Zobrazeno 1 - 10
of 700
pro vyhledávání: '"I, Adler"'
Autor:
Lili Wei, Elaine Butterly, Peter Hanlon, Houra Haghpanahan, Robert Lindsay, Amanda I Adler, Luke A K Blackbourn, Sofia Dias, Katherine Hughes, Stuart McGurnaghan, John Petrie, Naveed Sattar, Laurie A Tomlinson, Nicky Welton, Sarah Wild, Jim Lewsey, David McAllister
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
Healthcare commissioners and those making reimbursement decisions require data on the “natural history” of diseases to estimate quantities such as life expectancy and quality of life. However, such data are commonly acquired from unrepresentative
Externí odkaz:
https://doaj.org/article/75af3b9526f5493d95d69f252d1c3660
Autor:
Laurence S. J. Roope, Liz Morrell, James Buchanan, Alice Ledda, Amanda I. Adler, Mark Jit, A. Sarah Walker, Koen B. Pouwels, Julie V. Robotham, Sarah Wordsworth, on behalf of the STEPUP team
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-6 (2024)
Abstract Bacteria are becoming increasingly resistant to antibiotics, reducing our ability to treat infections and threatening to undermine modern health care. Optimising antibiotic use is a key element in tackling the problem. Traditional economic e
Externí odkaz:
https://doaj.org/article/fa35e8cce60941dab2e39f24408af6bd
Autor:
Catherine J Mummery, Henrik Zetterberg, Rury R Holman, Brian Tom, Ivan Koychev, Peter Hellyer, Amanda I Adler, Elizabeth Coulthard, Benjamin R Underwood, Adam Hampshire, Charles Marshall, Paul Edison, Joanne E Milton, Joe Butchart, Francesca Cormack
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), currently marketed for type 2 diabetes and obesity, may offer novel mechanisms to delay or prevent neurotoxicity associated with Alzheimer’s disease (AD). The impact of semaglutide
Externí odkaz:
https://doaj.org/article/16420298a11d448f9195b369edad8d96
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-4 (2024)
Kabuki syndrome is a genetic disorder characterised by distinctive facial features, developmental delays, and multisystem congenital anomalies. Endocrine complications such as premature thelarche and short stature are common, whereas disorders of gly
Externí odkaz:
https://doaj.org/article/0afdb41d40a440929834de373de4259d
Autor:
M. Angelyn Bethel, Harald Sourij, Susanna R. Stevens, Karen Hannan, Yuliya Lokhnygina, Amanda I. Adler, Eric D. Peterson, Rury R. Holman, Renato D. Lopes
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-7 (2023)
Abstract Background Estimating cardiovascular (CV) event accrual is important for outcome trial planning. Limited data exist describing event accrual patterns in patients with type 2 diabetes (T2D). We compared apparent CV event accrual patterns with
Externí odkaz:
https://doaj.org/article/f5e45fcdc3fd461992ea0fb964945617
Autor:
Amanda I Adler, Nicholas R Latimer
Publikováno v:
BMJ Medicine, Vol 1, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/0d0e970085304186aa1c0b7077abd4ea
Autor:
Naveed Sattar, Sofia Dias, Sarah Wild, Laurie A Tomlinson, David McAllister, Amanda I Adler, Nicky Welton, Lili Wei, Katherine Hughes, Peter Hanlon, Elaine Butterly, Jim Lewsey, John Petrie, Robert Lindsay, Saleh A M Almazam, Khalid Alsallumi, Luke A K Blackbourn, Stuart McGurnaghan, David Phillippo
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Introduction Participants in randomised controlled trials (trials) are generally younger and healthier than many individuals encountered in clinical practice. Consequently, the applicability of trial findings is often uncertain. To address this, resu
Externí odkaz:
https://doaj.org/article/946d5f6599ce403f8514b5c0facf5297
Autor:
Haoxiang Yang, Özge Sürer, Daniel Duque, David P. Morton, Bismark Singh, Spencer J. Fox, Remy Pasco, Kelly Pierce, Paul Rathouz, Victoria Valencia, Zhanwei Du, Michael Pignone, Mark E. Escott, Stephen I. Adler, S. Claiborne Johnston, Lauren Ancel Meyers
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Selection of COVID-19 mitigation measures requires balancing health outcomes with economic impacts. Here, the authors derive a system to set triggers for increasing mitigation measures to preserve healthcare capacity, and describe how it has been use
Externí odkaz:
https://doaj.org/article/1e624f2e40294b17968d4437f8a042fa
Autor:
Kevin A. Guttenplan, Maya K. Weigel, Drew I. Adler, Julien Couthouis, Shane A. Liddelow, Aaron D. Gitler, Ben A. Barres
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Astrocyte activation may contribute to neurodegenerative disease. Here the authors show that the combined knockout of three factors known to promote astrogliosis, IL-1α, TNFα and C1qa, leads to improved survival in the SOD1 G93A mouse model of ALS.
Externí odkaz:
https://doaj.org/article/04bb3c77114848c1a13fa651c535c520
Autor:
Kamlesh Khunti, Samantha Wilkinson, Liam Smeeth, Laurie A Tomlinson, Amanda I Adler, Ian J Douglas, Andrew Briggs, Richard Grieve, Stephen O’neill, Richard J Silverwood, Paul Charlton, Patrick Bidulka, Anirban Basu
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Introduction For people with type 2 diabetes mellitus (T2DM) who require an antidiabetic drug as an add-on to metformin, there is controversy about whether newer drug classes such as dipeptidyl peptidase-4 inhibitors (DPP4i) or sodium-glucose co-tran
Externí odkaz:
https://doaj.org/article/33fdba588b1043e1a5ec01b6dca7066c