Zobrazeno 1 - 10
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pro vyhledávání: '"I, McFadzean"'
Akademický článek
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Publikováno v:
Trends in Pharmacological Sciences. 19:266-269
In many non-excitable cells, activation of phospholipase C-linked receptors results in a biphasic increase in the cytosolic Ca2+ concentration; an initial transient increase, owing to the release of Ca2+ from the endoplasmic/sarcoplasmic reticulum (E
Publikováno v:
British journal of pharmacology. 132(4)
1. The object of this study was to determine whether inhibition of capacitative calcium entry is essential for relaxation of the mouse anococcygeus via the NO/cyclic GMP signalling pathway. 2. In intact muscles, thapsigargin (Tg; 100 nM)-induced tone
Publikováno v:
Trends in pharmacological sciences. 19(7)
In many non-excitable cells, activation of phospholipase C-linked receptors results in a biphasic increase in the cytosolic Ca2+ concentration; an initial transient increase, owing to the release of Ca2+ from the endoplasmic/sarcoplasmic reticulum (E
Akademický článek
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Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 329(1)
Nonadrenergic noncholinergic (NANC) relaxations of the anococcygeus muscle are reduced by inhibitors of nitric oxide synthase (NOS). Since NOS can be detected within 6-hydroxydodpamine-resistant nerve tracts running through the muscle, it seems clear
Publikováno v:
Methods in enzymology. 238
Autor:
S England, I McFadzean
Publikováno v:
Pflugers Archiv : European journal of physiology. 421(2-3)
The properties of the voltage- and time-dependent outward current in single smooth muscle cells isolated from the rat anococcygeus were studied. The outward current was activated by depolarizations to membrane potentials positive to -40 mV. Activatio
Publikováno v:
Agents and actions. Supplements. 38
Under whole-cell recording, bradykinin (BK) produced an initial outward membrane current followed by an inward current in voltage-clamped NG108-15 cells. The initial outward current was associated with a rise in intracellular Ca2+ and was accompanied