Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients

Autor: Kayani, Aasia, Geer, Amber, Ndungu, Bernard, Fawole, Bukola, Gilliam, Catherine, Adetayo, Cecelia, Barrow, Collette, Beaumont, Danielle, Prowse, Danielle, I'Anson, David, Balogun, Eni, Miah, Hakim, Shakur, Haleema, Roberts, Ian, Brooks, Imogen, Onandia, Julio, Ker, Katharine, Javaid, Kiran, Suncuan, Laura, Frimley, Lauren, Reid, Mia, Arribas, Monica, Benyahia, Myriam, Okunade, Olujide, Edwards, Phil, Chaudhri, Rizwana, Kostrov, Sergey, Kansagra, Sneha, Pepple, Tracey, Gayet-Ageron, Angèle, Prieto-Merino, David, Ageron, François-Xavier

Publikováno v: In The Lancet 13-19 January 2018 391(10116):125-132

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial

Autor: Roberts, Ian, Shakur-Still, Haleema, Afolabi, Adefemi, Akere, Adegboyega, Arribas, Monica, Brenner, Amy, Chaudhri, Rizwana, Gilmore, Ian, Halligan, Kenneth, Hussain, Irshad, Jairath, Vipul, Javaid, Kiran, Kayani, Aasia, Lisman, Ton, Mansukhani, Raoul, Mutti, Muttiullah, Arif Nadeem, Muhammad, Pollok, Richard, Simmons, Jonathan, Soomro, Majid, Stanworth, Simon, Veitch, Andrew, Hawkey, Christopher, Afolabi, Adefemi, Cuzick, Jack, Halligan, Kenneth, Henry, David, Metcalfe, Chris, Roberts, Ian, Gray, Richard, Barkun, Alan, David, Suresh, Devereaux, Philip, Brady, Tony, Roberts, Ian, Shakur-Still, Haleema, Coats, Timothy, Edwards, Phil, Gilmore, Ian, Jairath, Vipul, Ker, Katharine, Manno, Daniela, Stanworth, Simon, Veitch, Andrew, Arribas, Monica, Austin, Emma, Bal, Kiran, Balogun, Eni, Barrow, Collette, Beaumont, Danielle, Benyahia, Myriam, Brenner, Amy, Brooks, Imogen, Cargill, Madeleine, Carrington, Laura, Edwards, Phil, Frimley, Lauren, Geer, Amber, Gilbert, Daniel, Gilliam, Catherine, Gil Onandia, Julio, Golfi, Nayia, Hetherington, Daniel, Howe, Courtenay, Hughes, Carolyn, I'anson, David, Jackson, Rob, Joshi, Miland, Kansagra, Sneha, Kawahara, Taemi, Ker, Katharine, Kostrov, Sergey, Manno, Daniela, Mansukhani, Raoul, Miah, Hakim, Ndungu, Bernard, Needham, Kelly, Outtandy, Aroudra, Pearson, Daniel, Pepple, Tracey, Prowse, Danielle, Quashi, Nigel, Quinn, Anna, Ramos, Maria, Ranopa, Laura, Reid, Mia, Roberts, Ian, Roukas, Chris, Shakur-Still, Haleema, Squires, Chelci, Tanner, Jemma, Thayne, Andrew, Uddin, Ruhama, Chaudhri, Rizwana, Mutti, Muttiullah, Javaid, Kiran, Kayani, Aasia, Fawole, Bukola, Bello, Folasade Adenike, Olayemi, Oladapo, Afolabi, Adefemi, Okunade, Olujide, Adetayo, Olusade, Chaudhri, Rizwana, Mutti, Muttiullah, Afolabi, Adefemi, Bello, Folasade Adenike, Fawole, Bukola, Olayemi, Oladapo, Khamis, Hussein, Shukri Bin Jahit, Mohammad, Gogichaishvili, Tamar, Mateescu, Radu Bogdan, Adhikaree, Ajay, Abdo, Abdelmounem Eltayeib, Zaher, Mohammad, Deasy, Conor, Alvarez Gregori, Joaquin, Wellsh, Bobby, Lawton, Luke, Kamath, Raghavendra, Barry, Adrian, Carpio, Racquel, Finney, Kay, Maguire, Holly, James, Martin, Coffey, Frank, Gough, Chris, Sawers, Lisa, Thi, Aye-Aye, Simmons, Jonathan, Burnett, Claire, Jacques, Nicola, Murray, Victoria, Pollok, Richard, Jarman, Heather, Lambe, Christine, Rounding, Sarah, Tucker, Simon, Al-Idari, Romaih, Guest, Samuel, Stoddard, Emma, Yeo, David, Bergin, Colin, Hardy, Elaine, Thunder, Joanne, Jhalli, Paul, Hartley, Edward, Jarvis, Catherine, Swann, Carly, Reed, Matthew, Gallagher, Bernadette, Grahamslaw, Julia, O'Brien, Rachel, Harris, Timothy, Bellhouse, Geoffrey, Boulton, Olivia, Skene, Imogen, Stanley, Adrian, Johnstone, Janet, Maguire, Donogh, Thornton, Susan, Banks, Matthew, Bercades, Georgia, Marks, Daniel, Ryu, Jung, Harris, Timothy, Dowty, Claire, Pott, Jason, Skene, Imogen, East, James, Bailey, Adam, Beer, Sally, Davies, Sian, Appelboam, Andrew, Mackle, Daisy, Small, Jennifer, Vorwerk, Christiane, Atkins, Rachel, Bradbury, Isobel, Coats, Timothy, Bryceland, Catriona, McClelland, Lisa, Thomas, Martin, Clayton, Kate, Michael, Angiy, Haig, Stephen, Al-Nahhas, Saif, Godfrey, Tim, Boger, Philip, Comer, Rachel, Watkins, Barbara, Afolabi, Ola, Afzal, Shazad, Cowton, Amanda, Everett, Simon, Fazakerley, Ruth, Onoviran, Felicia, Snook, Jonathon, Berry, Jackie, Simpson, Diane, Keep, Jeff, Cotton, Hannah, Helyar, Sinead, Rutter, Matthew, Johnston, Tracey, O'Rourke, Laura, Chan, Louisa, Tambellini, Joanna, Trodd, Dawn, Shutt, James, Moreton, Sarah, Oglesby, Abby, Boyle, Adrian, Haeger, Nicola, Hardwick, Susie, Kendall, Jason, Faulkner, Beverley, Worner, Ruth, Hearnshaw, Sarah, Doona, Mary, Price, Maria, Hunter, Laura, Bell, Maggie, Loureiro, Vania, Kehoe, Anthony, Jefferey, Alison, Squire, Rosalyn, Hartin, David, Bell, Stephanie, Newman, Alexandra, Gagg, James, Foot, Jayne, Wakeford, Sue, May, Gabrielle, Bartram, Thomas, Cumpstay, Paul, Parker, Lucy, Das, Rita, Pahary, Sheik, Wright, Gavin, Butt, Georgina, Christmas, Natasha, Wilson, Sarah, Ashfaq, Mohammed, Chandler, Louise, Al-Nahhas, Saif, Demetriou, Carrie, Kaye, Philip, Carley, Simon, Brown, Andrew, Jones, Lucy, Whileman, Amanda, Greenaway, John, Tregonning, Julie, Harris, Timothy, Bellhouse, Geoffrey, Kuhrt, Avril, Goodacre, Steve, Jones, John, Owen, Charlotte, Mitra, Anu, Harper-Payne, Abby, Trudgill, Nigel, Hayes, Anne, Butt, Faheem, Clifford, Gayle, Kinnon, Andrew, Fowler, Susan, Pillay, Kris, Gidwani, Shweta, McNair, Alistair, Omer, Omer, de Weymarn, Tanya, Amin, Adnan, Chan, Louisa, Martin, Jane, Mathieu, Nick, Barnes, Simon, Turvill, James, Sweeting, Helen, Draegebo, Morten, McNaught, Marion, Grocutt, Mandy, Margalef, Jordi, Humphrey, Julian, Jackson, Richard, Bellis, Fionn, Hunt, Jane, Mitra, Anu, Stevenson, Alastair, Watson, Nicholas, Barden, Steven, Paterson, Stuart, Veitch, Andrew, Macdonald, Chris, Hobday, David, Orugun, Olu, Allison, Andrew, Dyer, Tristan, McBride, Samuel, Sawicki, Wojciech, Rayner, Ben, Flowerdew, Lynsey, Barbour, Jamie, Klein, Jason, Hood, Stephen, Palmer, Nicola, de Wolff, Jacob, Shenoy, Achuth, Trudgill, Nigel, Swallow, Peter, Srirajaskanthan, Rajaventhan, Hussain, Irshad, Arshad, Hamza, Aslam, Naeem, Bangash, Anam, Qamar, Muhammad, Zahoor, Haroon, Mutti, Muttiullah, Arshad, Saba, ain Ghalib, Quratul, Hameed, Tehseen, Saif, Tayyaba, Shafi, Wajahat, Arif Nadeem, Muhammad, Ali, Abid, Khan, Shehroze, Muaaz, Muhammad, Taj, Ahmad, Ghafoor, Aamir, Afridi, Aamir, Ahmad, Mansoor, Aslam, Mujahid, Kumar, Sandeep, Soomro, Majid, Ali, Mohsin, Bughio, Ubedullah, Chang, Adil, Shaikh, Sana, Ahmad, Syed, Ali, Zeeshan, Waqar, Marium, Mushir, Aiman, Sattar, Sadaf, Goraya, Saifullah, Aslam, Sharmeen, Fatima, Nighat, Noreen, Saadia, Saleem, Sheraz, Rahman, Fazal, Iqbal, Nadeem, Khalid, Mohammad, Riaz, Umar, Umar, Muhammad, Akhter, Tayyab, Khan, Javaria, Misbah, Noureen, Afzal, Muhammad, Kayani, Mobeen, Shah, Syed, Tarar, Shahida, Khan, Sherbat, Iqbal, Yasir, Khan, Essa, Reki, Maqbool, Hussain, Tanveer, Iqbal, Shafqat, Khurram, Muhammad, Shafi, Muhammad, Shaikh, Abrar, Ahmed, Aijaz, Kumar, Ameet, Sachdev, Pinkey, Nasir, Khalid Mahmood, Chaudhry, Zafar Iqbal, Zubair, Muhammad, Tayyab, Ghias, Mushtaq, Junaid, Nasir, Muhammad, Khan, Amir, Ali, Amjad, Ali, Sajjad, Uddin, Wasim, Ahmed, Sohaib, Kazmi, Tazaeen, Channa, Saleh, Aman, Adeeqa, Shaikh, Mouzam, Rizvi, Tahir, Hussain, Amjad, Baqai, Haider Zaigham, Rasheed, Zakawat, Khan, Abdus, Irfan, Adeela, Husain, Aamir, Aslam, Asifa, Yahya, Khalid, Azhar, Salman, Ul Haq, Mansoor, Afzal, Adeel, Imran, Muhammad, Saeed, Iram, Yusuf, Aasim, Hassan, Mariam, Marwat, Mumtaz, Ishfaq, Muhammad, Bashir, Tahir, Kumar, Santosh, Yaqoob, Sajjad, Wahid, Abdul, Akere, Adegboyega, Fakoya, Tinuola, Oke, Temitope, Tejan, Edries, Olaomi, Oluwole, Badejo, Olawale, Nnaemaka, Okafor, Ukwu, Nancy, Arowolo, Olukayode, Aderounmu, Adewale, Wuraola, Funmilola, Ugiagbe, Rose, Atiri, Alexander, Eghaghe, Enadeghe, Adekoya, Adeleke, Tade, Adedayo Oluyomi, Shonoiki, Olatunji, Olatoke, Samuel, Raji, Toafiq, Ekwunife, Christopher, Onyekpere, Chigozirim, Ahmed, Adamu, Muhammad, Daniyan, Odeghe, Emuobor, Lesi, Olufunmilayo, Osueni, Azeberoje, Samaila, Adamu, Nahuche, Aminu, Ajayi, Akande, Dongo, Andrew, Ijoma, Uchenna, Adebanjo, Ademola Tolulope, Igetei, Rufina, Yilkudi, Monday, Osisanya, Kehinde, Okeke, Edith Nonyelum, Enwere, Oguamanam Okezie, Esmat, Serag, Ashoush, Omar, Naga, Mazen, Nagy, Fady, Saiid, Mostafa, Shaker, Ahmed, Khamis, Hussein, Helmy, Ashraf, Saafan, Saafan, Abdel Monem, Mohammed, Din, Jiffre, Azis, Khairul, Brukan, Muhyuddin, Singh, Sanjay, Zakaria, Andee, Farid, Shaik, Hashim, Nizam, Mafauzy, Masykurin, Najmi, Wan, Amri, Nil, Yi, Xin, Hisyam, Mohammad, Ng, Elaine, Ramli, Zuhrirahimi, Yee Lim, Shyang, Voon, Kelvin, Young Yam, Sir, Jahit, Mohammad, Joon, Lee, Melikidze, Besik, Kazaishvili, Davit, Gogichaishvili, Tamar, Grubelashvili, Nino, Mosidze, Baadur, Tomadze, Gia, Megreladze, Avto, Oprita, Ruxandra, Pestroiu Calescu, Dorina, Chioncel, Camelia, Ragea, Andrei, Mateescu, Bogdan, Busuioc, Bogdan, Voiosu, Andrei, Cotirlet, Adrian, Pintilie, Iulia, Jinga, Mariana, Balaban, Daniel, Tanău, Marcel, Negreanu, Lucian, Bataga, Simona, Priya, Khushboo, Baral, Shankar, K.C., Anuj, Sah, Vijay, Yadav, Vijay, Adhikaree, Ajay, Abdo, Abdelmounem, Ahmed, Dalia, Al Anazi, Marzouqah, Al Balkhi, Areej, Deasy, Conor, Álvarez Gregori, Joaquín, Fornieles Pérez, Helio, Beqiri, Arben, Wellsh, Bobby, Lawton, Luke

Publikováno v: The Lancet; June 2020, Vol. 395 Issue: 10241 p1927-1936, 10p

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