Zobrazeno 1 - 10
of 246
pro vyhledávání: '"I, Hanbauer"'
Autor:
John A. Cook, Murali Krishna, I. Hanbauer, David A. Wink, William DeGraff, Janet Gamson, James B. Mitchell
Publikováno v:
Archives of Biochemistry and Biophysics. 319:402-407
Endogenously formed nitric oxide (NO) possesses diverse properties such as regulating physiological functions, exerting specific toxic effects, and protecting against various toxic substances. Recent studies suggest that in the presence of reactive o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26390e288391bd89817d85077a6c9f10
https://doi.org/10.1006/abbi.1995.1310
https://doi.org/10.1006/abbi.1995.1310
Autor:
D A, Wink, R W, Nims, J F, Darbyshire, D, Christodoulou, I, Hanbauer, G W, Cox, F, Laval, J, Laval, J A, Cook, M C, Krishna
Publikováno v:
Chemical Research in Toxicology. 7:519-525
The critical regulatory function of nitric oxide (NO) in many physiologic processes is well established. However, in an aerobic aqueous environment NO is known to generate one or more reactive and potentially toxic nitrogen oxide (NOx) metabolites. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3e8aa862a67ce37456436a1fc1cf56
https://doi.org/10.1021/tx00040a007
https://doi.org/10.1021/tx00040a007
Publikováno v:
Restorative neurology and neuroscience. 12(2-3)
In the trisomy 16 mouse the increased gene dosage of SOD-1 increases H2O2 production that results in increased oxidative stress. We report here that in hippocampal primary cultures, metallothionein (MT)-I/II immunoreactivity was present mainly in gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6966a088b1a96ed56d44d6832b6fe524
https://pubmed.ncbi.nlm.nih.gov/12671302
https://pubmed.ncbi.nlm.nih.gov/12671302
Publikováno v:
Restorative neurology and neuroscience. 12(2-3)
E14 mesencephalic cultures grown 6 days in Neurobasal Medium containing 10% horse serum consist of differentiated neurons and astroglia. In these cultures, glutathione and metallothionein-I/II are enriched in astrocytes and play an important role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::983e070c8a15299ea7c77cfc35906414
https://pubmed.ncbi.nlm.nih.gov/12671303
https://pubmed.ncbi.nlm.nih.gov/12671303
Autor:
M, Scortegagna, I, Hanbauer
Publikováno v:
Neurochemical research. 25(6)
Pb was shown to perturb neuronal and glial function either directly by interacting with protein thiol groups or indirectly by mimicking Ca(2+) and increasing oxidative stress. In view of the potential action of Pb on cellular redox homeostasis we stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a89c7c4aaf7dcbf2bfcc5ad74f27b4b7
https://pubmed.ncbi.nlm.nih.gov/10944005
https://pubmed.ncbi.nlm.nih.gov/10944005
Publikováno v:
Journal of chemical neuroanatomy. 14(3-4)
We investigated the effects of nitric oxide on an in vitro and in vivo generation of hydroxyl radicals, and in vivo neurotoxicity caused by intranigral infusion of ferrous citrate in rats. The formation of hydroxyl radicals in vitro, without exogenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d0bdef0f53a2f5ccf27795cf36973a
https://pubmed.ncbi.nlm.nih.gov/9704898
https://pubmed.ncbi.nlm.nih.gov/9704898
Autor:
M, Scortegagna, I, Hanbauer
Publikováno v:
Neurotoxicology. 18(2)
The effect of Pb2+ was studied in embryonic mesencephalic primary cultures that contain neurons and glia. Pb2+ exposure in absence of serum, damaged more efficaciously the cultured cells than Pb2+ exposure in presence of serum. In serum-free medium,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ad31d7316c7aff759ea921928670009
https://pubmed.ncbi.nlm.nih.gov/9291483
https://pubmed.ncbi.nlm.nih.gov/9291483
Publikováno v:
Pharmacological reviews. 46(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c8f94ace387be83f5818baa8e52c1a6
https://pubmed.ncbi.nlm.nih.gov/7899474
https://pubmed.ncbi.nlm.nih.gov/7899474
Publikováno v:
Life Sciences. 14:1169-1188
Publisher Summary This chapter discusses the role of cyclic nucleotides in promoting the trans-synaptic induction of tyrosine hydroxylase. An increase of activity at synapses impinging on either sympathetic ganglia or adrenal chromaffin cells results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630b1b818a3d611d38f45da0bd552cb4
https://doi.org/10.1016/0024-3205(74)90425-1
https://doi.org/10.1016/0024-3205(74)90425-1
Autor:
S Hellstrom, I Hanbauer
Publikováno v:
The Journal of Physiology. 282:21-34
1. The mechanism whereby hypoxia lasting 20 min elicits a decrease in the dopamine content of rat carotid bodies was studied. 2. The concentrations of dopamine, noradrenaline, dihydroxyphenylacetic acid and homovanillic acid in carotid body were meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c188af2956ffde902d4c5bb3d42932
https://doi.org/10.1113/jphysiol.1978.sp012445
https://doi.org/10.1113/jphysiol.1978.sp012445