Zobrazeno 1 - 10
of 927
pro vyhledávání: '"I, JENSEN"'
Autor:
Sophie B. Jensen, Ditte E. Jæhger, Elizabeth Serrano-Chávez, Hólmfríður R. Halldórsdóttir, Trine B. Engel, Jennifer S. Jørgensen, Unnur J. Björgvinsdóttir, Serhii Kostrikov, Marouschka J. Scheeper, Lars Ringgaard, Linda M. Bruun, Camilla Stavnsbjerg, Esben Christensen, Martin Bak, Julianna Thuroczy, Lajos Balogh, Andreas T. I. Jensen, Fredrik Melander, Andreas Kjaer, Jonas R. Henriksen, Anders E. Hansen, Thomas L. Andresen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cancer curing immune responses against heterogeneous solid cancers require that a coordinated immune activation is initiated in the antigen avid but immunosuppressive tumor microenvironment (TME). The plastic TME, and the poor systemic toler
Externí odkaz:
https://doaj.org/article/d50340662d0947fe879e809163698218
Autor:
A. Nascimento Osorio, R. Sánchez de la Rosa, A. Roca, J. Montaner Picart, I. Jensen, B. Miller, T. Haselkorn, F. Solomon
Publikováno v:
Neurology Perspectives, Vol 4, Iss , Pp 243- (2024)
Externí odkaz:
https://doaj.org/article/fba9d4b9231c4d50afeeb63b494299f0
Autor:
Demi van der Horst, Naziia Kurmasheva, Mikkel H. S. Marqvorsen, Sonia Assil, Anna H. F. Rahimic, Christoph F. Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B. Iversen, Fanghui Ren, Trine I. Jensen, Ryo Narita, Vivien R. Schack, Bao-cun Zhang, Rasmus O. Bak, Claudio Sette, Robert A. Fenton, Jacob G. Mikkelsen, Søren R. Paludan, David Olagnier
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract DNA is a danger signal sensed by cGAS to engage signaling through STING to activate innate immune functions. The best-studied downstream responses to STING activation include expression of type I interferon and inflammatory genes, but STING
Externí odkaz:
https://doaj.org/article/0db80e2a99374afa9c136a61eb6b74e2
Autor:
Nanna S. Mikkelsen, Sabina S. Hernandez, Trine I. Jensen, Jessica L. Schneller, Rasmus O. Bak
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 1-16 (2023)
CRISPR-Cas-mediated site-specific integration of transgenes by homology-directed repair (HDR) is challenging, especially in primary cells, where inferior editing efficiency may impede the development of gene- and cellular therapies. Various strategie
Externí odkaz:
https://doaj.org/article/f2b78d2a32624f20b177aadcf3362a66
Autor:
Ditte Jaehger, Iulia Diaconu, Anders Laustsen, Tobias W Bjerg, Aida S Hansen, Trine I Jensen, Mette-Louise Trempenau, Kasper M Jensen, Nicolai O Haahr, Marcus N Rosendal, Jonas B Vejlebo, Rasmus O Bak, Martin R Jakobsen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/be21790330ad40b3a927b263360bf8a2
Publikováno v:
Palliative Medicine Reports, Vol 3, Iss 1, Pp 296-307 (2022)
Background: Conducting a conversation about wishes for treatment at end of life (EOL) has been shown to improve EOL care for patients and relatives. Still, only a minority of physicians conduct the conversation, which might lead to unwanted intervent
Externí odkaz:
https://doaj.org/article/8e256e5c8483487cb6bb6599845b858f
Autor:
Jasper L.S.P. Driessen, Josefin Johnsen, Ivan Pogrebnyakov, Elsayed T.T. Mohamed, Solange I. Mussatto, Adam M. Feist, Sheila I. Jensen, Alex T. Nielsen
Publikováno v:
Metabolic Engineering Communications, Vol 16, Iss , Pp e00223- (2023)
Microbial tolerance to toxic compounds formed during biomass pretreatment is a significant challenge to produce bio-based products from lignocellulose cost effectively. Rational engineering can be problematic due to insufficient prerequisite knowledg
Externí odkaz:
https://doaj.org/article/d9dacf8e27544532aac2078f90d669d9
Autor:
G. W. Severin, J. Fonslet, L. K. Kristensen, C. H. Nielsen, A. I. Jensen, A. Kjær, A. P. Mazar, K. Johnston, U. Köster
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The in vivo-generator radionuclides 140Nd (t1/2 = 3.4 d) and 134Ce (t1/2 = 3.2 d) were used to trace a urokinase-type plasminogen activator (uPA)-targeting mouse monoclonal antibody, ATN-291, in U87 MG xenograft tumor-bearing mice. ATN-291 i
Externí odkaz:
https://doaj.org/article/e503e6376d564bf78ef992a7be8638fe
Autor:
Emanuel Sporer, Christian B. M. Poulie, Sture Lindegren, Emma Aneheim, Holger Jensen, Tom Bäck, Paul J. Kempen, Andreas Kjaer, Matthias M. Herth, Andreas I. Jensen
Publikováno v:
Journal of Nanotheranostics, Vol 2, Iss 4, Pp 196-207 (2021)
Targeted α-therapy (TAT) can eradicate tumor metastases while limiting overall toxicity. One of the most promising α-particle emitters is astatine-211 (211At). However, 211At-carbon bonds are notoriously unstable in vivo and no chelators are availa
Externí odkaz:
https://doaj.org/article/fc6d21baaf7241e9801fd9856d9fa10c
Autor:
Daren C. Card, Andrew G. Van Camp, Trenten Santonastaso, Michael I. Jensen-Seaman, Nicola M. Anthony, Scott V. Edwards
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The major histocompatibility complex (MHC) is an important genomic region for adaptive immunity and has long been studied in ecological and evolutionary contexts, such as disease resistance and mate and kin selection. The MHC has been investigated ex
Externí odkaz:
https://doaj.org/article/85c3af5115094e9fabfba1bb196fb451