Zobrazeno 1 - 10
of 53
pro vyhledávání: '"I, Grynyuk"'
Autor:
S. V. Prylutska, I. I. Grynyuk, T. D. Skaterna, L. B. Drobot, N. S. Slobodyanik, O. P. Matyshevska
Publikováno v:
Biotechnologia Acta, Vol 13, Iss 3, Pp 45-51 (2020)
The aim of this study was to evaluate the toxicity of noncovalent nanocomplex of C60 fullerene with cisplatin (C60-Cis-Pt) against normal cells. The toxicity of the C60-Cis-Pt nanocomplex compared to the free Cis-Pt was studied by estimating kidney
Externí odkaz:
https://doaj.org/article/d143e62542754433bdf626a5f8347d61
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 3, Pp 41-48 (2018)
Ca2+-regulating system in cancer cells is suggested to be remodulated particularly by reduced store-operated Ca2+ entry (SOCE) through plasma membrane in order to maintain moderately reduced cytosolic Ca2+ concentration and to avoid apoptosis. The en
Externí odkaz:
https://doaj.org/article/193cde9fed544d04b694d3deda94fc21
Autor:
A. Grebinyk, S. Prylutska, I. Grynyuk, B. Kolp, V. Hurmach, T. Sliva, V. Amirkhanov, V. Trush, O. Matyshevska, M. Slobodyanik, Yu. Prylutskyy, M. Frohme, U. Ritter
Publikováno v:
Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract New representative of carbacylamidophosphates - diphenyl-N-(trichloroacetyl)-amidophosphate (HL), which contains two phenoxy substituents near the phosphoryl group, was synthesized, identified by elemental analysis and IR and NMR spectroscop
Externí odkaz:
https://doaj.org/article/998639c7606d4713a6dea07b04974eb2
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 1, Pp 44-50 (2016)
The early response of normal (Wistar rat thymocytes) and transformed (mice lymphoid leukemia L1210) cells to treatment with anticancer drug cisplatin or to combined treatment with cisplatin and carbon nanostructure fullerene C60 was studied. We demon
Externí odkaz:
https://doaj.org/article/36f72aedca024bd2a45c3409387aa7f1
Autor:
N. Yu. Strutynska, I. I. Grynyuk, O. M. Vasyliuk, S. V. Prylutska, L. L. Vovchenko, I. A. Kraievska, N. S. Slobodyanik, U. Ritter, Yu. I. Prylutskyy
Publikováno v:
Arabian Journal for Science and Engineering. 47:7093-7104
Autor:
I. I. Grynyuk, S. V. Prylutska, N. S. Kariaka, T. Yu. Sliva, O. V. Moroz, D. V. Franskevych, V. M. Amirkhanov, O. P. Matyshevska, M. S. Slobodyanik
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 6, Pp 154-161 (2015)
Structural analogues of β-diketones – dimethyl-N-(benzoyl)amidophosphate (HCP) and dimethyl-N-(phenylsulfonyl)amidophosphate (HSP) were synthesized and identified by the methods of IR, 1H and 31P NMR spectroscopy. Screening of biological activity
Externí odkaz:
https://doaj.org/article/c8893b79ded9401391129e60e3ff8b15
Autor:
Borys V. Zakharchenko, Ilona V. Raspertova, Anna Grebinyk, Dmytro M. Khomenko, M.S. Slobodyanik, Sergiu Shova, Marcus Frohme, Svitlana Prylutska, Roman O. Doroschuk, O. P. Matyshevska, I. I. Grynyuk, Rostislav D. Lampeka
Publikováno v:
Chemical Papers. 75:4899-4906
The structure of complex cis-Pd(HLMe)Cl2 was studied both in solution and in solid state using multinuclear (1H, 13C, 15N) NMR spectroscopy and X-ray structural analysis. Complex was evaluated for cytotoxic activity. Thus, the results showed that cis
Autor:
I. I. Grynyuk, M.S. Slobodyanik, Svitlana Prylutska, Nataliia Strutynska, Vasyliuk Om, Oksana V. Livitska
Publikováno v:
Open Chemistry, Vol 19, Iss 1, Pp 39-48 (2021)
Nanoparticles (25–50 nm) of chemically modified calcium phosphates Ca10−x−y M ii x Na y (PO4)6−z (CO3) z (OH)2 (M ii – Cu2+, Zn2+) were synthesized via a wet precipitation method at room temperature. The Fourier-transform infrared spectrosc
Autor:
I. I. Grynyuk, Svitlana Prylutska, O. P. Matyshevska, Ganna Pasichnyk, Franskevych Dv, Liudmyla Drobot, Uwe Ritter
Publikováno v:
BioImpacts, Vol 9, Iss 4, Pp 211-217 (2019)
Introduction: C60 fullerene has received great attention as a candidate for biomedical applications. Due to unique structure and properties, C60 fullerene nanoparticles are supposed to be useful in drug delivery, photodynamic therapy (PDT) of cancer,
Autor:
A.G. Naumovets, Uwe Ritter, I. I. Grynyuk, Anna Grebinyk, T. D. Skaterna, Marcus Frohme, A. Senenko, Svitlana Prylutska, O. P. Matyshevska, Iryna Horak, Liudmyla Drobot, Yuriy Prylutskyy
Publikováno v:
Archives of Toxicology. 93:1213-1226
Cisplatin (Cis-Pt) is the cytotoxic agent widely used against tumors of various origin, but its therapeutic efficiency is substantially limited by a non-selective effect and high toxicity. Conjugation of Cis-Pt with nanocarriers is thought to be one