Zobrazeno 1 - 10
of 89
pro vyhledávání: '"I, Vrhovec"'
Publikováno v:
The International Journal of Biological Markers. 18:106-115
The present study on the prognostic and predictive value of serine proteases was conducted in 460 early breast cancer patients mostly treated with some kind of adjuvant systemic therapy: 156 received chemotherapy, 141 hormone therapy and 111 a combin
Publikováno v:
The International Journal of Biological Markers. 17:33-41
The independent prognostic value of protease uPA and its inhibitor PAI-1 for survival in breast cancer patients is firmly established. However, there is very little data on the prognostic value of serine proteases and their inhibitors for locoregiona
Publikováno v:
Neoplasma. 52(1)
None of the established prognostic factors in breast cancer (BC) is able to determine the final outcome with certainity. Tumor biological factors involved in tumor invasion and metastasis, such as cathepsins and proteins of u-PA system, have been put
Publikováno v:
The International journal of biological markers. 17(2)
The prognosis of cancer is primarily dependent on its potential to invade and metastasize. Data from both pre-clinical and clinical studies strongly suggest that serine proteases, as well as their inhibitors and receptor, play a central role in the p
Autor:
M, Sprem, D, Babić, M, Abramić, I, Vrhovec, J, Skrk, D, Milicić, A, Ambriović Ristov, D, Kalafatić, M, Osmak
Publikováno v:
Croatian medical journal. 42(6)
To determine the activity of glutathione (GSH) and concentrations of glutathione S-transferases (GST), urokinase type plasminogen activator (uPA), and plasminogen activator inhibitor type 1 (PAI-1), and to evaluate their diagnostic and prognostic val
Publikováno v:
Neoplasma. 48(1)
Cysteine proteinases cathepsin (Cath) B and L and their endogenous inhibitors stefin (Stef) A and B concentrations were measured using a quantitative immunosorbent assay (ELISA; KRKA d.d., Novo mesto, Slovenia) in serum samples from 35 patients with
Publikováno v:
Anticancer research. 20(5C)
The aim of the study was to evaluate the prognostic significance of tumour and serum concentrations of urokinase-type plasminogen activator (uPA), its type 1 inhibitor (PAI-1) and cathepsin D (Cath D) in patients with squamous cell carcinoma of the h
Publikováno v:
Anticancer research. 19(4B)
The association between drug-resistance and three markers for invasive capacity: cathepsin D (Cath D), urokinase type plasminogen activator (uPA) and inhibitor of plasminogen activator type 1 (PAI-1) was examined in nine cervical and laryngeal carcin
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(10)
The levels of cathepsins (Cats) B, H, and L and their inhibitors stefin A and cystatin C were determined in the sera of 43 patients with metastatic melanoma, in 54 patients with treated cutaneous melanoma with no evidence of metastatic disease, and i
Publikováno v:
Neoplasma. 44(3)
Doxorubicin shows a wide spectrum of activities in solid tumors, especially against breast carcinoma. The aim of this study was to examine if doxorubicin, when given at lower concentrations than applied in clinic, may induce changes in treated cells.