Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Hyunkoo Kang"'
Publikováno v:
eLife, Vol 12 (2023)
Cranial irradiation is used for prophylactic brain radiotherapy as well as the treatment of primary brain tumors. Despite its high efficiency, it often induces unexpected side effects, including cognitive dysfunction. Herein, we observed that mice ex
Externí odkaz:
https://doaj.org/article/1c71d66d87ed458d83eab07b73a3b97d
Autor:
Hyunkoo Kang, Sungmin Lee, Kyeongmin Kim, Jaewan Jeon, Seok-Gu Kang, HyeSook Youn, Hae Yu Kim, BuHyun Youn
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Glioblastoma Multiforme (GBM) is a malignant primary brain tumor in which the standard treatment, ionizing radiation (IR), achieves a median survival of about 15 months. GBM harbors glioblastoma stem-like cells (GSCs), which play
Externí odkaz:
https://doaj.org/article/6af6b12566b44d879b505d1465581b4d
Publikováno v:
Neurobiology of Stress, Vol 16, Iss , Pp 100423- (2022)
Selective serotonin reuptake inhibitors (SSRIs) are effective first line therapies for treating depression, but are plagued by undesirable side effects and are not effective in all patients. Because SSRIs effectively deplete the neuronal releasable s
Externí odkaz:
https://doaj.org/article/f848bd3098cd4481a30368c37dc9dc8b
Exosomal Plasminogen Activator Inhibitor-1 Induces Ionizing Radiation-Adaptive Glioblastoma Cachexia
Autor:
Eunguk Shin, Hyunkoo Kang, Haksoo Lee, Sungmin Lee, Jaewan Jeon, Kimoon Seong, Hyesook Youn, Buhyun Youn
Publikováno v:
Cells, Vol 11, Iss 19, p 3102 (2022)
Cancer cachexia is a muscle-wasting syndrome that leads to a severely compromised quality of life and increased mortality. A strong association between cachexia and poor prognosis has been demonstrated in intractable cancers, including glioblastoma (
Externí odkaz:
https://doaj.org/article/50c995b7a5cd43d997a68c4941fd332f
Autor:
Hyunkoo Kang, Haksoo Lee, Dahye Kim, Byeongsoo Kim, JiHoon Kang, Hae Yu Kim, HyeSook Youn, BuHyun Youn
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1308 (2022)
Glioblastoma (GBM) is the most malignant primary brain tumor. The current standard approach in GBM is surgery, followed by treatment with radiation and temozolomide (TMZ); however, GBM is highly resistant to current therapies, and the standard of car
Externí odkaz:
https://doaj.org/article/a8834139f2bd40768105c03f4ca554e8
Autor:
Eunguk Shin, Sungmin Lee, Hyunkoo Kang, Jeongha Kim, Kyeongmin Kim, HyeSook Youn, Young Woo Jin, Songwon Seo, BuHyun Youn
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Ionizing radiation (IR) is a high-energy radiation whose biological effects depend on the irradiation doses. Low-dose radiation (LDR) is delivered during medical diagnoses or by an exposure to radioactive elements and has been linked to the occurrenc
Externí odkaz:
https://doaj.org/article/b701722afbbc43dba102cd56d861f2a1
Autor:
Sungmin Lee, Beomseok Son, Jaewan Jeon, Gaeul Park, Hyunwoo Kim, Hyunkoo Kang, HyeSook Youn, Sunmi Jo, Jie-Young Song, BuHyun Youn
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 6, Pp 2233-2249 (2018)
Background/Aims: Non-alcoholic fatty liver disease (NAFLD) is an emerging metabolic disease. Although it leads to severe hepatic diseases including steatohepatitis, cirrhosis, and hepatic cancer, little is known about therapy to prevent and cure hepa
Externí odkaz:
https://doaj.org/article/8e1f58381cb64c2d8ea3f61d666046e6
Autor:
Hyunkoo Kang
Publikováno v:
Stroke. 54
Introduction: We investigated the relationship between the level of cerebral collateral circulation on arterial spin-labeling (ASL) magnetic resonance imaging (MRI) and cerebrovascular reserve (CVR) on acetazolamide (ACZ)-stress single photon emissio
Publikováno v:
New Physics: Sae Mulli. 71:1004-1009
Publikováno v:
Nutrients, Vol 14, Iss 95, p 95 (2022)
Nutrients
Nutrients; Volume 14; Issue 1; Pages: 95
Nutrients
Nutrients; Volume 14; Issue 1; Pages: 95
Increased triglyceride, cholesterol, and low-density lipoprotein (LDL) levels cause hyperlipidemia. Despite the availability of statin-based drugs to reduce LDL levels, additional effective treatments for reducing blood lipid concentrations are requi