Zobrazeno 1 - 10
of 559
pro vyhledávání: '"I, Ziegler"'
Autor:
Artem Zatcepin, Johannes Gnörich, Boris-Stephan Rauchmann, Laura M. Bartos, Stephan Wagner, Nicolai Franzmeier, Maura Malpetti, Xianyuan Xiang, Yuan Shi, Samira Parhizkar, Maximilian Grosch, Karin Wind-Mark, Sebastian T. Kunte, Leonie Beyer, Carolin Meyer, Desirée Brösamle, Ann-Christin Wendeln, Collins Osei-Sarpong, Steffanie Heindl, Arthur Liesz, Sophia Stoecklein, Gloria Biechele, Anika Finze, Florian Eckenweber, Simon Lindner, Axel Rominger, Peter Bartenstein, Michael Willem, Sabina Tahirovic, Jochen Herms, Katharina Buerger, Mikael Simons, Christian Haass, Rainer Rupprecht, Markus J. Riemenschneider, Nathalie L. Albert, Marc Beyer, Jonas J. Neher, Lars Paeger, Johannes Levin, Günter U. Höglinger, Robert Perneczky, Sibylle I. Ziegler, Matthias Brendel
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-25 (2024)
Abstract Background Microglial activation is one hallmark of Alzheimer disease (AD) neuropathology but the impact of the regional interplay of microglia cells in the brain is poorly understood. We hypothesized that microglial activation is regionally
Externí odkaz:
https://doaj.org/article/a5bbc5a0c7914c46ad9ff511752e6937
Autor:
Artem Zatcepin, Anna Kopczak, Adrien Holzgreve, Sandra Hein, Andreas Schindler, Marco Duering, Lena Kaiser, Simon Lindner, Martin Schidlowski, Peter Bartenstein, Nathalie Albert, Matthias Brendel, Sibylle I. Ziegler
Publikováno v:
Zeitschrift für Medizinische Physik, Vol 34, Iss 2, Pp 218-230 (2024)
Introduction: Neuroinflammation evaluation after acute ischemic stroke is a promising option for selecting an appropriate post-stroke treatment strategy. To assess neuroinflammation in vivo, translocator protein PET (TSPO PET) can be used. However, t
Externí odkaz:
https://doaj.org/article/99ad1382f4344a14b663f0a534b4d97d
Autor:
Mikhail Rumiantcev, Wei Bo Li, Simon Lindner, Grigory Liubchenko, Sandra Resch, Peter Bartenstein, Sibylle I. Ziegler, Guido Böning, Astrid Delker
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-22 (2023)
Abstract Aim Over recent years, [225Ac]Ac-PSMA and [177Lu]Lu-PSMA radiopharmaceutical therapy have evolved as a promising treatment option for advanced prostate cancer. Especially for alpha particle emitter treatments, there is still a need for impro
Externí odkaz:
https://doaj.org/article/442d4e0d597649b28d88dfdb5d887711
Autor:
Anna Ballweg, Carolin Klaus, Letizia Vogler, Sabrina Katzdobler, Karin Wind, Artem Zatcepin, Sibylle I. Ziegler, Birkan Secgin, Florian Eckenweber, Bernd Bohr, Alexander Bernhardt, Urban Fietzek, Boris-Stephan Rauchmann, Sophia Stoecklein, Stefanie Quach, Leonie Beyer, Maximilian Scheifele, Marcel Simmet, Emanuel Joseph, Simon Lindner, Isabella Berg, Norman Koglin, Andre Mueller, Andrew W. Stephens, Peter Bartenstein, Joerg C. Tonn, Nathalie L. Albert, Tania Kümpfel, Martin Kerschensteiner, Robert Perneczky, Johannes Levin, Lars Paeger, Jochen Herms, Matthias Brendel
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Objectives Reactive gliosis is a common pathological hallmark of CNS pathology resulting from neurodegeneration and neuroinflammation. In this study we investigate the capability of a novel monoamine oxidase B (MAO-B) PET ligand to monitor r
Externí odkaz:
https://doaj.org/article/497126e6fe484a14b58f292c7979ad26
Autor:
Artem Zatcepin, Sibylle I. Ziegler
Publikováno v:
Zeitschrift für Medizinische Physik, Vol 33, Iss 1, Pp 4-12 (2023)
Positron emission tomography is a highly sensitive molecular imaging modality, based on the coincident detection of annihilation photons after positron decay. The most used detector is based on dense, fast, and luminous scintillators read out by ligh
Externí odkaz:
https://doaj.org/article/40e1a38e6a3047e18719fd472298bba0
Autor:
Sandra Resch, Sarah Takayama Fouladgar, Mathias Zacherl, Gabriel T. Sheikh, Grigory Liubchenko, Mikhail Rumiantcev, Lena M. Unterrainer, Vera Wenter, Peter Bartenstein, Sibylle I. Ziegler, Harun Ilhan, Leonie Beyer, Guido Böning, Astrid Delker
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-16 (2023)
Abstract Background 177Lu-PSMA therapy has been successfully used to prolong the survival of patients with metastatic castration-resistant prostate cancer. Patient-specific dosimetry based on serial quantitative SPECT/CT imaging can support the under
Externí odkaz:
https://doaj.org/article/2ce067d4e88d47b7b2920f87feaee6ca
Autor:
Julia Dubowitz, Alexandra I Ziegler, Richard Beare, Fabian Jost-Brinkmann, Adam K Walker, Ryan D Gillis, Aeson Chang, Ni-Chun Chung, Olga A Martin, Frédéric Hollande, Bernhard Riedel, Erica K Sloan
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293905 (2023)
BackgroundSurgery is essential for curative treatment of solid tumors. Evidence from recent retrospective clinical analyses suggests that use of propofol-based total intravenous anesthesia during cancer resection surgery is associated with improved o
Externí odkaz:
https://doaj.org/article/3847f45936474b739852fce36cd2452a
Autor:
Letizia Vogler, Anna Ballweg, Bernd Bohr, Nils Briel, Karin Wind, Melissa Antons, Lea H. Kunze, Johannes Gnörich, Simon Lindner, Franz-Josef Gildehaus, Karlheinz Baumann, Peter Bartenstein, Guido Boening, Sibylle I. Ziegler, Johannes Levin, Andreas Zwergal, Günter U. Höglinger, Jochen Herms, Matthias Brendel
Publikováno v:
NeuroImage: Clinical, Vol 39, Iss , Pp 103484- (2023)
Objective: In preclinical research, the use of [18F]Fluorodesoxyglucose (FDG) as a biomarker for neurodegeneration may induce bias due to enhanced glucose uptake by immune cells. In this study, we sought to investigate synaptic vesicle glycoprotein 2
Externí odkaz:
https://doaj.org/article/e04b066b10e24880aff8602e5be0aa58
Autor:
Adam J. Lawther, Andrew J.K. Phillips, Ni-Chun Chung, Aeson Chang, Alexandra I. Ziegler, Sophie Debs, Erica K. Sloan, Adam K. Walker
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 21, Iss , Pp 100428- (2022)
Disruption of circadian rhythms occurs in rotating shift-work, jetlag, and in individuals with irregular sleep schedules. Circadian disruption is known to alter inflammatory responses and impair immune function. However, there is limited understandin
Externí odkaz:
https://doaj.org/article/893f8defe3da459eadfa31e0841bfb45
Autor:
Artem Zatcepin, Steffanie Heindl, Ulrike Schillinger, Lena Kaiser, Simon Lindner, Peter Bartenstein, Anna Kopczak, Arthur Liesz, Matthias Brendel, Sibylle I. Ziegler
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
AimUnderstanding neuroinflammation after acute ischemic stroke is a crucial step on the way to an individualized post-stroke treatment. Microglia activation, an essential part of neuroinflammation, can be assessed using [18F]GE-180 18 kDa translocato
Externí odkaz:
https://doaj.org/article/a90e770084e64272b9591d18a67c6d99