Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Hyungshin Yim"'
Autor:
Hyun-Ji Oh, Abdulhamid B. Imam-Aliagan, Yeo-Bin Kim, Hyun-Jin Kim, Issac A. Izaguirre, Chang K. Sung, Hyungshin Yim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Despite recent advances in cancer diagnostics and treatment, the mortality associated with lung cancer is still the highest in the world. Late-stage diagnosis, often accompanied by metastasis, is a major contributor to the high mortality rates, empha
Externí odkaz:
https://doaj.org/article/0477eebc3d41476abc4e768a5b4248da
Autor:
Rong Xu, Young-Joo Lee, Chang-Hyeon Kim, Ga-Hong Min, Yeo-Bin Kim, Jung-Won Park, Dae-Hoon Kim, Jung-Hyun Kim, Hyungshin Yim
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-25 (2023)
Abstract Background Understanding the mechanism behind immune cell plasticity in cancer metastasis is crucial for identifying key regulators. Previously we found that mitotic factors regulate epithelial-mesenchymal transition, but how these factors c
Externí odkaz:
https://doaj.org/article/5160280061be4f78afecbecb53ccef5e
Autor:
Elisabet Ampudia-Mesias, Charles S. Cameron, Eunjae Yoo, Marcus Kelly, Sarah M. Anderson, Riley Manning, Juan E. Abrahante Lloréns, Christopher L. Moertel, Hyungshin Yim, David J. Odde, Nurten Saydam, Okay Saydam
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4416 (2024)
Medulloblastoma (MB) encompasses diverse subgroups, and leptomeningeal disease/metastasis (LMD) plays a substantial role in associated fatalities. Despite extensive exploration of canonical genes in MB, the molecular mechanisms underlying LMD and the
Externí odkaz:
https://doaj.org/article/904ab838c5e0474c8f15d4089df2085b
Autor:
Seong Hee Kang, Hyung Joon Yim, Ji-won Hwang, Mi-jung Kim, Young-Sun Lee, Young Kul Jung, Hyungshin Yim, Baek-Hui Kim, Hae-Chul Park, Yeon Seok Seo, Ji Hoon Kim, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun
Publikováno v:
The Korean Journal of Internal Medicine, Vol 37, Iss 4, Pp 745-756 (2022)
Background/Aims Efficient anti-fibrotic therapies are required for the treatment of liver cirrhosis. Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) and cyclooxygenase-2 (COX-2) inhibitors have been reported to have anti-fibrotic effe
Externí odkaz:
https://doaj.org/article/a4ee430522484af189b383a33b57a75c
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Backgrounds: Despite the clinical success of taxanes, they still have limitations, such as chemoresistance. To overcome the limitations of paclitaxel, genetic alterations and targeting effects of altered genes were observed in paclitaxel-resistant ca
Externí odkaz:
https://doaj.org/article/bfc40918d0e34245a3d2d2b5aede5ee0
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8629 (2020)
USP7 is a promising target for the development of cancer treatments because of its high expression and the critical functions of its substrates in carcinogenesis of several different carcinomas. Here, we demonstrated the effectiveness of targeting US
Externí odkaz:
https://doaj.org/article/b7b2b673fe32479baa6f8264e11c6398
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2420 (2019)
Increased health awareness among the public has highlighted the health benefits of dietary supplements including flavonoids. As flavonoids target several critical factors to exert a variety of biological effects, studies to identify their target-spec
Externí odkaz:
https://doaj.org/article/39624858344d4238b393ea20fba669d5
Autor:
Chang Kyoo Sung, Hyungshin Yim, Hongcang Gu, Dawei Li, Erik Andrews, Sekhar Duraisamy, Cheng Li, Ronny Drapkin, Thomas Benjamin
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46486 (2012)
p150, product of the SALL2 gene, is a binding partner of the polyoma virus large T antigen and a putative tumor suppressor. p150 binds to the nuclease hypersensitive element of the c-MYC promoter and represses c-MYC transcription. Overexpression of p
Externí odkaz:
https://doaj.org/article/f94d553d159b4acf8dce1dd974bde48a
Publikováno v:
Theranostics. 13:1198-1216
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::197a0215843f9920b59687f4923c71ee
https://doi.org/10.7150/thno.79318
https://doi.org/10.7150/thno.79318
Publikováno v:
Cell Biology and Toxicology.
The Plk2 is a cellular stress-responsive factor that is induced in response to oxidative stress. However, the roles of Plk2 in acute kidney injury (AKI) have not been clarified. We previously found that Plk2 is an interacting factor of Nrf2 in respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35d1ac32e22a2e5e2fcec9023f1a5680
https://doi.org/10.1007/s10565-022-09741-1
https://doi.org/10.1007/s10565-022-09741-1