Zobrazeno 1 - 10
of 89
pro vyhledávání: '"I, Frederick"'
Autor:
Samuel S. Slattery, Daniel J. Giguere, Emily E. Stuckless, Arina Shrestha, Lee-Ann K. Briere, Alexa Galbraith, Stephen Reaume, Xenia Boyko, Henry H. Say, Tyler S. Browne, Mallory I. Frederick, Jeremy T. Lant, Ilka U. Heinemann, Patrick O’Donoghue, Liann Dsouza, Steven Martin, Peter Howard, Christopher Jedeszko, Kinza Ali, Garth Styba, Martin Flatley, Bogumil J. Karas, Gregory B. Gloor, David R. Edgell
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The worldwide COVID-19 pandemic caused by the SARS-CoV-2 betacoronavirus has highlighted the need for a synthetic biology approach to create reliable and scalable sources of viral antigen for uses in diagnostics, therapeutics and basic biome
Externí odkaz:
https://doaj.org/article/addb994c28b44678acdeb227ced926e1
Autor:
Defeng Deng, Ratna Veeramachaneni, Andrew G Sikora, Vlad C Sandulache, William K Decker, Kazi Mokim Ahmed, Nagireddy Putluri, Vasanta Putluri, Maria F Cardenas, David A Wheeler, Andy I Frederick, Sawad Kazi, Mitchell J Frederick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background The existence of immunologically ‘cold tumors’ frequently found across a wide spectrum of tumor types represents a significant challenge for cancer immunotherapy. Cold tumors have poor baseline pan-leukocyte infiltration, including a l
Externí odkaz:
https://doaj.org/article/3658e8d79c574173b33bffd98561e7d7
Publikováno v:
Cells, Vol 11, Iss 23, p 3742 (2022)
The terminal nucleotidyltransferases TUT4 and TUT7 (TUT4/7) regulate miRNA and mRNA stability by 3′ end uridylation. In humans, TUT4/7 polyuridylates both mRNA and pre-miRNA, leading to degradation by the U-specific exonuclease DIS3L2. We investiga
Externí odkaz:
https://doaj.org/article/962780eb41e44978a316190febcd8e41
Autor:
Tarana Siddika, Nileeka Balasuriya, Mallory I. Frederick, Peter Rozik, Ilka U. Heinemann, Patrick O’Donoghue
Publikováno v:
Cells, Vol 11, Iss 23, p 3834 (2022)
Protein kinase B (AKT1) is a serine/threonine kinase and central transducer of cell survival pathways. Typical approaches to study AKT1 biology in cells rely on growth factor or insulin stimulation that activates AKT1 via phosphorylation at two key r
Externí odkaz:
https://doaj.org/article/c298f968b214421fa1429d174d9c4f93
Autor:
Wangie Yu, Yunyun Chen, Nagireddy Putluri, Abdullah Osman, Cristian Coarfa, Vasanta Putluri, Abu H. M. Kamal, Jennifer Kay Asmussen, Panagiotis Katsonis, Jeffrey N. Myers, Stephen Y. Lai, Wuhao Lu, Clifford C. Stephan, Reid T. Powell, Faye M. Johnson, Heath D. Skinner, Jawad Kazi, Kazi Mokim Ahmed, Linghao Hu, Addison Threet, Matthew D. Meyer, James A. Bankson, Tony Wang, Jack Davis, Kirby R. Parker, Madison A. Harris, Mokryun L. Baek, Gloria V. Echeverria, Xiaoli Qi, Jin Wang, Andy I. Frederick, Alex J. Walsh, Olivier Lichtarge, Mitchell J. Frederick, Vlad C. Sandulache
Publikováno v:
British Journal of Cancer. 128:2013-2024
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::154d3749722bfad6e9f8084a8ee3b730
https://doi.org/10.1038/s41416-023-02253-7
https://doi.org/10.1038/s41416-023-02253-7
Autor:
Mallory I. Frederick, Tarana Siddika, Pengcheng Zhang, Nileeka Balasuriya, Matthew A. Turk, Patrick O’Donoghue, Ilka U. Heinemann
Publikováno v:
Cells, Vol 11, Iss 5, p 821 (2022)
The phosphoinositide-3-kinase (PI3K)/AKT pathway regulates cell survival and is over-activated in most human cancers, including ovarian cancer. Following growth factor stimulation, AKT1 is activated by phosphorylation at T308 and S473. Disruption of
Externí odkaz:
https://doaj.org/article/5475aaef8228444ca137ca5e6504464e
Autor:
Wayne A. I. Frederick
Publikováno v:
Leader to Leader. 2021:18-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04752a6904b378d0649007295bbd0e23
https://doi.org/10.1002/ltl.20558
https://doi.org/10.1002/ltl.20558
Autor:
Kazi Mokim Ahmed, Ratna Veeramachaneni, Defeng Deng, Nagireddy Putluri, Vasanta Putluri, Maria F Cardenas, David A Wheeler, William K Decker, Andy I Frederick, Sawad Kazi, Andrew G Sikora, Vlad C Sandulache, Mitchell J Frederick
Publikováno v:
Journal for immunotherapy of cancer. 10(8)
BackgroundThe existence of immunologically ‘cold tumors’ frequently found across a wide spectrum of tumor types represents a significant challenge for cancer immunotherapy. Cold tumors have poor baseline pan-leukocyte infiltration, including a lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b782bbde422e74a3f1594c11929ba53
https://pubmed.ncbi.nlm.nih.gov/36002187
https://pubmed.ncbi.nlm.nih.gov/36002187
Autor:
Samuel S. Slattery, Daniel J. Giguere, Emily E. Stuckless, Arina Shrestha, Lee-Ann K. Briere, Alexa Galbraith, Stephen Reaume, Xenia Boyko, Henry H. Say, Tyler S. Browne, Mallory I. Frederick, Jeremy T. Lant, Ilka U. Heinemann, Patrick O’Donoghue, Liann Dsouza, Steven Martin, Peter Howard, Christopher Jedeszko, Kinza Ali, Garth Styba, Martin Flatley, Bogumil J. Karas, Gregory B. Gloor, David R. Edgell
Publikováno v:
Scientific reports. 12(1)
The worldwide COVID-19 pandemic caused by the SARS-CoV-2 betacoronavirus has highlighted the need for a synthetic biology approach to create reliable and scalable sources of viral antigen for uses in diagnostics, therapeutics and basic biomedical res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d174156761934a5ded90634e359680ab
https://pubmed.ncbi.nlm.nih.gov/35487958
https://pubmed.ncbi.nlm.nih.gov/35487958
Autor:
Ilka U. Heinemann, Mallory I. Frederick, Christina Z. Chung, Tarana Siddika, Nileeka Balasuriya
Publikováno v:
RNA Biol
In the cell, RNA abundance is dynamically controlled by transcription and decay rates. Posttranscriptional nucleotide addition at the RNA 3ʹ end is a means of regulating mRNA and RNA stability and activity, as well as marking RNAs for degradation. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6a1cb883b6b8b8dcab6deb774fd2b3
