Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Hyunsook, Lee"'
Publikováno v:
mSystems, Vol 9, Iss 3 (2024)
ABSTRACTSince the 1980s, the development of new drug classes for the treatment of multidrug-resistant Klebsiella pneumoniae has become limited, highlighting the urgent need for novel antibiotics. To address this challenge, this study aimed to explore
Externí odkaz:
https://doaj.org/article/7ddd34215c574ada97c7f3fdee120f62
Autor:
Youngil Koh, Hyemin Kim, So Young Joo, Seulki Song, Young Hoon Choi, Hyung Rae Kim, Byul Moon, Jamin Byun, Junshik Hong, Dong-Yeop Shin, Solip Park, Kwang Hyuck Lee, Kyu Taek Lee, Jong Kyun Lee, Daechan Park, Se-Hoon Lee, Jin-Young Jang, Hyunsook Lee, Jung-Ae Kim, Sung-Soo Yoon, Joo Kyung Park
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Lysosomes are closely linked to autophagic activity, which plays a vital role in pancreatic ductal adenocarcinoma (PDAC) biology. The survival of PDAC patients is still poor, and the identification of novel genetic factors for pro
Externí odkaz:
https://doaj.org/article/009bbecbecae404a8ed7c2e23cb50d90
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
G-quadruplex (G4) can be formed in telomeric DNA. Here the authors show that BRCA2 interacts with telomere G4 structure generated during telomere replication, protecting telomere from nuclease attack.
Externí odkaz:
https://doaj.org/article/24a7e5fb6b1b441f8bac246643284d55
Publikováno v:
AIP Advances, Vol 13, Iss 2, Pp 025344-025344-4 (2023)
Maintenance of homoeostasis in human body is a very important indicator in all cell activities. When exposed to a disease, various immune cells are activated due to the inflammatory response, and particularly T cells play a role in inducing apoptosis
Externí odkaz:
https://doaj.org/article/d3170f027376411188af3ed9ca2c404e
Autor:
Roshan D’Souza, Le Phuong Nguyen, Naina A. Pinto, Hyunsook Lee, Thao Nguyen Vu, Hoyoung Kim, Hyun Soo Cho, Dongeun Yong
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background A complex cascade of genes, enzymes, and transcription factors regulates AmpC β-lactamase overexpression. We investigated the network of AmpC β-lactamase overexpression in Klebsiella aerogenes and identified the role of AmpG in
Externí odkaz:
https://doaj.org/article/4376f67f12a24be7b8757b308ae34f75
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The identification of single point mutations is an important step toward personalizing detection and treatment. Here the authors design a gold-bridged nanoparticle for sensing MutS affinities to point mutations, and compile an atlas of the affinity d
Externí odkaz:
https://doaj.org/article/eb28fcf5d4c94403984e0e12ea52b0be
Autor:
Seunghwan Bang, Hyunsook Lee
Publikováno v:
AIP Advances, Vol 11, Iss 1, Pp 015242-015242-4 (2021)
The blood’s acid-base balance is precisely controlled because even a minor deviation from the normal range can severely affect many organs. Due to the Warburg effect, in tumor cells, an imbalance between oxygen supply and consumption and the accumu
Externí odkaz:
https://doaj.org/article/50f13994416249398c2b17c64e7596c1
Publikováno v:
Life, Vol 12, Iss 4, p 469 (2022)
Many studies have demonstrated a reduced number and vasculogenic capacity of endothelial colony-forming cells (ECFCs) in diabetic patients. However, whether the vasculogenic capacity of ECFCs is recovered or not when combined with pericyte precursors
Externí odkaz:
https://doaj.org/article/e0b1fad7fdd34edbb61d5576776a3729
Autor:
Youngae Kim, Hyunsook Lee
Publikováno v:
Asia-pacific Journal of Convergent Research Interchange. 9:317-328
Publikováno v:
AIP Advances, Vol 10, Iss 1, Pp 015005-015005-4 (2020)
It is widely known that abnormal peripheral blood circulation due to intravascular stenosis causes ischemic diseases and blood circulatory disorders. The purpose of this study was to investigate the influence of pulsed magnetic field (PMF) on hemodyn
Externí odkaz:
https://doaj.org/article/4662671685b54187a43b9e5165ce7eac