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Behavioral and neuronal extracellular vesicle biomarkers associated with nicotine's enhancement of the reinforcing strength of cocaine in female and male monkeys

Autor: Mia I. Allen, Bernard N. Johnson, Ashish Kumar, Yixin Su, Sangeeta Singh, Gagan Deep, Michael A. Nader

Publikováno v: Addiction Neuroscience, Vol 11, Iss , Pp 100151- (2024)

While the majority of people with cocaine use disorders (CUD) also co-use tobacco/nicotine, most preclinical cocaine research does not include nicotine. The present study examined nicotine and cocaine co-use under several conditions of intravenous dr

Externí odkaz: https://doaj.org/article/90f8c9c4fe5e484dab73921f0bd62f70

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Using the diffusion of innovations theory to understand factors associated with COVID-19 vaccination among tobacco users.

Autor: Gail Carmen D'Souza, Jessica M Yingst, Nicolle M Krebs, Candace Bordner, Sophia I Allen, William A Calo, Andrea L Hobkirk, Jonathan Foulds

Publikováno v: PLoS ONE, Vol 19, Iss 12, p e0309780 (2024)

The coronavirus disease (COVID-19) pandemic has spread in the US with more than 100 million human infections and a million deaths since March 2020. A population of concern are high-risk individuals such as adults who are tobacco users, since COVID-19

Externí odkaz: https://doaj.org/article/5ea490e87a42436fb813294c362e9050

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Akademický článek

Defect engineering of silicon with ion pulses from laser acceleration

Publikováno v: Communications Materials, Vol 4, Iss 1, Pp 1-10 (2023)

Defect engineering and doping of semiconductors by ion irradiation are essential in large-scale integration of electronic devices. Here, intense ion pulses from a laser-accelerator, with flux levels up to 1022 ions cm-2 s-1, are used to induce and op

Externí odkaz: https://doaj.org/article/c0205fa0b2bb4659a41e7f7677695de3

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Akademický článek

Clinician perceptions of a clinical decision support system to reduce cardiovascular risk among prediabetes patients in a predominantly rural healthcare system

Autor: Daniel M. Saman, Clayton I. Allen, Laura A. Freitag, Melissa L. Harry, JoAnn M. Sperl-Hillen, Jeanette Y. Ziegenfuss, Jacob L. Haapala, A. Lauren Crain, Jay R. Desai, Kris A. Ohnsorg, Patrick J. O’Connor

Publikováno v: BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-12 (2022)

Abstract Background The early detection and management of uncontrolled cardiovascular risk factors among prediabetes patients can prevent cardiovascular disease (CVD). Prediabetes increases the risk of CVD, which is a leading cause of death in the Un

Externí odkaz: https://doaj.org/article/c5951892802b459f819fff50012ba78e

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Akademický článek

Pilot randomized controlled trial evaluating the effect of random nicotine delivery on cigarettes per day and smoke exposure

Autor: Jessica M. Yingst, Courtney Lester, Craig Livelsberger, Sophia I. Allen, Erin Hammett, Susan Veldheer, Breianna Hummer, Candace Bordner, Junjia Zhu, Christopher N. Sciamanna, Neil Trushin, Hock S. Tan, Stephen J. Wilson, Robert C. Twining, Jonathan Foulds, Patricia Sue Grigson

Publikováno v: Brain Research Bulletin, Vol 188, Iss , Pp 30-37 (2022)

Background: Many smokers report attempting to quit each year, yet most relapse, in part due to exposure to smoking-related cues. It is hypothesized that extinction of the cue-drug association could be facilitated through random nicotine delivery (RND

Externí odkaz: https://doaj.org/article/7e08790522734180b5aad2a6bd97ac17

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Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.

Autor: Meigen Yu, Hui Ye, Ruth B De-Paula, Carl Grant Mangleburg, Timothy Wu, Tom V Lee, Yarong Li, Duc Duong, Bridget Phillips, Carlos Cruchaga, Genevera I Allen, Nicholas T Seyfried, Ismael Al-Ramahi, Juan Botas, Joshua M Shulman

Publikováno v: PLoS Genetics, Vol 19, Iss 5, p e1010760 (2023)

Heterozygous variants in the glucocerebrosidase (GBA) gene are common and potent risk factors for Parkinson's disease (PD). GBA also causes the autosomal recessive lysosomal storage disorder (LSD), Gaucher disease, and emerging evidence from human ge

Externí odkaz: https://doaj.org/article/2fca0b159dad43719f3d2b2f9cfef08b

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Primary care clinicians’ opinions before and after implementation of cancer screening and prevention clinical decision support in a clinic cluster-randomized control trial: a survey research study

Autor: Melissa L. Harry, Ella A. Chrenka, Laura A. Freitag, Daniel M. Saman, Clayton I. Allen, Stephen E. Asche, Anjali R. Truitt, Heidi L. Ekstrom, Patrick J. O’Connor, Jo Ann M. Sperl-Hillen, Jeanette Y. Ziegenfuss, Thomas E. Elliott

Publikováno v: BMC Health Services Research, Vol 22, Iss 1, Pp 1-14 (2022)

Abstract Background Electronic health record (EHR)-linked clinical decision support (CDS) may impact primary care clinicians’ (PCCs’) clinical care opinions. As part of a clinic cluster-randomized control trial (RCT) testing a cancer prevention a

Externí odkaz: https://doaj.org/article/c72b8284a27547c29c9944c67079e58b

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