Zobrazeno 1 - 10
of 303
pro vyhledávání: '"I, Goldschneider"'
Publikováno v:
The Journal of Immunology. 158:2150-2155
Recent reports have suggested that the dichotomy between central (thymic) and peripheral T cell tolerance is not absolute and that self-tolerance in perinatal animals may also involve the intrathymic generation and release to the periphery of Ag-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19b7b1ed29c7d4f8cc76538fe56bf6ab
https://doi.org/10.4049/jimmunol.158.5.2150
https://doi.org/10.4049/jimmunol.158.5.2150
Autor:
H Hosseinzadeh, I Goldschneider
Publikováno v:
The Journal of Immunology. 150:1670-1679
Studies of the functional properties and developmental potentials of immediate post-thymic cells have been hampered by the lack of reliable markers with which to distinguish recent thymic emigrants (RTE) from the bulk of peripheral T cells. In the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66bf297f758e7d2c289336c2d364cfc5
https://doi.org/10.4049/jimmunol.150.5.1670
https://doi.org/10.4049/jimmunol.150.5.1670
Autor:
E Donskoy, I Goldschneider
Publikováno v:
The Journal of Immunology. 148:1604-1612
This study was designed to resolve the long standing controversy as to whether hematogenous precursors or resident intrathymic precursors maintain thymocytopoiesis in postnatal life. The kinetics of thymic chimerism was examined over a 21-wk period i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::694344e8bbd74cc5da720c8851bca81d
https://doi.org/10.4049/jimmunol.148.6.1604
https://doi.org/10.4049/jimmunol.148.6.1604
Publikováno v:
Journal of leukocyte biology. 69(5)
Injection of antigen into the anterior chamber (AC) of the eye, an immunologically privileged site, is associated with the induction of immune deviation, as evidenced by T helper cell (Th) 1 to Th2 cell polarization. We recently demonstrated that AC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8284404f08489a01b9945d787734031
https://pubmed.ncbi.nlm.nih.gov/11358982
https://pubmed.ncbi.nlm.nih.gov/11358982
Autor:
D Y, Wu, I, Goldschneider
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(11)
Cyclosporin A (CSA)-induced autologous graft-vs-host disease (autoGVHD) is an autoimmune syndrome initiated by autoeffector T cells presumed to be exported from the thymus during CSA treatment. The appearance of noncytotoxic immunoregulatory T cell a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c444724954acae0fa1c0696a98c0442
https://pubmed.ncbi.nlm.nih.gov/10352315
https://pubmed.ncbi.nlm.nih.gov/10352315
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(12)
Diabetes-prone (DP) BioBreeding (BB) rats develop spontaneous autoimmune diabetes. DP-BB thymocyte export is reduced, and most thymic emigrants disappear rapidly from peripheral lymphoid tissues. DP-BB rats are consequently lymphopenic and circulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72e2795f426c3be803598a58a7775467
https://pubmed.ncbi.nlm.nih.gov/9637495
https://pubmed.ncbi.nlm.nih.gov/9637495
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(5)
Evidence is provided in a companion paper for an IL-7-associated molecular complex that selectively stimulates the proliferation and presumptive differentiation of pre-pro-B cells in our long-term bone marrow culture system and "primes" them to proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5059fc437dcc745530ab13f59feb851
https://pubmed.ncbi.nlm.nih.gov/9498768
https://pubmed.ncbi.nlm.nih.gov/9498768
Publikováno v:
Autoimmunity. 24(1)
Abnormalities in postthymic T cell development in the BB/W rat model of autoimmune insulin-dependent diabetes mellitus (IDDM) result in part from a lymphopenia (lyp) gene defect. To better characterize these abnormalities, the phenotypes of T cells f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fdf870e86a50a0c82fef47deb6c9a1e8
https://pubmed.ncbi.nlm.nih.gov/8937686
https://pubmed.ncbi.nlm.nih.gov/8937686
Publikováno v:
Experimental hematology. 22(12)
In a selective culture system, the in vitro generation of terminal deoxynucleotidyl transferase positive (TdT+) B cell progenitors from rat, mouse, and human bone marrow (BM) is characterized by initial lymphoid colonization of a mouse BM feeder laye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7947d7a14f9d7cab93202ea044bdffb0
https://pubmed.ncbi.nlm.nih.gov/7925780
https://pubmed.ncbi.nlm.nih.gov/7925780
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 69(5)
We have previously demonstrated the feasibility of generating terminal deoxynucleotidyl transferase-positive (TdT+) lymphoid precursor cells in vitro in the nonadherent compartment of a long-term xenogeneic culture system in which rat bone marrow (BM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6322950533435d3b11094d279bbfb1b2
https://pubmed.ncbi.nlm.nih.gov/8246452
https://pubmed.ncbi.nlm.nih.gov/8246452