Zobrazeno 1 - 10
of 464
pro vyhledávání: '"Hyunsu Bae"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 2871-2883 (2024)
Alzheimer’s disease (AD) is a chronic neurodegenerative disease that causes cognitive impairment. Neuroinflammation induced by activated microglia exacerbates AD. Regulatory T cells (Tregs) play roles in limiting neuroinflammation by converting mic
Externí odkaz:
https://doaj.org/article/b3b21e97e5c24090a5adfb29dfe45788
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117246- (2024)
Idiopathic pulmonary fibrosis is a progressive lung disease characterized by excessive extracellular matrix accumulation and myofibroblast proliferation with limited treatment options available. M2 macrophages are pivotal in pulmonary fibrosis, where
Externí odkaz:
https://doaj.org/article/6bd23f734b064567ac7c76915d10d49a
Autor:
Juwon Yang, Hyunsu Bae
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 9, Pp 1996-2004 (2023)
Abstract Within the tumor microenvironment (TME), regulatory T cells (Tregs) play a key role in suppressing anticancer immune responses; therefore, various strategies targeting Tregs are becoming important for tumor therapy. To prevent the side effec
Externí odkaz:
https://doaj.org/article/ba391e580c024a6785ee43f380046fe7
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 783 (2024)
The aging global population is placing an increasing burden on healthcare systems, and the social impact of Alzheimer’s disease (AD) is on the rise. However, the availability of safe and effective treatments for AD remains limited. Adoptive Treg th
Externí odkaz:
https://doaj.org/article/5330ade391c94997b35d040fe9d5f36d
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Trimethyltin (TMT) is a potent neurotoxicant that leads to hippocampal neurodegeneration. Regulatory T cells (Tregs) play an important role in maintaining the immune balance in the central nervous system (CNS), but their activitie
Externí odkaz:
https://doaj.org/article/fbcab1b541434e66800411472b89288f
Autor:
Chanmi Jeong, Jeongdong Kim, Ik-Hwan Han, Soyoung Kim, Ilseob Choi, Hongsung Kim, Jin-Hyun Jeong, Hyunsu Bae
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMelanoma has the highest mortality rate among all the types of skin cancer. In melanoma, M2-like tumor-associated macrophages (TAMs) are associated with the invasiveness of tumor cells and a poor prognosis. Hence, the depletion or reduction
Externí odkaz:
https://doaj.org/article/05ce62b8b14f435db7db02d2cefed21d
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15237 (2023)
Parkinson’s disease (PD) is a long-term neurodegenerative disease characterized by dopaminergic neuronal loss and the aggregation of alpha-synuclein (α-syn) in the brain. Cell therapy using regulatory T cells (Tregs) has therapeutic potential on P
Externí odkaz:
https://doaj.org/article/2df634a47e6b4b5cacd0908701775c21
Autor:
Chanju Lee, Hyunji Lee, Hayoon Cho, Soyoung Kim, Ilseob Choi, Young‐Sik Hwang, Hyunju Jeong, Hogi Jang, Sehyun Pak, Deok‐Sang Hwang, Ik‐Hwan Han, Hyunsu Bae
Publikováno v:
Cancer Communications, Vol 42, Iss 4, Pp 345-349 (2022)
Externí odkaz:
https://doaj.org/article/c2fba7ec1dd3451a86d020c255a10909
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Paclitaxel (sold under the brand name Taxol) is a chemotherapeutic drug that is widely used to treat cancer. However, it can also induce peripheral neuropathy, which limits its use. Although several drugs are used to attenuate neuropathy, no optimal
Externí odkaz:
https://doaj.org/article/b6245df8dea54040b8ab31397bd9d461
Autor:
Soon Uk Chae, Seong Jun Jo, Chae Bin Lee, Sangyoung Lee, Ji-Hyun Park, Jin-Su Jung, Eui-Suk Park, Hyunsu Bae, Soo Kyung Bae
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10214 (2023)
Bee venom is a traditional drug used to treat the nervous system, musculoskeletal system, and autoimmune diseases. A previous study found that bee venom and one of its components, phospholipase A2, can protect the brain by suppressing neuroinflammati
Externí odkaz:
https://doaj.org/article/549eb813b27749ce99707d62147ca6ef