3917-3918
Autor:
Glennon, R. A.
Publikováno v:
Journal of Medicinal Chemistry; September 24, 1998, Vol. 41 Issue: 20 p3917-3918, 2p
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 112:126-130
Medicinal chemists have provided crucial tools for the identification and characterization of various subtypes of serotonin (5-hydroxytryptamine, 5-HT) receptors. At present, potent and selective (ratio ≥ 100) ligands have been developed for the 5-
Autor:
Sharma A; Natural Products & Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, 180001, India.; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, 201002, India., Sharma M; Natural Products & Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, 180001, India.; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, 201002, India., Bharate SB; Natural Products & Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, 180001, India.; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, 201002, India.; Department of Natural Products & Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, 500007, India.
Publikováno v:
ChemMedChem [ChemMedChem] 2024 Oct 16; Vol. 19 (20), pp. e202400384. Date of Electronic Publication: 2024 Aug 23.
Autor:
I van Wijngaarden, W. Soudijn
Publikováno v:
Current Medicinal Chemistry. 7:1063-1079
GABA is the major inhibitory neurotransmitter in the brain and GABA re- uptake from the synaptic cleft is one important mechanism in the regulation of GABA activity. Inhibition of the re-uptake of GABA by potent and selective inhibitors of the GABA t
Publikováno v:
ChemInform. 22
On the basis of a model we recently developed for the antagonist binding site of the adenosine A1 receptor (J. Med. Chem. 1990, 33, 1708-1713), it was predicted that 1H-imidazo[4,5-c]quinolin-4-amines would be antagonists of the A1 receptor. Furtherm
Publikováno v:
ChemInform. 24
Medicinal chemists have provided crucial tools for the identification and characterization of various subtypes of serotonin (5-hydroxytryptamine, 5-HT) receptors. At present, potent and selective (ratio ≥ 100) ligands have been developed for the 5-
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 30
Autor:
W. Soudijn, P. Nissen, I. Van Wijngaarden, Th. H. W. Van Vlijmen, P. J. M. Van Galen, A. P. Ljzerman
Publikováno v:
Nucleosides and Nucleotides. 10:1039-1047
With the aid of molecular modelling both adenosine and adenosine A, receptor antagonists belonging to various chemical classes were compared. A model for the antagonist binding site was developed. As a consequence 1H-imidazo[4, 5-c]-quinolin-4-amines