PO-276 Histone acetylation readers BET in hypoxia adaptation in triple negative breast cancer (TNBC)

Autor: Alan McIntyre, Dilair Baban, M A De Bastiani, I. Ledaki, D. Heery, K. Stefan, Leonardo Lisbôa da Motta, Shozeb Haider, Fábio Klamt, A L Harris

Publikováno v: ESMO Open. 3:A335

Introduction Hypoxia (low oxygen) is associated with worst prognosis and therapy resistance in most solid tumours. Hypoxia occurs in ~50% of breast cancer, most frequently in triple negative breast cancer (TNBC), the most aggressive subtype. Hypoxia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29208b0844507b795b49b00c0f2edb54
https://doi.org/10.1136/esmoopen-2018-eacr25.790

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The Lipid Droplet Protein DHRS3 Is a Regulator of Melanoma Cell State.

Autor: Johns E; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Ma Y; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, New York, USA., Louphrasitthiphol P; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK., Peralta C; The Proteomics Resource Center at the Rockefeller University, New York, New York, USA., Hunter MV; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Raymond JH; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK., Molina H; The Proteomics Resource Center at the Rockefeller University, New York, New York, USA., Goding CR; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK., White RM; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK.

Publikováno v: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2024 Oct 31. Date of Electronic Publication: 2024 Oct 31.

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