Výsledky vyhledávání - "Hyunsook Ahn"

Application and Effect of the Non-face-to-face CAP+Career Group Counseling Program(CGCP) for the Career Transition of Retired Elite Female Athletes

Autor: Jaeryang Yoon, Duksun Chang, Hyunsook Ahn

Publikováno v: Korean Journal of Sport Psychology. 32:47-65

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1da37492ce4ee94082e313144dfc140
https://doi.org/10.14385/kssp.32.1.47

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Fusion of uPA to Anti-aIIbb3 Scfv Facilitates Its Uptake By in Vitro-Generated CD34+ Megakaryocytes (MKs) to Promote Targeted Fibrinolysis

Autor: Sergey Zaytsev, Hyunsook Ahn, M. Anna Kowalska, Rodney Camire, Douglas B. Cines, Mortimer Poncz, Victoria Stepanova

Publikováno v: Blood. 140:1969-1970

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c78aaa72135ceb7d71f2100f0d4e147a
https://doi.org/10.1182/blood-2022-168072

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In Situ Microscopy Studies of Infused Megakaryocytes: Implications in Thrombopoiesis

Autor: Hyunsook Ahn, Mortimer Poncz, Deborah L. French, Lubica Rauova, Ian Johnston, Danuta Jarocha, Hyunjun Kim

Publikováno v: Blood. 138:4287-4287

The questions of whether thrombopoiesis - the release of platelets from megakaryocytes - occurs both as megakaryocytes emerge from the intramedullar space or occurs as well in the pulmonary vascular bed remains unanswered. Studies by Lefrançais E, e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0eb7f07208f4a5e1879cb5b5b2bd468a
https://doi.org/10.1182/blood-2021-150764

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Insights into Endogenous Vs Exogenous Cargo-Containing Platelet Alpha-Granules

Autor: Hyunsook Ahn, Sergey Zaytsev, Victoria Stepanova, Douglas B. Cines, Deborah L. French, Mortimer Poncz, M. Anna Kowalska, Khalil Bdeir, Rodney M. Camire

Publikováno v: Blood. 138:1028-1028

Alpha granules in megakaryocytes contain a mixture of endogenously expressed proteins as well as proteins taken up from the intramedullar fluid. Both pools are thought to be found in all alpha granules in the megakaryocytes and released platelets. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76e48b3e602a78db2391bbff88196e86
https://doi.org/10.1182/blood-2021-153348

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A Novel Platelet-Targeting Fibrinolytic Strategy: Endocytosed Urokinase By Megakaryocytes Is Stored in α-Granules and Is Functional In Vivo in a Murine Model of Thrombosis

Autor: Victoria Stepanova, Mortimer Poncz, Khalil Bdeir, Sergei Zaitsev, Hyunsook Ahn, Douglas B. Cines, John Tkaczynski

Publikováno v: Blood. 134:3627-3627

We have been interested in developing fibrinolytic agents that have a prolonged half-life and can selectively prevent new thrombi from forming without destabilizing established hemostatic clots. We believe that platelet-targeting of urokinase plasmin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba119c3984969df3ab05af664e437a59
https://doi.org/10.1182/blood-2019-124501

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A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis

Autor: Deborah L. French, Rodney M. Camire, Denise E. Sabatino, Sara Borst, Francis Ayombil, Hyunsook Ahn, Mortimer Poncz, Paul Gadue, John Tkaczynski, Randolph B. Lyde

Publikováno v: Blood. 134:1102-1102

Human platelets endocytose coagulation factor (F) V into their α-granules, in part, via low-density lipoprotein (LDL) receptor-related protein 1 (LRP1). In contrast to humans, mouse FV is endogenously expressed during megakaryopoiesis and stored in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5c4940ddc34337e170d037505cc6cde
https://doi.org/10.1182/blood-2019-124788

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A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice

Autor: Hyunsook Ahn, Randolph B. Lyde, Mortimer Poncz, Zaverio M. Ruggeri, Shu-Wha Lin, Sergei Zaistev, Vincent Hayes, Renhao Li, Douglas B. Cines, Vladimir R. Muzykantov

Publikováno v: Blood. 132:990-990

We previously described (Fuentes, J Clin Invest 2016) a chimeric protein, GPIIb/uPA-T, that provided effective thromboprophylaxis composed of an N-terminal scFv specifically to human (h) GPIIb linked to a C-terminal variant of low molecular weight ur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9389a3fa19bd9d0c497f7fb603d1b6fa
https://doi.org/10.1182/blood-2018-99-115262

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